
Vascular Health and Risk Management, Journal Year: 2024, Volume and Issue: Volume 20, P. 493 - 499
Published: Nov. 1, 2024
Non-valvular atrial fibrillation (NVAF) is the most common sustained arrhythmia worldwide, and associated with significant morbidity mortality. Increasing life expectancy, coupled a surge in comorbidity burden, has resulted sharp increase NVAF prevalence over last three decades. Coronary artery disease (CAD) an important clinically relevant risk factor of AF. Concomitant CAD implications for AF management major determinant overall outcomes. Shared factors, pathophysiological basis, heightened thrombogenesis culminating cardiovascular adverse events, highlight close association between two. The clinical course worse when CAD, resulting poor heart rate control, increased propensity to develop stroke myocardial infarction, likelihood acute presentation hemodynamic collapse pulmonary edema, bleeding tendencies, response ablation therapies. Emerging research highlighting role underlying as independent predictor thromboembolic paved way adoption beyond prior infarction into symbol "V" CHA2DS2-VASc score. In our opinion, elderly patients aged >65 years AF, history one or more comorbidities, evidence atherosclerosis other vascular beds should warrant closer look dedicated effort CAD. This would allow holistic comprehensive approach ultimately help reduce burden improve
Language: Английский