A Novel Packaging of the MEMS Gas Sensors Used for Harsh Outdoor and Human Exhale Sampling Applications DOI Creative Commons

Lung-Tai Chen,

Chinsheng Chang,

Liangju Chien

et al.

Sensors, Journal Year: 2023, Volume and Issue: 23(11), P. 5087 - 5087

Published: May 26, 2023

Dust or condensed water present in harsh outdoor high-humidity human breath samples are one of the key sources that cause false detection Micro Electro-Mechanical System (MEMS) gas sensors. This paper proposes a novel packaging mechanism for MEMS sensors utilizes self-anchoring to embed hydrophobic polytetrafluoroethylene (PTFE) filter into upper cover sensor packaging. approach is distinct from current method external pasting. The proposed successfully demonstrated this study. test results indicate innovative with PTFE reduced average response value humidity range 75~95% RH by 60.6% compared without filter. Additionally, passed High-Accelerated Temperature and Humidity Stress (HAST) reliability test. With similar sensing mechanism, embedded can be further employed application exhalation-related, such as coronavirus disease 2019 (COVID-19), screening.

Language: Английский

A review: Progress and trend advantage of dopamine electrochemical sensor DOI
Abdul Karim, M. Yasser, Ahyar Ahmad

et al.

Journal of Electroanalytical Chemistry, Journal Year: 2024, Volume and Issue: 959, P. 118157 - 118157

Published: March 11, 2024

Language: Английский

Citations

21

Enzymatic Electrochemical Biosensors for Neurotransmitters Detection: Recent Achievements and Trends DOI Creative Commons
Zina Fredj, Baljit Singh, Mohamed Bahri

et al.

Chemosensors, Journal Year: 2023, Volume and Issue: 11(7), P. 388 - 388

Published: July 12, 2023

Neurotransmitters (NTs) play a crucial role in regulating the behavioral and physiological functions of nervous system. Imbalances concentrations NT have been directly linked to various neurological diseases (e.g., Parkinson’s, Huntington’s, Alzheimer’s disease), addition multiple psychotic disorders such as schizophrenia, depression, dementia, other neurodegenerative disorders. Hence, rapid real-time monitoring NTs is utmost importance comprehending identifying Among different sensing techniques, electrochemical biosensors garnered significant interest due their ability deliver fast results, compatibility for miniaturization portability, high sensitivity, good controllability. Furthermore, utilization enzymes recognition elements biosensing design has renewed attention unique advantages catalytic biorecognition coupled with simultaneous signal amplification. This review paper primarily focuses on covering recent advances enzymatic detection NTs, encompassing sensors, electrode materials, electroanalytical techniques. Moreover, we shed light applications enzyme-based complex matrices vivo monitoring. Despite numerous biosensors, there are still challenges that need be addressed, which thoroughly discussed this paper. Finally, also presents an outlook future perspectives opportunities development detection.

Language: Английский

Citations

26

High Accuracy of Clinical Verification of Electrohydrodynamic-Driven Nanobox-on-Mirror Platform for Molecular Identification of Respiratory Viruses DOI
Junrong Li, Rui Guan, Alain Wuethrich

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(11), P. 4495 - 4504

Published: March 6, 2024

The molecular detection of multiple respiratory viruses provides evidence for the rational use drugs and effective health management. Herein, we developed tested clinical performance an electrohydrodynamic-driven nanobox-on-mirror platform (E-NoM) parallel, accurate, sensitive four viral antigens. E-NoM uses gold–silver alloy nanoboxes as core material with deposition a silver layer shell on surfaces to amplify enable reproducible Raman signal readout that facilitates accurate detection. Additionally, employs gold microelectrode arrays mirror electrohydrodynamics manipulate fluid flow enhance interactions improved biosensing response. presence antigens binds nanobox-based core–shell nanostructure creates nanocavity extremely strong "hot spots" benefit analysis. Significantly, in large cohort 227 patients, designed demonstrates capability screening infection achieved specificity, sensitivity, accuracy 100.0, 96.48, 96.91%, respectively. It is anticipated can find position usage disease diagnosis.

Language: Английский

Citations

14

Nanomaterial-based electrochemical chemo(bio)sensors for the detection of nanoplastic residues: trends and future prospects DOI Creative Commons
Siwar Jebril, Zina Fredj, Ayman Ali Saeed

et al.

RSC Sustainability, Journal Year: 2024, Volume and Issue: 2(4), P. 832 - 851

Published: Jan. 1, 2024

Nanoplastic residues in our aquatic ecosystems poses a serious global concern which needs effective monitoring to implement actions and control measures. Electrochemical chemo(bio)sensors emerge as promising tool for their detection protect water environmental resources.

Language: Английский

Citations

9

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences DOI Creative Commons
Vishal Chaudhary,

Lucky Lucky,

Harsh Sable

et al.

