Biological Psychology,
Journal Year:
2022,
Volume and Issue:
170, P. 108325 - 108325
Published: March 28, 2022
The
ability
to
sense,
monitor,
and
control
respiration
-
e.g.,
respiratory
interoception
(henceforth,
respiroception)
is
a
core
homeostatic
ability.
Beyond
the
regulation
of
gas
exchange,
enhanced
awareness
sensations
directly
related
psychiatric
symptoms
such
as
panic
anxiety.
Indeed,
chronic
breathlessness
(dyspnea)
associated
with
fourfold
increase
in
risk
developing
depression
anxiety,
breath
key
aspect
many
mindfulness-based
approaches
treatment
mental
illness.
Physiologically
speaking,
accurately
monitor
important
for
optimizing
cardiorespiratory
function
during
athletic
exertion,
can
be
indicator
Given
role
respiroception
physical
health,
it
unsurprising
that
there
increased
interest
quantification
psychophysiology
across
different
perceptual
metacognitive
levels
psychological
hierarchy.
Compared
other
more
popular
modalities
interoception,
cardiac
domain,
are
relatively
few
methods
available
measuring
aspects
respiroception.
Existing
inspiratory
loading
tasks
difficult
administer
frequently
require
expensive
medical
equipment,
or
offer
poor
granularity
their
respiratory-related
To
facilitate
study
respiroception,
we
here
present
new,
fully
automated
computer-controlled
apparatus
psychophysiological
method,
which
flexibly
easily
measure
interoceptive
sensitivity,
bias
metacognition,
little
30
min
testing,
using
easy
make
3D
printable
parts.
Neuroscience & Biobehavioral Reviews,
Journal Year:
2022,
Volume and Issue:
140, P. 104754 - 104754
Published: July 4, 2022
Anxiety
is
often
conceptualised
as
the
prototypical
disorder
of
interoception
(one's
perception
bodily
states).
Whilst
theoretical
models
predict
an
association
between
interoceptive
accuracy
and
anxiety,
empirical
work
has
produced
mixed
results.
This
manuscript
presents
a
pre-registered
systematic
review
(https://osf.io/2h5xz)
meta-analysis
55
studies,
obtained
via
Pubmed
search
on
9th
November
2020,
examining
relationship
state
trait
anxiety
objectively
measured
cardiac
assessed
by
heartbeat
counting
discrimination
tasks.
Potential
moderators
this
-
age,
gender
clinical
diagnoses
participants,
measures
used
study
design
were
also
explored.
Overall,
we
found
no
evidence
for
with
none
factors
examined
moderating
finding.
We
discuss
implications
these
findings
have
future
research,
particular
focus
need
further
investigation
other
facets
interoception.
Nature Metabolism,
Journal Year:
2023,
Volume and Issue:
5(8), P. 1352 - 1363
Published: Aug. 17, 2023
Survival
under
selective
pressure
is
driven
by
the
ability
of
our
brain
to
use
sensory
information
advantage
control
physiological
needs.
To
that
end,
neural
circuits
receive
and
integrate
external
environmental
cues
internal
metabolic
signals
form
learned
associations,
consequently
motivating
adapting
behaviour.
The
dopaminergic
midbrain
plays
a
crucial
role
in
learning
adaptive
behaviour
particularly
sensitive
peripheral
signals,
including
intestinal
peptides,
such
as
glucagon-like
peptide
1
(GLP-1).
In
single-blinded,
randomized,
controlled,
crossover
basic
human
functional
magnetic
resonance
imaging
study
relying
on
computational
model
process
underlying
behavioural
responses,
we
show
reduced
when
sensing
impaired
obesity,
indexed
insulin
sensitivity
(participants:
N
=
30
with
normal
sensitivity;
24
sensitivity).
Treatment
GLP-1
receptor
agonist
liraglutide
normalizes
associations
men
women
obesity.
Collectively,
findings
reveal
activation
modulates
associative
people
obesity
via
its
central
effects
within
mesoaccumbens
pathway.
These
provide
evidence
for
how
can
act
neuromodulators
adapt
body's
state
agonists
work
clinics.
Neuroscience & Biobehavioral Reviews,
Journal Year:
2024,
Volume and Issue:
159, P. 105608 - 105608
Published: March 2, 2024
While
interoception
is
of
major
neuroscientific
interest,
its
precise
definition
and
delineation
from
exteroception
continue
to
be
debated.
