Natural biomarocmolecule-based antimicrobial hydrogel for rapid wound healing: A review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 244, P. 125454 - 125454

Published: June 16, 2023

Language: Английский

---

Hydrogel-based dressings designed to facilitate wound healing

Materials Advances, Journal Year: 2023, Volume and Issue: 5(4), P. 1364 - 1394

Published: Dec. 20, 2023

This review provides an overview of the functionalities hydrogel-based dressings and their role in promoting wound healing.

Language: Английский

---

Stimuli‐Responsive Hydrogels for Antibacterial Applications

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(22)

Published: May 9, 2024

Hydrogels have emerged as promising candidates for biomedical applications, especially in the field of antibacterial therapeutics, due to their unique structural properties, highly tunable physicochemical and excellent biocompatibility. The integration stimuli-responsive functions into hydrogels holds potential enhance properties therapeutic efficacy, dynamically responding different external or internal stimuli, such pH, temperature, enzymes, light. Therefore, this review describes applications hydrogel dressings responsive stimuli therapy. collaborative interaction between materials is discussed. This synergistic approach, contrast conventional materials, not only amplifies effect but also alleviates adverse side effects diminishes incidence multiple infections drug resistance. provides a comprehensive overview current challenges outlines future research directions hydrogels. It underscores imperative ongoing interdisciplinary aimed at unraveling mechanisms wound healing. understanding crucial optimizing design implementation Ultimately, aims offer scientific guidance development practical clinical application dressings.

Language: Английский

---

Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(30)

Published: July 22, 2024

Abstract Due to repeated microbial infection, persistent inflammation, excessive oxidative stress, and cell dysfunction, chronic wounds are difficult heal, posing a serious threat public health. Therefore, developing multifunctional wound dressings that can regulate the complex microenvironment of enhance cellular function holds great significance. Recently, chitosan has emerged as promising biopolymer for healing due its excellent biocompatibility, biodegradability, versatile bioactivity. The aim this review is provide comprehensive understanding mechanisms delayed discuss healing–promoting properties derivatives, such good antibacterial activity, hemostatic capacity, ability promote tissue regeneration. On basis, potential applications chitosan‐based hydrogels summarized in healing, including providing suitable microenvironment, eliminating bacterial infections, promoting hemostasis, inhibiting alleviating In addition, concerns perspectives clinical application also discussed.

Language: Английский

---

Multi-Functional hydrogels to promote diabetic wound Healing: A review

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 497, P. 154855 - 154855

Published: Aug. 14, 2024

Language: Английский

---

Recent advances of hydrogels as smart dressings for diabetic wounds

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(5), P. 1126 - 1148

Published: Jan. 1, 2024

This review highlights the latest progress of smart hydrogel dressings for bandaging, monitoring and therapy diabetic wounds.

Language: Английский

---

Cellulose-reinforced poly(Ionic Liquids) composite hydrogel for infected wounds therapy and real-time reliable bioelectronic

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 476, P. 146816 - 146816

Published: Oct. 21, 2023

Language: Английский

---

pH factors in chronic wound and pH-responsive polysaccharide-based hydrogel dressings

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135118 - 135118

Published: Aug. 28, 2024

Language: Английский

---

Smart sensors and wound dressings: Artificial intelligence-supported chronic skin monitoring – A review

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 497, P. 154371 - 154371

Published: July 29, 2024

Language: Английский

---

Glucose Oxidase Energized Osmium with Dual‐Active Centers and Triple Enzyme Activities for Infected Diabetic Wound Management

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(16)

Published: March 20, 2024

Diabetic wounds are susceptible to bacterial infections, largely linked high blood glucose levels (hyperglycemia). To treat such wounds, enzymes like oxidase (GOx) can be combined with nanozymes (nanomaterials mimic enzymes) use effectively for purposes. However, there is still room improvement in these systems, particularly terms of process simplification, enzyme activity regulation, and treatment effects. Herein, the approach utilizes GOx directly facilitate biomineralized growth osmium (Os) nanozyme (GOx-OsNCs), leading dual-active centers remarkable triple activities. Initially, GOx-OsNCs vicinal centers, enabling a self-cascaded mechanism that significantly enhances sensing performance compared step-by-step reactions, surpassing capabilities other metal sources as gold platinum. In addition, integrated into glucose-sensing gel, instantaneous visual feedback. infected diabetic exhibit multifaceted benefits by lowering exhibiting antibacterial properties through generation hydroxyl free radicals, thereby expediting healing fostering favorable microenvironment. Furthermore, catalase-like aids reducing oxidative stress, inflammation, hypoxia, culminating improved outcomes. Overall, this synergistic enzyme-nanozyme blend user-friendly holds considerable promise diverse applications.

Language: Английский

---