Surface-functionalized magnetic nanomaterials for the diagnosis and targeted therapy against cancer DOI
Somayeh Sadighian, Morteza Abazari,

Fatemeh Hakimi

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 569 - 607

Published: Jan. 1, 2025

Language: Английский

Label-free and ultrasensitive electrochemical cotinine sensing based on bio-modified magnetic nanoparticles DOI
Muhammet Aydın, Elif Burcu Aydın, Mustafa Kemal Sezgintürk

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 408, P. 135476 - 135476

Published: Feb. 10, 2024

Language: Английский

Citations

5

The role of acoustofluidics and microbubble dynamics for therapeutic applications and drug delivery DOI Creative Commons
S. Ilke Kaykanat, A. Kerem Uğuz

Biomicrofluidics, Journal Year: 2023, Volume and Issue: 17(2)

Published: March 1, 2023

Targeted drug delivery is proposed to reduce the toxic effects of conventional therapeutic methods. For that purpose, nanoparticles are loaded with drugs called nanocarriers and directed toward a specific site. However, biological barriers challenge convey target site effectively. Different targeting strategies nanoparticle designs used overcome these barriers. Ultrasound new, safe, non-invasive method, especially when combined microbubbles. Microbubbles oscillate under effect ultrasound, which increases permeability endothelium, hence, uptake Consequently, this new technique reduces dose avoids its side effects. This review aims describe types critical features acoustically driven microbubbles focusing on biomedical applications. The theoretical part covers historical developments in microbubble models for different conditions: an incompressible compressible medium bubbles encapsulated by shell. current state possible future directions discussed.

Language: Английский

Citations

12

Magnetic Nanoparticles as Mediators for Magnetic Hyperthermia Therapy Applications: A Status Review DOI Creative Commons
Miloš Beković, Irena Ban,

Miha Drofenik

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(17), P. 9548 - 9548

Published: Aug. 23, 2023

This concise review delves into the realm of superparamagnetic nanoparticles, specifically focusing on Fe2O3, Mg1+xFe2−2xTixO4, Ni1−xCux, and CrxNi1−x, along with their synthesis methods applications in magnetic hyperthermia. Remarkable advancements have been made controlling size shape these achieved through various techniques such as coprecipitation, mechanical milling, microemulsion, sol–gel synthesis. Through this review, our objective is to present outcomes diverse methods, surface treatment properties, Curie temperature, elucidate impact heating efficiency when subjected high-frequency fields.

Language: Английский

Citations

12

Nanohybrid Based on (Mn, Zn) Ferrite Nanoparticles Functionalized With Chitosan and Sodium Alginate for Loading of Curcumin Against Human Breast Cancer Cells DOI Creative Commons
Fatemeh Ahmadi, Majid Saeedi, Jafar Âkbari

et al.

AAPS PharmSciTech, Journal Year: 2023, Volume and Issue: 24(8)

Published: Nov. 7, 2023

This study reports on the synthesis of Mn1 - xZnxFe2O4 (Mn, Zn ferrite) magnetic nanoparticles (MNPs) as drug delivery carriers for effective therapeutic outcomes. The MNPs were prepared using coprecipitation method, and their properties investigated based composition. Among compositions tested, Mn0.8Zn0.2Fe2O4 exhibited superparamagnetic with a saturation magnetization moment 34.6 emu/g at room temperature (25°C). To enhance water solubility curcumin (Cur), known its hydrophobic nature, it was successfully loaded onto alginate (Alg)/chitosan (Chit)@Mn0.8Zn0.2Fe2O4 (NPs). nanocomposite characterized by field emission scanning electron microscopy (FE-SEM) which revealed particle size approximately 20 nm. crystalline structure NPs analyzed X-ray diffraction, while Fourier-transform infrared (FTIR), energy-dispersive X-ray, map analysis techniques employed further characterization. In terms release, there an initial burst release Cur (around 18%) within first hour, followed slower (approximately 61%) over next 36 h. anti-tumor Cur-loaded evaluated Methyl Thiazol Tetrazolium (MTT) assay quantitative real-time polymerase chain reaction. MTT confirmed higher cytotoxic effect Alg/[email protected] MCF-7 breast cancer cell line compared to free Cur, highlighting significance incorporating into nano-sized carrier systems.

Language: Английский

Citations

11

Surface-functionalized magnetic nanomaterials for the diagnosis and targeted therapy against cancer DOI
Somayeh Sadighian, Morteza Abazari,

Fatemeh Hakimi

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 569 - 607

Published: Jan. 1, 2025

Language: Английский

Citations

0