Chemical Society Reviews,
Journal Year:
2010,
Volume and Issue:
40(1), P. 387 - 426
Published: Aug. 17, 2010
The
study
of
biological
systems
in
a
holistic
manner
(systems
biology)
is
increasingly
being
viewed
as
necessity
to
provide
qualitative
and
quantitative
descriptions
the
emergent
properties
complete
system.
Systems
biology
performs
studies
focussed
on
complex
interactions
system
components;
emphasising
whole
rather
than
individual
parts.
Many
perturbations
mammalian
(diet,
disease,
drugs)
are
multi-factorial
small
parts
insufficient
understand
phenotypic
changes
induced.
Metabolomics
one
functional
level
tool
employed
investigate
metabolites
with
other
(metabolism)
but
also
regulatory
role
through
interaction
genes,
transcripts
proteins
(e.g.
allosteric
regulation).
Technological
developments
driving
force
behind
advances
scientific
knowledge.
Recent
two
analytical
platforms
mass
spectrometry
(MS)
nuclear
magnetic
resonance
(NMR)
spectroscopy
have
driven
forward
discipline
metabolomics.
In
this
critical
review,
an
introduction
metabolites,
metabolomes,
metabolomics
MS
NMR
will
be
provided.
applications
for
health-disease
continuum,
drug
efficacy
toxicity
dietary
effects
health
reviewed.
current
limitations
future
goals
discussed
(374
references).
International Journal of Epidemiology,
Journal Year:
2012,
Volume and Issue:
41(4), P. 1187 - 1203
Published: Aug. 1, 2012
Introduction
The
use
of
innovative
technologies
is
deemed
to
improve
dietary
assessment
in
various
research
settings.
However,
their
relative
merits
nutritional
epidemiological
studies,
which
require
accurate
quantitative
estimates
the
usual
intake
at
individual
level,
still
need
be
evaluated.
Objective
To
report
on
inventory
available
for
and
critically
evaluate
strengths
weaknesses
as
compared
with
conventional
methodologies
(i.e.
Food
Frequency
Questionnaires,
food
records,
24-hour
recalls)
used
studies.
Methods
A
list
currently
was
identified
from
English-language
journals,
using
PubMed
Web
Science.
search
criteria
were
principally
based
date
publication
(between
1995
2011)
pre-defined
keywords.
Results
Six
main
groups
('Personal
Digital
Assistant-',
'Mobile-phone-',
'Interactive
computer-',
'Web-',
'Camera-
tape-recorder-'
'Scan-
sensor–based'
technologies).
Compared
Personal
Assistant
mobile
phone
devices
seem
recording
through
possibility
'real-time'
eating
events,
but
validity
estimate
intakes
low
moderate.
In
recalls,
there
limited
knowledge
regarding
accuracy
fully
automated
approaches;
methodological
problems,
such
inaccuracy
self-reported
portion
sizes
might
more
critical
than
interview-based
applications.
contrast,
measurement
errors
web-based
paper-based
Questionnaires
are
most
likely
similar,
suggesting
that
underlying
methodology
unchanged
by
technology.
Conclusions
Most
new
seen
have
overlapping
features
methods
predominantly
epidemiology.
Their
potential
enhance
cost-
time-effective,
less
laborious
ways
data
collection
higher
subject
acceptance,
though
integration
studies
would
additional
considerations,
study
objectives,
target
population
financial
resources
available.
even
technologies,
inherent
bias
related
will
not
resolved.
More
therefore
crucial
investigate
technologies.
F1000Research,
Journal Year:
2017,
Volume and Issue:
6, P. 926 - 926
Published: June 16, 2017
Self-reported
dietary
intake
is
assessed
by
methods
of
real-time
recording
(food
diaries
and
the
duplicate
portion
method)
recall
(dietary
histories,
food
frequency
questionnaires,
24-hour
recalls).
Being
less
labor
intensive,
are
more
frequently
employed
in
nutritional
epidemiological
investigations.
However,
sources
error,
which
include
participants’
inability
to
fully
accurately
their
intakes
as
well
limitations
inherent
composition
databases
applied
convert
reported
consumption
energy
nutrient
intakes,
may
limit
validity
generated
information.
The
use
biomarkers
often
recommended
overcome
such
errors
better
capture
intra-individual
variability
intake;
nevertheless,
it
has
its
own
challenges.
To
address
measurement
error
associated
with
large
investigations
integrate
sub-studies
for
validation
calibration
questionnaires
and/or
administer
a
combination
different
assessment
(e.g.
administration
biomarker
levels).
Recent
advances
omics
field
could
enrich
list
reliable
nutrition
biomarkers,
whereas
new
approaches
employing
web-based
smart
phone
applications
reduce
respondent
burden
and,
possibly,
reporting
bias.
Novel
technologies
increasingly
integrated
traditional
methods,
but
some
still
remain.
In
analyses,
always
need
be
adjusted
total
daily
account
related
reporting.
American Journal of Clinical Nutrition,
Journal Year:
2018,
Volume and Issue:
108(5), P. 1069 - 1091
Published: April 27, 2018
High
dietary
intake
or
blood
concentrations
(as
biomarkers
of
intake)
vitamin
C,
carotenoids,
and
E
have
been
associated
with
reduced
risk
cardiovascular
disease,
cancer,
mortality,
but
these
associations
not
systematically
assessed.
Nutrition Journal,
Journal Year:
2012,
Volume and Issue:
11(1)
Published: Dec. 1, 2012
The
subjective
nature
of
self-reported
dietary
intake
assessment
methods
presents
numerous
challenges
to
obtaining
accurate
and
nutritional
status.
This
limitation
can
be
overcome
by
the
use
biomarkers,
which
are
able
objectively
assess
consumption
(or
exposure)
without
bias
errors.
need
for
biomarkers
was
addressed
Institute
Medicine,
who
recognized
lack
as
a
knowledge
gap
requiring
future
research.
purpose
this
article
is
review
existing
literature
on
currently
available
including
novel
specific
foods
components,
validity,
reliability
sensitivity
markers.
revealed
several
in
additional
validation
research;
research
also
needed
produce
sensitive,
specific,
cost-effective
noninvasive
biomarkers.
emerging
field
metabolomics
may
help
advance
development
food/nutrient
yet
advances
food
metabolome
databases
needed.
availability
that
estimate
components
could
greatly
enhance
targeting
compliance
national
recommendations
well
direct
associations
with
disease
outcomes.
More
necessary
refine
accounting
confounding
factors,
establish
new
indicators
intake,
develop
techniques
cost-effective,
noninvasive,
rapid
measures
