Numerical study of bacteria removal from microalgae solution using an asymmetric contraction-expansion microfluidic device: A parametric analysis approach DOI Creative Commons
Ali Karimi, Mehdi Sattari‐Najafabadi

Heliyon, Journal Year: 2023, Volume and Issue: 9(10), P. e20380 - e20380

Published: Sept. 22, 2023

Microalgae have been remarkably taken into account due to their wide applications in the biopharmaceutical, nutraceutical and bio-energy fields. However, contamination of microalgae with bacteria still appears be a concern, adversely impacting products' quality process efficiency. decontamination conventional techniques is usually expensive time-consuming. Moreover, damage cells highly possible. Asymmetric contraction-expansion microchannels (Asym-CEMCs) are promising passive microfluidic devices that can overcome techniques' drawbacks standing-out features. flexibility Asym-CEMCs performance arising from various tunable geometrical parameters results fact for separating target particle cannot predicted without an investigation. In this work, first time, were numerically studied removal very bacteria, B. subtilis (1 μm), one most popular microalgae, C. vulgaris (5.7 μm). The influences microchannel aspect ratio, length width ratios expansion-to-contraction zones, total flow rate on separation resolution focusing particles investigated by 3D numerical model. ratio had strongest influence Asym-CEMC performance, however, no considerable effect results. A decrease augmented shear-induced lift force Dean drag force, leading significant improvement. was also enhanced increase ratio. Finally, locally optimized 4.7 2.07, respectively, proposed, complete high normalized 0.6. word, tailored dimensions successfully decontaminating bacteria.

Language: Английский

Investigation of kinetic, isotherm and adsorption efficacy of thorium by orange peel immobilized on calcium alginate DOI Creative Commons
Ali A. Gh. Khamseh, Sohrab Ali Ghorbanian, Younes Amini

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: May 24, 2023

Abstract In this research work the thorium uptake on immobilized protonated orange peel was studied in a batch system. The effects of effective parameters such as biosorbent dosage, initial metal ion concentration, and contact time biosorption were analyzed. capacity for at optimal conditions pH 3.8, dosage 8 g/L, concentration 170 mg/L found to be 18.65 mg/g. According results time, process reached equilibrium after around 10 h contact. Investigation kinetics showed that onto follows pseudo-second-order model. Langmuir Freundlich isotherms used model experimental data. better agreement by isotherm. maximum absorption adsorption predicted isotherm 29.58

Language: Английский

Citations

46
Computational fluid dynamics simulation of two-phase flow patterns in a serpentine microfluidic device DOI Creative Commons
Younes Amini, Valiyollah Ghazanfari,

Mehran Heydari

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: June 10, 2023

In the current research work, flow behavior of a liquid-liquid extraction (LLE) process in serpentine microchannel was analyzed. The simulation performed using 3D model and results were found to be consistent with experimental data. impact chloroform water on also examined. data indicate that once aqua organic phases rates are low similar, slug pattern is observed. However, as overall rate raises, transforms into parallel plug or droplet flow. An increment flows while maintaining constant phase transition from either Finally, patterns micro-channel characterized depicted. this study will provide valuable insights two-phase microfluidic devices. This information can used optimize design devices for various applications. Furthermore, demonstrate applicability CFD investigating fluids devices, which cost-effective efficient alternative studies.

Language: Английский

Citations

38
Novel modified probiotic gold nanoparticles loaded with ginsenoside CK exerts an anti-inflammation effect via NF-κB/MAPK signaling pathways DOI Creative Commons
Seung‐Hyun Kim, Rongbo Wang,

Sanjeevram Dhandapani

et al.

Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(4), P. 105650 - 105650

Published: Jan. 24, 2024

Gold nanoparticles (AuNPs) exhibit promising potential as medical materials due to their high biocompatibility, tunable size and shape, excellent drug delivery capabilities, among other unique physicochemical properties. Previous studies have indicated the remarkable anti-inflammatory activity of ginsenoside compound K (CK). However, relatively low bioavailability CK restricts its effective action within biological system. Hence, exploring novel methods based on gold emerges a strategy overcome these challenges in application, thereby enhancing therapeutic effectiveness CK. Probiotic-mediated AuNPs were synthesized using salt lysates Bifidobacterium animalis subsp. lactis. Then, was loaded with form (Bifi-CKAuNPs). The Bifi-CKAuNPs evaluated vitro RAW 264.7 cells vivo mice. NF-κB/ mitogen-activated protein kinases (MAPK) pathway investigated mechanism action. In experiments showed that inhibited activation reactive oxygen species reduced expression iNOS, COX-2, pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) cells. significantly inflammation lung, kidney, liver tissues mice without toxicity. mediated through inhibition NF-κB/MAPK signal transduction, which is well-known critical pathogenesis inflammation. We successfully characterized Bifi-AuNPs, demonstrating potent both vivo. Our results might play key role Bifi-CKAuNPs. These findings underscored significant platform for therapy. observed efficacy cellular animal models, along insights into underlying molecular pathways, positions valuable candidate advancing strategies realm management.

Language: Английский

Citations

10
Investigating the effectiveness of the main channel in microfluidic liquid-liquid extraction process DOI
Farshad Raji,

Amir Kahani,

Mohammadreza Sahabi

et al.

International Communications in Heat and Mass Transfer, Journal Year: 2023, Volume and Issue: 147, P. 106986 - 106986

Published: Aug. 14, 2023

Language: Английский

Citations

22
Microfluidic Devices for Heavy Metal Ions Detection: A Review DOI Creative Commons
M.K. Filippidou, S. Chatzandroulis

Micromachines, Journal Year: 2023, Volume and Issue: 14(8), P. 1520 - 1520

Published: July 28, 2023

The contamination of air, water and soil by heavy metal ions is one the most serious problems plaguing environment. These are characterized a low biodegradability high chemical stability can affect humans animals, causing severe diseases. In addition to typical analysis methods, i.e., liquid chromatography (LC) or spectrometric methods (i.e., atomic absorption spectroscopy, AAS), there need for development inexpensive, easy-to-use, sensitive portable devices detection at point interest. To this direction, microfluidic lab-on-chip (LOC) fabricated with novel materials scalable microfabrication have been proposed as promising approach realize such systems. This review focuses on recent advances used important toxic ions, namely, lead (Pb), mercury (Hg), arsenic (As), cadmium (Cd) chromium (Cr) ions. Particular emphasis given materials, fabrication realization in order provide complete overview existing technology well limitations challenges that should be addressed improve commercial uptake LOC environmental monitoring applications.

Language: Английский

Citations

21
Ce(ΙΙΙ) and La(ΙΙΙ) ions adsorption through Amberlite XAD-7 resin impregnated via CYANEX-272 extractant DOI Creative Commons

Azadeh Yarahmadi,

Mohammad Hassan Khani,

Masoud Nasiri

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: April 28, 2023

The goal of this paper is to investigate the ability Amberlite XAD-7 (AXAD-7) resin impregnated with CYANEX-272 (di-2,4,4-trimethylpentyl phosphonic acid) remove cerium (Ce(ΙΙΙ)) and lanthanum (La(ΙΙΙ)) ions from aqueous solutions in batch scheme. prepared adsorbent material was determined utilizing FTIR, SEM-EDX, BET methods. impact three individual process variable factors involving feed solution pH (2-6), dose (0.05-0.65), temperature (15-55 °C) on simultaneous removal Ce(ΙΙΙ) La(ΙΙΙ) evaluated via response surface methodology (RSM) according central composite design (CCD). modeling adsorption performed using quadratic model a coefficient determination for both ions. optimization data revealed that amount under optimal conditions were 99.75% 69.98%, respectively. Equilibrium kinetic investigations also conducted define performance calculated removal. Various isotherms models such as Langmuir, Freundlich, Temkin, Sips examined at 25 °C analyze equilibrium isotherm data. approach compatible experimental highest capacity 11.873 mg g-1 7.324 g-1, correspondingly. study pseudo-first-order, pseudo-second-order, intraparticle diffusion models(IDMs). Based obtained, fitted well pseudo-second-order rate correlation. According obtained results, removing stability during several adsorption-desorption cycles regeneration excellent metallic recovery.

