Facile Immunoassay Constructed by Gold Nanostar-Labeled Rabbit-AFP Antibody and Gold Nanoparticle-Conjugated Goat Anti-Rabbit IgG
Nanomaterials,
Journal Year:
2025,
Volume and Issue:
15(8), P. 612 - 612
Published: April 16, 2025
Simple
and
accurate
analysis
of
cancer-related
biomarkers
is
very
important
for
disease
screening
auxiliary
diagnosis.
This
study
proposed
a
facile
immunoassay
that
used
gold
nanostar-labeled
rabbit
anti-AFP
as
capture
antibody
nanoparticle-conjugated
goat
anti-rabbit
IgG
an
enhance
the
construction
detection
strategy
AFP
analysis.
Investigations
indicated
50
nm
diameter
GNS-labeled
can
specifically
catch
AFPs
by
direct
profile
or
further
signal
amplification
through
AuNP-tagged
combination.
Results
showed
developed
method
holds
8.6
ng/mL
sensitivity,
20.0–110.0
range,
acceptable
precision
fine
accuracy,
well
favorable
specificity.
application
to
real
serum
determination
are
highly
related
those
ECLIA
(correlation
coefficient
0.931).
The
has
simple-operation
merit
suitable
clinical
large-scale
samples
cancers.
Language: Английский
Nano-foam gold-modified diamond electrochemical aptasensing platform for ultrasensitive monitoring of 17β-estradiol
RSC Advances,
Journal Year:
2025,
Volume and Issue:
15(16), P. 12291 - 12297
Published: Jan. 1, 2025
A
nano-foam
gold/BDD
aptasensor
achieves
femtomolar
17β-estradiol
detection
in
water
via
nanostructural
and
molecular
synergy,
enabling
selective
environmental
monitoring.
Language: Английский