Brief Cognitive Behavioral Therapy for Suicidal Inpatients

JAMA Psychiatry, Journal Year: 2024, Volume and Issue: 81(12), P. 1177 - 1177

Published: Sept. 11, 2024

Importance Suicide risk is elevated after discharge from inpatient level of care. Empirically supported suicide prevention treatments are needed. Objective To determine whether adding an version brief cognitive behavioral therapy for to treatment as usual reduces postdischarge attempts, suicidal ideation, and psychiatric readmissions substance use disorder moderates effects. Design, Setting, Participants This randomized clinical trial compared (n = 106) plus inpatients 94) at a private hospital in Connecticut. Follow-up assessments were completed monthly 6 months postdischarge. enrolled January 2020 through February 2023. Inpatients admitted following crisis (past-week attempt or ideation with plan on admission within previous 2 years) included. Medical records consecutive admissions 4137) screened, 213 study eligible randomized, 200 analyzed. A total 114 participants (57.0%) 6-month follow-up assessments. Data medical also obtained follow-up. Intervention Up 4 individual sessions designed inpatients. Main Outcomes Measures attempts assessed via blind interviews record review. Suicidal was self-report. Results The mean (SD) age among analyzed 32.8 (12.6) years; 117 female 83 male. Brief therapy–inpatient reduced the occurrence over by 60% (odds ratio, 0.40; 95% CI, 0.20-0.80; number needed treat, 7) entire patient group, rate 71% (rate 0.29; 0.09-0.90) those without disorder. effect condition less clear, although post hoc analyses indicated severe vs 1 Conclusions Relevance reattempts when added usual. Substance moderated treatment’s readmission rates. Treatment effects clear. Implementation research facilitate dissemination. Additional optimize outcomes individuals disorders. Trial Registration ClinicalTrials.gov Identifier: NCT04168645

Language: Английский

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Suicide ideation and male-female differences in major depressive disorder

International Journal of Psychiatry in Clinical Practice, Journal Year: 2024, Volume and Issue: 28(1), P. 53 - 62

Published: March 1, 2024

Objective This study aimed to explore male-female differences in suicide ideation (SI) and risk factors major depressive disorder (MDD).

Language: Английский

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A machine learning analysis of suicidal ideation and suicide attempt among U.S. youth and young adults from multilevel, longitudinal survey data

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 24, 2025

To investigate individual, interpersonal, health system, and community factors associated with suicidal ideation (SI) attempts (SA). Utilizing nationally representative data from the National Longitudinal Study of Adolescent to Adult Health (7th-12th graders in 1994-95 followed >20 years until 2016-18, N=18,375), least absolute shrinkage selector operator (LASSO) regression determined multilevel predictors SA SI. Models comprised full diagnosis subgroups (ADD/ADHD, depression, PTSD, anxiety, learning disabilities [LD]). Approximately 2.48% 8.97% reported SI, respectively. Over 25% had 20.98% 6.42% 4.55% ADD/ADHD, 2.50% LD. LASSO identified 20 21 Individual-level SI included educational attainment, substance use, PTSD. Interpersonal-level social support, household size, parental education, while system-level care receipt, insurance, counseling. The strongest associations were among individual-level by interpersonal system factors. distinct across diagnostic highlight importance targeted, subgroup-specific suicide prevention interventions. These findings emphasize value precise, data-driven approaches for diverse populations individuals life-course.

Language: Английский

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Use of gabapentinoid treatment and the risk of self-harm: population based self-controlled case series study

BMJ, Journal Year: 2025, Volume and Issue: 389, P. e081627 - e081627

Published: April 30, 2025

To estimate the effect of gabapentinoid treatment on self-harm. A population based self-controlled case series study. UK Clinical Practice Research Datalink Aurum database linked to Hospital Episode Statistics and Office for National databases. 10 002 adults (aged ≥18 years), with prescriptions, who had an incident event self-harm between 1 January 2000 31 December 2020. Individual censoring occurred date epilepsy, substance misuse, or cancer diagnosis. Crude incidence rates in different risk periods: 90 days before treatment, period, 14 after periods, reference periods were calculated. Conditional Poisson regression derived rate ratio 95% confidence intervals (CIs) evaluate compared period each individual. 503 597 individuals received prescriptions included analysis. The per 100 person years was 16.79 (95% CI 16.65 16.92) 9.66 (9.62 9.70) 29.60 (29.09 30.11) 6.75 (6.74 6.77) period. results yielded increased during day adjusted 1.69 1.55 1.85). spline analysis showed that declined gradually around time initiation returned level (adjusted 1.06 (0.98 1.13)). Adjusted within cessation (3.02 (2.53 3.60)). findings remained consistent throughout a subgroups sensitivity analyses. association gabapentinoids seems be multifaceted: elevated is present which persists initial phase rises again shortly discontinuation. These do not support direct but underscore necessity close patient monitoring journey.

Language: Английский

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Suicide, neuroinflammation and other physiological alterations

European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2023, Volume and Issue: 274(5), P. 1037 - 1049

Published: March 13, 2023

Abstract Suicide is considered one of the major public health problems worldwide, being second leading cause death in 15–29 age group. It estimated that every 40s someone world commits suicide. The social taboo surrounding this phenomenon as well fact suicide prevention measures currently fail to avoid deaths from cause, means more research needed understand its mechanisms. present narrative review on tries point out several important aspects, such risk factors or dynamics suicide, current findings field physiology could offer advances understanding Subjective scales and questionnaires are not effective alone, whereas objective can be addressed physiology. Thus, an increased neuroinflammation people who take their own lives has been found, with increase inflammatory markers interleukin-6 other cytokines plasma cerebrospinal fluid. Also, hyperactivity hypothalamic–pituitary–adrenal axis a decrease serotonin vitamin D levels seems also involved. In conclusion, help which trigger dying by pointing those alterations occur body when attempt commit succeeds taking life. There need for multidisciplinary approaches address raise awareness relevance problem causes thousands year.

