Journal of Applied Phycology,
Journal Year:
2024,
Volume and Issue:
36(4), P. 1697 - 1708
Published: April 5, 2024
Abstract
The
marine
microalga
Tisochrysis
lutea
is
a
potential
and
sustainable
source
of
bioactive
compounds
such
as
carotenoids
omega-3
fatty
acids.
In
the
present
work,
extraction
fucoxanthin
docosahexaenoic
acid
(DHA),
most
abundant
which
constitutes
polar
lipids
particularly
in
brain,
was
studied
using
advanced
techniques
with
green
bio-based
solvents
compared
to
traditional
hazardous
organic
solvents.
experimental
design
maximize
lipid
yield
by
ultrasound-assisted
(UAE)
developed,
choosing
factors
percentage
solvent
(0,
50
100%
2-methyl-tetrahydrofuran
or
2-methyloxolane
(2-me-THF)
ethanol),
time
(20,
30
40
min)
temperature
(40,
60
ºC).
highest
yields
were
obtained
ethanol
solvent.
Nevertheless,
interesting
extracts
based
on
their
chemical
composition
when
presence
2-me-THF
mixture
greater
than
that
ethanol.
Through
analytical
HPLC-ELSD/DAD
GC-MS
well
spectrophotometric
techniques,
contents
lipids,
acids,
total
quantified.
addition,
antioxidant
capacity
different
selected
studied,
being
once
again
those
extracted
amounts
due
its
selectivity
enriched
high-added
value
bioactives,
mainly
DHA.
Therefore,
it
shown
importance
an
technique
together
use
not
only
develop
procedures
are
agreement
Green
Chemistry
but
also
preserve
bioactivity.
Applied Sciences,
Journal Year:
2022,
Volume and Issue:
12(4), P. 1924 - 1924
Published: Feb. 12, 2022
Nowadays,
microalgae
and
cyanobacteria
have
become
a
promising
sustainable
source
of
useful
products,
thanks
to
their
richness
in
bioactive
metabolites
high
value
(antibiotics,
toxins,
pharmaceutically
active
compounds,
plant
growth
regulators,
others).
These
photoautotroph
microorganisms
generate
biomass
using
photosynthesis.
This
review,
which
distinguishes
Cyanobacteria,
often
called
blue-green
microalgae,
aims
present
classification
taxonomic
diversity
as
the
ecological
niches
occupied
by
them.
In
addition,
usages
open
ponds
photobioreactors
produce
various
Cyanobacteria
strains
high-value
compounds
from
these
are
summarized.
Finally,
numerous
commercial
applications
phytoplanktons
different
fields,
such
food,
dietary
supplements,
feed,
cosmetic,
biofuel
applications,
reviewed.
Photochemical & Photobiological Sciences,
Journal Year:
2023,
Volume and Issue:
22(8), P. 1733 - 1789
Published: April 10, 2023
Abstract
Phycobiliproteins,
carotenoids
and
fucoxanthin
are
photosynthetic
pigments
extracted
from
microalgae
cyanobacteria
with
great
potential
biotechnological
applications,
as
healthy
food
colorants
cosmetics.
Phycocyanin
possesses
a
brilliant
blue
color,
fluorescent
properties
making
it
useful
reagent
for
immunological
essays.
The
most
important
source
of
phycocyanin
is
the
cyanobacterium
Arthrospira
platensis,
however,
recently,
Rhodophyta
Galdieria
sulphuraria
has
also
been
identified
such.
main
obstacle
to
commercialization
represented
by
its
chemical
instability,
strongly
reducing
shelf-life.
Moreover,
high
level
purity
needed
pharmaceutical
applications
requires
several
steps
which
increase
both
production
time
cost.
Microalgae
(
Chlorella
,
Dunaliella
Nannochloropsis
Scenedesmus
)
produce
light
harvesting
carotenoids,
able
manage
oxidative
stress,
due
their
free
radical
scavenging
properties,
makes
them
suitable
use
natural
antioxidants.
