Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney DOI Creative Commons
Mehmet Reşit Taysı

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 10, 2024

Cadmium contamination in aquatic environments poses severe risks to organisms, particularly fish, where cadmium accumulation tissues can lead compromised organ functionality and reproductive issues. The present study aimed assess the effects of (Cd) exposure on key biomarkers oxidative stress, DNA damage, apoptosis, enzyme activity liver kidney rainbow trout (Oncorhynchus mykiss). Specifically, measured 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, caspase-3 activation, acetylcholinesterase (AChE) activity, stress indicators (ONOO

Language: Английский

A review of the neurobehavioural, physiological, and reproductive toxicity of microplastics in fishes DOI Creative Commons
Hasan Arman, Mohamed Hamed, Jabed Hasan

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 282, P. 116712 - 116712

Published: July 15, 2024

Microplastics (MPs) have emerged as widespread environmental pollutants, causing significant threats to aquatic ecosystems and organisms.This review examines the toxic effects of MPs on fishes, with a focus neurobehavioural, physiological, reproductive impacts, well underlying mechanisms toxicity.Evidence indicates that induce range neurobehavioural abnormalities in affecting social interactions cognitive functions.Altered neurotransmitter levels are identified key mechanism driving behavioural alterations following MP exposure.Physiological fishes exposed also reported, including neurotoxicity, immunotoxicity, oxidative stress.These physiological disruptions can compromise individual health organisms.Furthermore, linked exposure discussed, particular emphasis endocrine signaling pathways.These impair success fish species, impacting population numbers.Here we explore critical role mediating after MPs, focusing primarily hypothalamic-pituitary-gonadal axis.Our highlights urgent need for interdisciplinary research efforts aimed at elucidating full extent toxicity its implications ecosystems.Lastly, identify knowledge gaps future research, investigations into transgenerational if any, quantifying synergetic/antagonistic other pollutants.This expanded regarding potential risks wildlife is expected aid policymakers developing mitigation strategies protect species.

Language: Английский

Citations

19

Immunological, neurological, and intestinal changes in red swamp crayfish (Procambarus clarkii) exposed to the combined toxicity of Pyrogallol and microplastics DOI

Mohamed Hamed,

Rashad E.M. Said, Walaa M. Shaalan

et al.

Marine Pollution Bulletin, Journal Year: 2025, Volume and Issue: 213, P. 117641 - 117641

Published: Feb. 8, 2025

Language: Английский

Citations

1

Impacts of Voliam Flexi on Antioxidant Responses, Oxidative Stress, and Histopathological Changes in Juvenile African Catfish (Clarias gariepinus) DOI Creative Commons
Mohamed Hamed,

Hanem Abdel-Tawab,

Mostafa A. Abdel-Maksoud

et al.

Aquaculture Research, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

This study investigated the toxicological impact of Voliam Flexi (containing chlorantraniliprole and thiamethoxam) on juvenile African catfish ( Clarias gariepinus ), a species commonly exposed to pesticides in rice cultivation regions. toxic effects catfish, focusing oxidative stress, antioxidant enzyme disruption, tissue damage at environmentally relevant concentrations. Over 15‐day period, fish were pesticide concentrations applied Egyptian fields, specifically 43.5, 87.5, 175 mg/L. Antioxidant defense mechanisms, including GST (glutathione S‐transferase), SOD (superoxide dismutase), CAT (catalase), TAC (total capacity), measured alongside indicators such as lipid peroxidation (LPX) DNA fragmentation. A dose‐dependent reduction activity an increase observed, with higher leading elevated LPX levels Histopathological evaluations kidney spleen revealed significant degenerative changes, tubular damage, edema, pyknotic nuclei, particularly These findings suggest that poses considerable risks aquatic organisms, disrupting cellular functions, damage. The highlights potential threat runoff biodiversity calls for stricter environmental regulations mitigate these risks.

Language: Английский

Citations

0

Exploring the Coexposure Effects of Pyrogallol and Microplastic on the Red Swamp Crayfish Procambarus clarkii DOI Creative Commons
Rashad E.M. Said, Mohamed Hamed, Walaa M. Shaalan

et al.

Aquaculture Research, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Investigating the impact of two or more toxic chemicals on aquatic organisms is one main objectives toxicological research. Microplastics (MPs) are identified as a carrier vector for other pollutants. Therefore, current study investigated effects both pyrogallol (PG) and MPs, individually in combination, freshwater crayfish ( Procambarus clarkii ). Following 15‐day exposure to 10 mg/L PG and100 MPs their combination (10 + 100 MPs), hemocyte count, hepatopancreatic parameters, antioxidant variables, histopathological markers were all assessed crayfish. The results revealed that potentially combined altered count (including granular semigranular) compared control group (0.001 ≥ p < 0.0001). levels aspartate aminotransferase (AST), alanine (ALT), protein showed significant elevation 0.05) PG–MP‐exposed fish ones. In comparison P. , measured oxidation indicators, superoxide dismutase (SOD), glutathione (GSH), total capacity (TAC), reduction after single > 0.0001), while catalase (CAT) malondialdehyde (MDA) elevated drastically (0.05 histology hepatopancreas has shown many deformities abnormalities individual toxicity, such vacuolations, degraded tubules, eosinophilic deposits, hemocytic infiltrations, aberrant tubules. Accordingly, there synergistic relationship between MP toxicity it crucial routinely check assess discharge waste into waterways.

Language: Английский

Citations

0

The protective effects of dietary microalgae against hematological, biochemical, and histopathological alterations in pyrogallol-intoxicated Clarias gariepinus DOI Creative Commons

Mohamed Hamed,

Nasser S. Abou Khalil, Alshaimaa A. I. Alghriany

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(24), P. e40930 - e40930

Published: Dec. 1, 2024

Language: Английский

Citations

1

Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney DOI Creative Commons
Mehmet Reşit Taysı

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 10, 2024

Cadmium contamination in aquatic environments poses severe risks to organisms, particularly fish, where cadmium accumulation tissues can lead compromised organ functionality and reproductive issues. The present study aimed assess the effects of (Cd) exposure on key biomarkers oxidative stress, DNA damage, apoptosis, enzyme activity liver kidney rainbow trout (Oncorhynchus mykiss). Specifically, measured 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, caspase-3 activation, acetylcholinesterase (AChE) activity, stress indicators (ONOO

Language: Английский

Citations

1