Small Structures, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

To effectively address crisis emergence of new virus such as monkeypox, a collective and collaborative effort between scientists, engineers, innovators, artists from all ages, regions, diverse fields is required. This review explores holistic approach to addressing the monkeypox by integrating nanobiosensors, artificial intelligence, visual arts, humanities, social sciences. Traditional diagnostic methods are often limited time, accessibility, accuracy, but advancement point‐of‐care smart nanobiosensors offers promising shift toward rapid, precise, accessible diagnostics. They enhance ability screen, diagnose, monitor infections efficiently, contributing better disease management. Beyond technological innovation, essential role sciences in fostering public engagement, understanding, acceptance tools emphasized. Visual arts can illustrate scientific concepts, making them more relatable, while storytelling through various media reduce stigma promote preventive measures. Social provide insights into cultural attitudes, behaviors, health challenges, ensuring that solutions integrated communities. By combining these disciplines, this presents comprehensive framework for resilient global system aligns with One Health principles, emphasizing interconnectedness human, animal, environmental health.

Language: Английский

Citations

1

Biosensors for waterborne virus detection: Challenges and strategies DOI Creative Commons
Xixi Song, Zina Fredj, Yuqiao Zheng

et al.

Journal of Pharmaceutical Analysis, Journal Year: 2023, Volume and Issue: 13(11), P. 1252 - 1268

Published: Aug. 31, 2023

Waterborne viruses that can be harmful to human health pose significant challenges globally, affecting care systems and the economy. Identifying these waterborne pathogens is essential for preventing diseases protecting public health. However, handling complex samples such as wastewater challenging due their dynamic composition ultralow concentration of target analytes. This review presents a comprehensive overview latest breakthroughs in virus biosensors. It begins by highlighting several promising strategies enhance sensing performance optical electrochemical biosensors samples. These include optimizing bioreceptor selection, transduction elements, signal amplification, integrated systems. Furthermore, insights gained from biosensing are applied improve wastewater, with particular focus on sampling sample pretreatment dispersion characteristics wastewater. suggests implementing system integrates entire detection process high-accuracy analysis could monitoring. findings provide valuable improving effectiveness detection, which have implications environmental management.

Language: Английский

Citations

18

Optical biosensing of monkeypox virus using novel recombinant silica-binding proteins for site-directed antibody immobilization DOI Creative Commons
Xixi Song, Ying Tao, Sumin Bian

et al.

Journal of Pharmaceutical Analysis, Journal Year: 2024, Volume and Issue: 14(10), P. 100995 - 100995

Published: May 7, 2024

The efficient immobilization of capture antibodies is crucial for timely pathogen detection during global pandemic outbreaks. Therefore, we proposed a silica-binding protein featuring core functional domains (cSP). It comprises peptide with tag designed to adhere silica surfaces and tandem G fragments (2C2) effective antibody capture. This innovation facilitates precise site-directed onto surfaces. We applied cSP silica-coated optical fibers, creating fiber-optic biolayer interferometer (FO-BLI) biosensor capable monitoring the monkeypox virus (MPXV) A29L in spiked clinical samples rapidly detect MPXV. cSP-based FO-BLI MPXV demonstrated limit (LOD) 0.62 ng/mL buffer, comparable 0.52 LOD achieved using conventional streptavidin (SA)-based biosensor. Furthermore, it LODs 0.77 serum 0.80 saliva, exhibiting no cross-reactivity other viral antigens. process was completed within 14 min. further multi-virus strategy detecting various strains, such as MPXV, latest coronavirus disease (COVID) variants, influenza A protein, extend its versatility. cSP-modified has high potential accurately antigens, making valuable contributions epidemiological studies.

Language: Английский

Citations

8

Advancements and emerging technologies in biosensors for rapid and accurate virus detection DOI
Giovanna Marrazza, Murugan Ramalingam,

Abinaya Jaisankar

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 172, P. 117609 - 117609

Published: Feb. 20, 2024

Language: Английский

Citations

6

MXene-based biosensors for selective detection of pathogenic viruses and bacteria DOI
Serap Sezen, Atefeh Zarepour, Ali Zarrabi

et al.

Microchemical Journal, Journal Year: 2023, Volume and Issue: 193, P. 109258 - 109258

Published: Aug. 26, 2023

Language: Английский

Citations

14

Design and synthesis of bioinspired nanomaterials for biomedical application DOI
Kai Tang,

Jianmin Xue,

Yufang Zhu

et al.

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2023, Volume and Issue: 16(1)

Published: July 2, 2023

Abstract Natural materials and bioprocesses provide abundant inspirations for the design synthesis of high‐performance nanomaterials. In past several decades, bioinspired nanomaterials have shown great potential in application biomedical fields, such as tissue engineering, drug delivery, cancer therapy, so on. this review, three types strategies nanomaterials, that is, inspired by natural structures, biomolecules, bioprocesses, are mainly introduced. We summarize discuss concepts approaches various along with their specific roles applications. Additionally, we challenges development mechanical failure wet environment, limitation scale‐up fabrication, lack deep understanding biological properties. It is expected clinical translation will be further promoted under cooperation interdisciplinary subjects future. This article categorized under: Implantable Materials Surgical Technologies > Nanomaterials Implants Therapeutic Approaches Drug Discovery Emerging

Language: Английский

Citations

13