Language: Английский

Citations

19
Intensification of strontium (II) ion biosorption on Sargassum sp via response surface methodology DOI Creative Commons
Fatemeh Soleymani,

Mohammad Hasan Khani,

H. Pahlevanzadeh

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: April 3, 2023

A batch system was employed to investigate the biosorption of strontium (II) on Sargassum sp. The sp studied with response surface methodology determine combined effect temperature, initial metal ion concentration, biomass treatment, biosorbent dosage and pH. Under optimal conditions, algae's capacity for (initial pH 7.2, concentration 300 mg/l Mg-treated 0.1 g in 100 mL solution) measured at 103.95 mg/g. In our analysis, equilibrium data were fitted Langmuir Freundlich isotherms. Results show that best fit is provided by model. Biosorption dynamics analysis experimental indicated absorbed into algal accordance pseudo-second-order kinetics model well.

Language: Английский

Citations

16
Employing RSM and ANN-based applications for modelling enhanced bacterial cellulose production from pineapple peel waste using Komagateibacter saccharivorans APPK1 DOI
Ajay Patel, Payal Patel,

Manisha Parmar

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 480, P. 148057 - 148057

Published: Dec. 14, 2023

Language: Английский

Citations

16
Ce(III) and La(III) ions adsorption using Amberlite XAD-7 resin impregnated with DEHPA extractant: response surface methodology, isotherm and kinetic study DOI Creative Commons

Azadeh Yarahmadi,

Mohammad Hassan Khani,

Masoud Nasiri

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: June 20, 2023

In this paper, the removal efficiency of Cerium (Ce(ΙΙΙ)) and lanthanum (La(ΙΙΙ)) ions from aqueous solution using Amberlite XAD-7 resin impregnated with DEHPA(XAD7-DEHPA) was studied in batch system. The adsorbent ( XAD7-DEHPA) characterized by SEM-EDX, FTIR BET analysis Techniques. response surface methodology based on central composite design applied to model optimize process evaluate operating parameters like dose (0.05-0.065), initial pH (2-6) temperature (15-55). Variance showed that dose, were most effective adsorption Ce(ΙIΙ)and La(IΙI) respectively. results optimum condition achieved at = 6, amount absorbent equilibrium time equal 0.6 gr 180 min, According results, percentage Ce(ΙIΙ) La(ΙΙΙ) onto aforementioned 99.99% 78.76% Langmuir, Freundlich, Temkin sips isotherm models describe data. From Langmuir (R2 (Ce) 0.999, R2 (La) 0.998) found better correlate experimental rate maximum capacity for both Ce(IΙI) La(III) be 8.28 5.52 mg g-1 kinetic data fitted pseudo-first-order, pseudo-second-order Intra particle diffusion models. Based pseudo-first-order described as well. general, is an solutions due its high ability selectively remove these metals well reusability.

Language: Английский

Citations

14
Intensification of thorium biosorption onto protonated orange peel using the response surface methodology DOI
Ali A. Gh. Khamseh, Younes Amini,

Mohammad Mahdi Shademan

et al.

Chemical Product and Process Modeling, Journal Year: 2023, Volume and Issue: 18(4), P. 657 - 670

Published: March 2, 2023

Abstract In this research work, intensifying the possibility of protonated orange peel to uptake thorium (IV) ions from aqueous solutions in a batch system was investigated and optimized using response surface methodology. The effect three independent process variables including initial concentration, pH, biosorbent dosage assessed based on central composite design. validity quadratic model verified by coefficient determination. optimization results showed that rate under optimal conditions is 183.95 mg/g. modeling experimental data biosorption kinetics are fitted well pseudo-second-order model. According results, reached equilibrium after around 4 h contact. Langmuir isotherm describes well. maximum absorption capacity for adsorption estimated at 236.97 Thermodynamic studies show thermodynamically feasible, spontaneous, endothermic.

Language: Английский

Citations

13