Here,
we
propose
a
functional
distinction
between
based
on
computational
concepts
sensor-effector
loops.
Under
this
view,
the
classification
sensory
inputs
as
serving
or
depends
loop
they
feed
into,
for
control
either
bodily
(physiological
biochemical)
environmental
states.
We
explain
utility
perspective
by
examining
perception
skin
temperature,
one
most
challenging
cases
distinguishing
exteroception.
Specifically,
conceptualising
thermoception
inference
about
thermal
state
body
(including
skin),
which
directly
coupled
thermoregulatory
processes.
This
view
emphasises
coupling
regulation
(control)
defining
property
(inference)
connects
contemporary
theories
brain-body
interactions.
iScience,
Journal Year:
2024,
Volume and Issue:
27(4), P. 109586 - 109586
Published: March 27, 2024
Respiration
and
cardiac
activity
intricately
interact
through
complex
physiological
mechanisms.
The
heartbeat-evoked
potential
(HEP)
is
an
EEG
fluctuation
reflecting
the
cortical
processing
of
signals.
We
recently
found
higher
HEP
amplitude
during
exhalation
than
inhalation
a
task
involving
attention
to
sensations.
This
may
have
been
due
reduced
perception
heightened
attentional
To
investigate
relationships
between
HEP,
attention,
respiration,
we
introduced
experimental
setup
that
included
tasks
related
respiratory
interoceptive
exteroceptive
attention.
Results
revealed
increases
over
fronto-central
electrodes.
When
phases
were
taken
into
account,
primarily
driven
by
heartbeats
recorded
exhalation,
specifically
task,
while
had
minimal
impact.
These
findings
emphasize
role
respiration
in
could
implications
for
interventions
fine-tune
interoception.
European Journal of Neuroscience,
Journal Year:
2025,
Volume and Issue:
61(1)
Published: Jan. 1, 2025
Anxiety
is
one
of
the
most
common
and
debilitating
mental
health
disorders,
related
to
changes
in
interoception
(perception
bodily
states).
While
anxiety
more
prevalent
women
than
men,
gender
differences
interoception-anxiety
associations
are
often
overlooked.
Here,
we
examined
gender-specific
relationships
between
breathing
domain,
utilising
multicentre
data
pooled
from
four
study
sites
(N
=
175;
51%
women).
State
scores
were
quantified
via
Spielberger
State-Trait
Inventory,
breathing-related
interoceptive
dimensions
an
inspiratory
load
task
quantify
sensitivity,
decision
bias,
metacognitive
bias
(confidence
decisions),
insight
(congruency
performance
confidence).
Regression
analyses
revealed
a
significant
negative
relationship
state
(β
-0.28;
p
0.01)
-0.09;
95%
highest
density
interval
[HDI]
hierarchical
Bayesian
regression
[-0.18,
-0.004])
across
whole
sample,
while
did
not
relate
sensitivity
nor
bias.
no
mean
effects
relating
observed,
towards
was
driven
by
(women:
β
-0.18;
HDI
[-0.31,
-0.05];
men:
0.02;
[-0.12,
0.15])
with
interaction
effect
difference
-0.20;
[-0.37,
-0.01]),
which
hold
for
trait
depression
measures.
In
summary,
associated
decreased
all
participants,
only
but
men.
Therefore,
treatment
programmes
focusing
on
may
be
useful
patients,
might
represent
specific
target
anxiety.
Biological Psychology,
Journal Year:
2021,
Volume and Issue:
164, P. 108152 - 108152
Published: July 24, 2021
Neurocomputational
theories
have
hypothesized
that
Bayesian
inference
underlies
interoception,
which
has
become
a
topic
of
recent
experimental
work
in
heartbeat
perception.
To
extend
this
approach
beyond
cardiac
we
describe
the
application
computational
model
to
recently
developed
gastrointestinal
interoception
task
completed
by
40
healthy
individuals
undergoing
simultaneous
electroencephalogram
(EEG)
and
peripheral
physiological
recording.
We
first
present
results
support
validity
modelling
approach.
Second,
provide
test
of,
confirmatory
evidence
supporting,
neural
process
theory
associated
with
particular
framework
(active
inference)
predicts
specific
relationships
between
parameters
event-related
potentials
EEG.
also
offer
some
exploratory
suggesting
may
influence
regulation
states.
conclude
offers
promise
as
tool
for
studying
individual
differences
interoception.