Language: Английский

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Heterogeneity in the Course of Suicidal Ideation and its Relation to Suicide Attempts in First-Episode Psychosis: A 5-Year Prospective Study

The Canadian Journal of Psychiatry, Journal Year: 2023, Volume and Issue: 68(11), P. 850 - 859

Published: April 18, 2023

Although the risk of suicide is high in first-episode psychosis (FEP), little known about course suicidal ideation and its relation to attempts. Therefore, we aimed identify 5-year trajectories associated factors FEP compare how attempts were distributed across these identified trajectories.This prospective study assessed ideation, potentially through research interviews, chart review coroners' reports 382 patients [mean age = 23.53 (SD 3.61)] admitted 2 early services Montreal, Canada. Trajectories using a semiparametric mixture model, with multinomial logistic regression.Three identified: low decreasing (n 325, 85.08%); decline, then increasing 30, 7.85%), persistent 27, 7.07%). Suicidal prior admission (OR 2.85, 95% CI, 1.23 6.63, P < 0.05) cocaine use disorder 6.78, 1.08 42.75, trajectory. Persons 4.33, 1.66 11.29, 8.18, 2.39 27.97, 0.001) alcohol 3.63, 1.4 9.42, more likely belong trajectory, attempt during follow-up.Our highlights heterogeneity over 5 years importance ongoing assessment patients, particularly for who persistently report as they are likelier engage Patients or should be targeted prevention interventions from phase follow-up. Given small number persons wide CIs some factors, larger studies however needed further characterize belongs each group.

Language: Английский

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Rising Rates of Suicidal Behaviors and Large Unmet Treatment Needs Among US Adults With a Major Depressive Episode, 2009 to 2020

Mayo Clinic Proceedings, Journal Year: 2023, Volume and Issue: 98(7), P. 969 - 984

Published: July 1, 2023

Language: Английский

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Childhood sexual abuse and suicide attempts in patients with substance use disorders: The mediating role of emotion dysregulation

Child Abuse & Neglect, Journal Year: 2024, Volume and Issue: 151, P. 106731 - 106731

Published: March 19, 2024

Language: Английский

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Female Patients Show a Larger Reduction in Suicidal Ideation in Inpatient Addiction Treatment Than Male Patients: Results of a Single-Center Observational Study

Substance Abuse and Rehabilitation, Journal Year: 2024, Volume and Issue: Volume 15, P. 31 - 42

Published: March 1, 2024

Background: Substance use disorders (SUD) are prevalent worldwide. Among other associated health problems, patients with SUD at an increased risk of dying suicide, females displaying even higher than males. Therefore, the aim this study was to conduct a gender-sensitive evaluation changes in suicidal ideation during multimodal inpatient treatment hospital facility specialized treating addiction. Methods: A total 694 (68.2% male) completed routine assessment including ideation, abstinence confidence, impulsivity, emotion regulation, self-efficacy and autonomy joy both before (T1) end (T2) treatment. Mean were evaluated repeated measures MANOVAs. Results: Before treatment, n=127 (18.3%) respondents reported which reduced n=72 (10.4%) by female patients, change compared from T1 T2 (21.7% vs 7.7%) significantly among male (T1: 16.7%%, T2: 11.6%; p=0.040). Generally, worse symptoms scores slightly numbers thoughts baseline (effect sizes ranging η²=.008 – 0.044). While genders profited generally showed larger improvements male. Discussion: Our underscores beneficial effect addiction-specialized on ideation. Additionally, we found substantial gender effect: while more distressed they also symptom reduction This result highlights need perform research develop programs. Keywords: addiction, therapy, alcohol, drugs, medicine

Language: Английский

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Predictors of suicidal behaviors among school-going adolescents: a cross sectional study in Indonesia

Middle East Current Psychiatry, Journal Year: 2024, Volume and Issue: 31(1)

Published: May 23, 2024

Abstract Background Adolescents are a high-risk age group for committing suicide, and the risk substantially increases from early to late adolescence. Adolescence also serves as critical time period detection intervention prevent suicidal behaviors. This study aimed assess prevalence of suicidality identify significant predictors among adolescents. Methods A cross-sectional observational was conducted between January-December 2023. aged 14–18 years old ( n = 2317) were consecutively recruited 15 high schools across four provinces on Java Island in Indonesia. Self-reported validated instruments Indonesian used sociodemographic profiles, self-esteem (RSES), hopelessness (BHS), loneliness (ULS-3), perceived social support (MSPSS), depression (PHQ-9), resilience (CD-RISC-10), (SBQ-R). With adjusted odds ratio (AOR) 95% confidence interval (CI), binary logistic regression analysis determine suicidality. Results The lifetime suicide ideation 26.5%, plans 18.2%, threat 14.1%, attempt 4.4%. 12-month 43.1%. following variables identified significantly associated with p < 0.05): female students (AOR 1.912; 95%CI:1.507–2.425), chronic illness 2.886; 95%CI:1.545–5.389), low 1.347; 95%CI:1.036–1.750), 2.020; 95%CI:1.578–2.585), family 3.532; 95%CI:2.486–5.017), 1.611; 95%CI:1.211–2.143), 4.882; 95%CI 3.861–6.175), 1.602; 95%CI:1.154–2.224). Nagelkerke R square 0.364 indicating model explained 36.4% variance Conclusions Our revealed several adolescents which can be targeted develop prevention strategies.

Language: Английский

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