Responsive hydrogel modulator with self-regulated polyphenol release for accelerating diabetic wound healing via precise immunoregulation
Yunfei Tan,
No information about this author
Лей Ма,
No information about this author
Yixuan Wu
No information about this author
et al.
Journal of Materials Chemistry B,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Responsive
hydrogels
were
capable
of
achieving
the
spatiotemporally
controlled
release
polyphenol
that
relieved
severe
oxidative
stress
and
modulated
macrophage
polarization,
thus
accelerating
diabetic
wound
healing.
Language: Английский
Photothermal effect-enhanced antibacterial hydrogel with anti-inflammation and anti-oxidation properties: Macrophage polarization promotes infected wound healing
Yixuan Wu,
No information about this author
Лей Ма,
No information about this author
Yunfei Tan
No information about this author
et al.
Chemical Engineering Journal,
Journal Year:
2025,
Volume and Issue:
unknown, P. 161400 - 161400
Published: March 1, 2025
Language: Английский
Recent advances in tea and other plant polyphenol biomaterials for antibacterial and disease treatment
Beverage Plant Research,
Journal Year:
2025,
Volume and Issue:
5(1), P. 0 - 0
Published: Jan. 1, 2025
Language: Английский
A Multitarget Synergistic Core‐Shell Nanogel for Experimental Periodontitis Treatment
Qingchen Cui,
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Linrong Yu,
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Xixi Song
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et al.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 5, 2025
Abstract
Periodontitis,
a
multifactorial
inflammatory
disease
affecting
periodontal
tissues,
threatens
the
oral
health
of
millions
worldwide.
Traditional
single‐target
treatments
are
insufficient
for
addressing
disease's
complex
pathological
mechanisms.
This
study
presents
novel
multitarget
synergistic
core‐shell
nanogel,
type
biocompatible
nanosized
polymeric
material
with
hydrogel‐like
properties
designed
periodontitis
treatment.
The
nanogel
comprises
quaternized
chitosan‐polydopamine
(CSQ–PDA)
shell
and
resveratrol
(RES)‐loaded
casein
nanomicelles
(R@C)
core.
Nanomicelles
can
self‐assemble
in
water
to
enhance
solubility
RES,
thus
improving
its
functional
vivo.
CSQ–PDA
be
self‐polymerized
noncovalently
bound
R@C
form
(R@C)PC
without
any
organic
reagents.
design
allows
remodel
immune
microenvironment
by
promoting
macrophage
M2
polarization,
downregulating
proinflammatory
factors,
upregulating
anti‐inflammatory
factors.
Its
significant
antioxidant
capacity
also
upregulate
superoxide
dismutase
scavenge
reactive
oxygen
species.
Notably,
this
cationic
target
bind
bacteria
electrostatic
interaction
has
an
effective
photothermal
conversion
ability
antimicrobial
therapy.
high
adhesion
minimal
fluidity
ensure
precise,
sustained
treatment
periodontitis.
results
demonstrate
that
is
promising
nanoplatform
enhancing
efficacy.
Language: Английский
Capillary‐Driven 3D Open Fluidic Networks for Versatile Continuous Flow Manipulation
Shuangmei Wu,
No information about this author
Siqi Sun,
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Ye Jia
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et al.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 5, 2025
Abstract
Human
civilization
hinges
on
the
capability
to
manipulate
continuous
flows.
However,
flows
are
often
regulated
in
closed‐pipe
configurations
address
their
instability,
isolating
from
environment
and
considerably
restricting
functionality.
Manipulating
open
systems
remains
challenging.
Here,
capillary‐driven
3D
fluidic
networks
(OFNs)
composed
of
connected
polyhedral
frames
reported.
Each
frame
acts
as
a
fluid
chamber
with
free
interfaces
that
enable
entry
exit;
connecting
rods
function
valves,
allowing
precise
control
over
direction,
velocity,
path
flow.
The
OFNs
seamlessly
adapt
various
systems,
enabling
manipulation
multiple
Leveraging
these
distinctive
features,
series
applications,
including
selective
metallization,
programmable
mixing
diagnostics,
spatiotemporal
multi‐step
reactions,
achieved.
OFNs’
also
facilitate
controlled
drug
release
efficient
heat
exchange.
These
versatile
will
significantly
advance
technological
innovations
engineering,
microfluidics,
interfacial
chemistry,
biomedicine.
Language: Английский