Closed-loop brain training: the science of neurofeedback

Nature reviews. Neuroscience, Journal Year: 2016, Volume and Issue: 18(2), P. 86 - 100

Published: Dec. 22, 2016

Language: Английский

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Neurofeedback with fMRI: A critical systematic review

NeuroImage, Journal Year: 2017, Volume and Issue: 172, P. 786 - 807

Published: Dec. 27, 2017

Language: Английский

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Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation

Frontiers in Human Neuroscience, Journal Year: 2018, Volume and Issue: 12

Published: March 29, 2018

This review focuses on the cognitive neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) based functional magnetic resonance imaging (fMRI) studies and recent clinically relevant applications such as fMRI-based diagnostic classification or neuromodulation therapies targeting fMRI deficits with neurofeedback (NF) brain stimulation. Meta-analyses executive functions (EFs) show that ADHD patients have cognitive-domain dissociated complex multisystem impairments in several right left hemispheric dorsal, ventral medial fronto-cingulo-striato-thalamic fronto-parieto-cerebellar networks mediate control, attention, timing working memory (WM). There is furthermore emerging evidence for abnormalities orbital ventromedial prefrontal limbic areas motivation emotion control. In addition, poor deactivation default mode network (DMN) suggests an abnormal interrelationship between hypo-engaged task-positive poorly "switched off" hyper-engaged task-negative networks, both which are related to impaired cognition. Translational still its infancy. Pattern recognition analyses attempted provide using data respectable accuracies over 80%. Necessary replication studies, however, outstanding. Brain stimulation has been tested heterogeneously designed, small numbered proof concept key frontal ADHD. Transcranial direct current (tDCS) appears be promising improve symptoms some but larger clinical trials repeated without training needed test efficacy potential costs non-targeted functions. Only three piloted NF dysfunctions near-infrared spectroscopy, two ones finding improvements cognition symptoms, which, were not superior active control conditions, suggesting placebo effects. Neurotherapeutics seems attractive due their safety longer-term neuroplastic effects, drugs cannot offer. However, they need thoroughly short- individualized treatment.

Language: Английский

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Control freaks: Towards optimal selection of control conditions for fMRI neurofeedback studies

NeuroImage, Journal Year: 2018, Volume and Issue: 186, P. 256 - 265

Published: Nov. 10, 2018

Language: Английский

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Targeting the affective brain—a randomized controlled trial of real-time fMRI neurofeedback in patients with depression

Neuropsychopharmacology, Journal Year: 2018, Volume and Issue: 43(13), P. 2578 - 2585

Published: June 23, 2018

Functional magnetic resonance imaging neurofeedback (fMRI-NF) training of areas involved in emotion processing can reduce depressive symptoms by over 40% on the Hamilton Depression Rating Scale (HDRS). However, it remains unclear if this efficacy is specific to feedback from emotion-regulating regions. We tested a single-blind, randomized, controlled trial upregulation (NFE) yields superior compared control region activated visual scenes (NFS). Forty-three moderately severely depressed medicated patients were randomly assigned five sessions augmentation treatment either NFE or NFS training. At primary outcome (week 12) no significant group mean HDRS difference was found (B = -0.415 [95% CI -4.847 4.016], p 0.848) for 32 completers (16 per group). across groups decreased 43%, and 38% remitted. These improvements lasted until follow-up 18). Both upregulated target regions similar extent. Further, clinical improvement correlated with an increase self-efficacy scores. interpretation limited due lack sham-control group. thus surveyed effects reported accepted therapies depression. Data indicated that our findings exceed expected regression placebo have been drug trials other sham-controlled high-technology interventions. Taken together, we suggest experience successful self-regulation during fMRI-NF may be therapeutic. conclude effective depression, higher provide alternative.

Language: Английский

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Frontal alpha asymmetry neurofeedback for the reduction of negative affect and anxiety

Behaviour Research and Therapy, Journal Year: 2017, Volume and Issue: 92, P. 32 - 40

Published: Feb. 21, 2017

Language: Английский

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Real‐time fMRI neurofeedback in adolescents with attention deficit hyperactivity disorder

Human Brain Mapping, Journal Year: 2017, Volume and Issue: 38(6), P. 3190 - 3209

Published: March 25, 2017

Abstract Attention Deficit Hyperactivity Disorder (ADHD) is associated with poor self‐control, underpinned by inferior fronto‐striatal deficits. Real‐time functional magnetic resonance neurofeedback (rtfMRI‐NF) allows participants to gain self‐control over dysregulated brain regions. Despite evidence for beneficial effects of electrophysiological‐NF on ADHD symptoms, no study has applied the spatially superior rtfMRI‐NF neurotherapy ADHD. A randomized controlled trial tested efficacy right prefrontal cortex (rIFG), a key region that compromised in and upregulated psychostimulants, improvement cognition, inhibitory fMRI activation. To control region‐specificity, an active group received left parahippocampal gyrus (lPHG). Thirty‐one boys were randomly allocated had learn upregulate their target average 11 runs 2 weeks. Feedback was provided through video‐clip rocket be moved up into space. transfer session without feedback learning retention as proximal measure everyday life. Both NF groups showed significant linear activation increases increasing number respective regions reduction symptoms after at 11‐month follow‐up. Only targeting rIFG, however, effect, which correlated symptom reductions, improved trend level sustained attention, increased IFG during task. This proof‐of‐concept demonstrates first time feasibility, safety, shorter‐ longer‐term rIFG adolescents Hum Brain Mapp 38:3190–3209, 2017 . © The Authors Human Mapping Published Wiley Periodicals, Inc.

Language: Английский

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Electrical fingerprint of the amygdala guides neurofeedback training for stress resilience

Nature Human Behaviour, Journal Year: 2018, Volume and Issue: 3(1), P. 63 - 73

Published: Dec. 7, 2018

Language: Английский

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Alpha Synchrony and the Neurofeedback Control of Spatial Attention

Neuron, Journal Year: 2019, Volume and Issue: 105(3), P. 577 - 587.e5

Published: Dec. 4, 2019

Language: Английский

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Assessment of mental stress effects on prefrontal cortical activities using canonical correlation analysis: an fNIRS-EEG study

Biomedical Optics Express, Journal Year: 2017, Volume and Issue: 8(5), P. 2583 - 2583

Published: April 19, 2017

This paper presents an investigation about the effects of mental stress on prefrontal cortex (PFC) subregions using simultaneous measurement functional Near-Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG) signals. The aim is to explore canonical correlation analysis (CCA) technique study relationship among bi-modality signals in assessment, how we could fuse for better accuracy detection. Twenty-five male healthy subjects participated while performing arithmetic task under control (under time pressure with negative feedback) conditions. fusion brain acquired by fNIRS-EEG was performed at feature-level CCA maximizing inter-subject covariance across modalities. result discovered associations modalities estimated components responsible these associations. experiment results showed that experienced this cohort subregion specific localized right ventrolateral PFC subregion. These suggest as a suitable candidate region extract biomarkers performance indicators neurofeedback training coping.

Language: Английский

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