Many
studies
focused
on
selection
promising
strains
producing
valuable
extraction
purification.
Among
produced
marine
microalgae,
abundant,
representing
more
than
10%
total
carotenoids.
Despite
abundance
diversity
only
few
species
have
studied
commercial
production,
relevant
being
Phaeodactylum
tricornutum
.
Due
antioxidant
activity,
can
bring
various
benefits
prevention
treatment
lifestyle-related
diseases.
In
this
review,
we
update
results
achieved
in
extraction,
purification,
these
pigments,
motivating
cultivation
pigments.
Graphical
abstract
Plants,
Journal Year:
2021,
Volume and Issue:
10(5), P. 836 - 836
Published: April 21, 2021
Microalgae
are
multifaceted
photosynthetic
microorganisms
with
emerging
business
potential.
They
present
ubiquitously
in
terrestrial
and
aquatic
environments
rich
species
diversity
capable
of
producing
significant
biomass.
Traditionally,
microalgal
biomass
is
being
used
as
food
feed
many
countries
around
the
globe.
The
production
microalgal-based
bioactive
compounds
at
an
industrial
scale
through
biotechnological
interventions
gaining
interest
more
recently.
review
provides
a
detailed
overview
key
algal
metabolites,
which
plays
crucial
role
nutraceutical,
functional
foods,
animal/aquaculture
industries.
Bioactive
microalgae
known
to
exhibit
antioxidant,
antimicrobial,
antitumor,
immunomodulatory
effects
were
comprehensively
reviewed.
potential
biological
extracts
against
human
pathogens
also
discussed.
Further,
current
technologies
involved
upstream
downstream
bioprocessing
including
cultivation,
harvesting,
cell
disruption
documented.
Establishing
alternative
supplement
would
complement
sustainable
environmental
requirements
framework
health
well-being.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(24), P. 8852 - 8852
Published: Dec. 13, 2022
Microalgae
are
photosynthetic,
eukaryotic
organisms
that
widely
used
in
the
industry
as
cell
factories
to
produce
valuable
substances,
such
fatty
acids
(polyunsaturated
(PUFAs)
eicosapentaenoic
acid
(EPA)
and
docosahexaenoic
(DHA)),
sterols
(sitosterol),
recombinant
therapeutic
proteins,
carbohydrates,
vitamins,
phenolic
compounds
(gallic
acid,
quercetin),
pigments
(β-carotene,
astaxanthin,
lutein).
Phenolic
carotenoids,
including
those
extracted
from
microalgae,
possess
beneficial
bioactivities
antioxidant
capacity,
antimicrobial
immunomodulatory
activities,
direct
health-promoting
effects,
which
may
alleviate
oxidative
stress
age-related
diseases,
cardiovascular
diseases
or
diabetes.
The
production
of
microalgal
metabolites
can
be
modified
by
using
abiotic
stressors,
light,
salinity,
nutrient
availability,
xenobiotics
(for
instance,
phytohormones).
Molecules,
Journal Year:
2022,
Volume and Issue:
27(4), P. 1178 - 1178
Published: Feb. 9, 2022
An
antiviral
agent
is
urgently
needed
based
on
the
high
probability
of
emergence
and
re-emergence
future
viral
disease,
highlighted
by
recent
global
COVID-19
pandemic.
The
may
be
seen
in
discovery
Alpha,
Beta,
Gamma,
Delta,
recently
discovered
Omicron
variants
SARS-CoV-2.
need
for
strategies
besides
testing
isolation,
social
distancing,
vaccine
development
clear.
One
includes
searching
an
that
provides
effective
results
without
toxicity,
which
well-presented
significant
carrageenan
nasal
spray
providing
efficacy
against
human
coronavirus-infected
patients.
As
primary
producer
sulfated
polysaccharides,
marine
plants,
including
macro-
microalgae,
offer
versatility
culture,
production,
post-isolation
obtaining
agent.
Therefore,
this
review
will
describe
attempt
to
highlight
search
practical
safe
agents
from
algal-based
polysaccharides
unveil
their
features
development.
