Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

Abstract Precise targeted delivery of antibiotics to infected sites is crucial for enhancing therapeutic efficacy and minimizing side effects. In this work, we present magnetic hydrogel‐based microrobots active antibiotic achieve bacterial elimination. These comprise a poly(acrylic acid‐co‐acrylamide) hydrogel microspheres encapsulating Fe 3 O 4 nanoparticle chains. The scaffold offers abundant spaces binding high‐capacity loading vancomycin via electrostatic interactions. embedded nanochains enable propulsion. Under rotating field ( H r t )), the can actively deliver their swarming motions, then eliminate bacteria (e.g., Staphylococcus aureus ) utilizing sustainable release on site. hold great promise as motile antibacterial platform treat infectious diseases.

Language: Английский