Advances in Direct Fluoroalkylation of Organic Substrates with Partially Fluorinated Alkyl Motivs DOI
Sebastián Barata‐Vallejo, Sergio M. Bonesi, Al Postigo

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(21), P. 15879 - 15907

Published: Oct. 11, 2024

Partially fluorinated alkyl groups other than methyl are increasingly playing crucial roles in the development of drugs with diverse biological activities, thus creating an innovative chemical space within organofluorine chemistry. For studies structure–activity relationships, late-stage modification such or substituents into substrates that bear activity is essential. This perspective will study catalytic protocols for direct introduction partially monofluoroalkylated (−CHFR, –CH2CH2F), difluoroalkylated (−CF2Me, –CH2CF2H), trifluoroalkylated (−CHR(CF3), –CH2CF3, –CH2CH2CF3, –CH(Me)CF3, –C(Me)2CF3), and pentafluoropropylated (−CH2C2F5) onto (hetero)aromatic compounds, double bonds, isonitriles, halides, N, O, S atoms.

Language: Английский

Revealing the Phonon Bottleneck Limit in Negatively Charged CdS Quantum Dots DOI
Skylar J. Sherman, Bokang Hou, Matthew J. O’Rourke

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

The capture of photoexcited hot electrons in semiconductors before they lose their excess energy to cooling is a long-standing goal photon conversion. Semiconductor nanocrystals have large electron spacings that are expected slow down relaxation by phonon emission, but nanocrystals, nevertheless, cool rapidly transfer holes. This makes the intrinsic phonon-bottleneck-limited lifetime elusive. We used combination theory and experiments probe hot-electron dynamics negatively charged cadmium sulfide (CdS) colloidal quantum dots (QDs) absence Experiments found these cooled on 100 ps time scale. Theoretical simulations predicted pure occurs similar similarity suggests experimental measurements reflect upper limit lifetimes CdS QDs lower rates processes can harvest those electrons.

Language: Английский

Citations

0
PFAS removal via adsorption: A synergistic review on advances of experimental and computational approaches DOI
Hansini Abeysinghe, Xingmao Ma, Mesfin Tsige

et al.

Chemosphere, Journal Year: 2025, Volume and Issue: 377, P. 144323 - 144323

Published: March 29, 2025

Language: Английский

Citations

0
La Doping ATaO3 (A = Li, Na, K) to Improve Performance for Photocatalytic Pollutant Degradation DOI
Rachael Matthews, Huong Lan Thi Nguyen, Faqing Yang

et al.

Chemistry of Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 6, 2025

Language: Английский

Citations

0
Advances in Direct Fluoroalkylation of Organic Substrates with Partially Fluorinated Alkyl Motivs DOI
Sebastián Barata‐Vallejo, Sergio M. Bonesi, Al Postigo

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(21), P. 15879 - 15907

Published: Oct. 11, 2024

Partially fluorinated alkyl groups other than methyl are increasingly playing crucial roles in the development of drugs with diverse biological activities, thus creating an innovative chemical space within organofluorine chemistry. For studies structure–activity relationships, late-stage modification such or substituents into substrates that bear activity is essential. This perspective will study catalytic protocols for direct introduction partially monofluoroalkylated (−CHFR, –CH2CH2F), difluoroalkylated (−CF2Me, –CH2CF2H), trifluoroalkylated (−CHR(CF3), –CH2CF3, –CH2CH2CF3, –CH(Me)CF3, –C(Me)2CF3), and pentafluoropropylated (−CH2C2F5) onto (hetero)aromatic compounds, double bonds, isonitriles, halides, N, O, S atoms.

Language: Английский

Citations

2