Emergence of Nanoplastic in the Environment and Possible Impact on Human Health

Environmental Science & Technology, Journal Year: 2019, Volume and Issue: 53(4), P. 1748 - 1765

Published: Jan. 10, 2019

On account of environmental concerns, the fate and adverse effects plastics have attracted considerable interest in past few years. Recent studies indicated potential for fragmentation plastic materials into nanoparticles, i.e., "nanoplastics," their possible accumulation environment. Nanoparticles can show markedly different chemical physical properties than bulk material form. Therefore risks hazards to environment need be considered addressed. However, effect nanoplastics (aquatic) has so far been little explored. In this review, we aim provide an overview literature on emerging topic, with emphasis reported impacts human health, including challenges involved detecting a biological We first discuss sources fates then describe entry routes these particles body, as well uptake mechanisms at cellular level. Since humans not yet extensively studied, focus demonstrating cell responses induced by polystyrene nanoparticles. particular, influence particle size surface chemistry are discussed, order understand recommendations future studies.

Language: Английский

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Microplastics in the marine environment: Current trends in environmental pollution and mechanisms of toxicological profile

Environmental Toxicology and Pharmacology, Journal Year: 2019, Volume and Issue: 68, P. 61 - 74

Published: March 7, 2019

Language: Английский

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Impacts of Plastic Pollution on Ecosystem Services, Sustainable Development Goals, and Need to Focus on Circular Economy and Policy Interventions

Sustainability, Journal Year: 2021, Volume and Issue: 13(17), P. 9963 - 9963

Published: Sept. 6, 2021

Plastic pollution is ubiquitous in terrestrial and aquatic ecosystems. waste exposed to the environment creates problems of significant concern for all life forms. production accumulation natural are occurring at an unprecedented rate due indiscriminate use, inadequate recycling, deposits landfills. In 2019, global plastic was 370 million tons, with only 9% it being recycled, 12% incinerated, remaining left or The leakage wastes into ecosystems rate. management a challenging problem researchers, policymakers, citizens, other stakeholders. Therefore, here, we summarize current understanding concerns plastics (microplastics nanoplastics) on overall goal this review provide background assessment adverse effects ecosystems; interlink sustainable development goals; address policy initiatives under transdisciplinary approaches through cycle assessment, circular economy, sustainability; identify knowledge gaps; recommendations. community involvement socio-economic inputs different countries presented discussed. ban policies public awareness likely major mitigation interventions. need circularity assess potential environmental impacts resources used throughout product’s span emphasized. Innovations needed reduce, reuse, recycle, recover find eco-friendly replacements plastics. Empowering educating communities citizens act collectively minimize use alternative options must be promoted enforced. that addressed utmost priority.

Language: Английский

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Microplastics in aquatic environments: Occurrence, accumulation, and biological effects

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 703, P. 134699 - 134699

Published: Nov. 5, 2019

Language: Английский

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Microplastics and associated contaminants in the aquatic environment: A review on their ecotoxicological effects, trophic transfer, and potential impacts to human health

Journal of Hazardous Materials, Journal Year: 2020, Volume and Issue: 405, P. 124187 - 124187

Published: Oct. 15, 2020

Language: Английский

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Recent advances in toxicological research of nanoplastics in the environment: A review

Environmental Pollution, Journal Year: 2019, Volume and Issue: 252, P. 511 - 521

Published: May 20, 2019

Language: Английский

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The plastic brain: neurotoxicity of micro- and nanoplastics

Particle and Fibre Toxicology, Journal Year: 2020, Volume and Issue: 17(1)

Published: June 8, 2020

Given the global abundance and environmental persistence, exposure of humans (aquatic) animals to micro- nanoplastics is unavoidable. Current evidence indicates that can be taken up by aquatic organism as well mammals. Upon uptake, reach brain, although there limited information regarding number particles reaches brain potential neurotoxicity these small plastic particles.Earlier studies indicated metal metal-oxide nanoparticles, such gold (Au) titanium dioxide (TiO2) also exert a range neurotoxic effects. similarities between chemically inert metal(oxide) nanoparticles particles, this review aims provide an overview reported effects in different species vitro. The combined data, fragmentary, indicate induce oxidative stress, potentially resulting cellular damage increased vulnerability develop neuronal disorders. Additionally, result inhibition acetylcholinesterase activity altered neurotransmitter levels, which both may contribute behavioral changes.Currently, systematic comparison particle types, shapes, sizes at concentrations durations lacking, but urgently needed further elucidate hazard risk nanoplastics.

Language: Английский

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Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature

Particle and Fibre Toxicology, Journal Year: 2020, Volume and Issue: 17(1)

Published: Nov. 12, 2020

Abstract Background Together with poor biodegradability and insufficient recycling, the massive production use of plastics have led to widespread environmental contamination by nano- microplastics. These particles accumulate across ecosystems - even in most remote habitats are transferred through food chains, leading inevitable human ingestion, that adds highest one due processes packaging. Objective The present review aimed at providing a comprehensive overview current knowledge regarding effects microplastics on intestinal homeostasis. Methods We conducted literature search focused vivo gut epithelium microbiota, as well immune response. Results Numerous animal studies shown exposure leads impairments oxidative inflammatory balance, disruption gut’s epithelial permeability. Other notable microplastic include dysbiosis (changes microbiota) cell toxicity. Moreover, contain additives, adsorb contaminants, may promote growth bacterial pathogens their surfaces: they potential carriers toxicants can potentially lead further adverse effects. Conclusion Despite scarcity reports directly relevant human, this brings together growing body evidence showing disturbs microbiota critical functions. Such development chronic disorders. Further investigation threat health is warranted.

Language: Английский

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Particulate plastics as a vector for toxic trace-element uptake by aquatic and terrestrial organisms and human health risk

Environment International, Journal Year: 2019, Volume and Issue: 131, P. 104937 - 104937

Published: July 5, 2019

Particulate plastics in the terrestrial and aquatic environments are small plastic fragments or beads (i.e., 5 mm down to nanometre range). They have been frequently referred as 'micro-plastics' 'nano-plastics'. Research has identified particulate a vector for toxic trace elements environment. The adsorption of by may be facilitated their high surface area functionalized surfaces (e.g., through attachment natural organic matter). Other factors, such environmental conditions pH water salinity), charge, element oxidation status, also influence onto plastics. Because size persistence, associated readily ingested accumulated many organisms. Thus, these can severe consequences, development metal toxicity, within Humans could become exposed food chain contamination airborne ingestion. This review provides an overview sources To this end, we describe made synthetic polymers, origin, characteristics with emphasis on how contaminate ecosystems. Future research needs strategies discussed help reduce risks potent transportation elements.

Language: Английский

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Micro- and nano-plastics activation of oxidative and inflammatory adverse outcome pathways

Redox Biology, Journal Year: 2020, Volume and Issue: 37, P. 101620 - 101620

Published: July 17, 2020

Microplastics (MPs) and nanoplastics (NPs) have attracted considerable attention in the recent years as potential threats to ecosystem public health. This review summarizes current knowledge of pathological events triggered by micro- nano-plastics (MP/NPs) with focus on oxidative damages at different levels biological complexity (molecular, cellular, tissue, organ, individual population). Based published information, we matched apical toxicity endpoints induced MP/NPs key event (KE) or adverse outcomes (AO) categorized them according Adverse Outcome Pathway (AOP) online knowledgebase. We used existing AOPs applied highlight formal mechanistic links between identified KEs AOs two possible scenarios: first from ecological, second health perspective. Ecological perspective AOP based literature analysis revealed that share formation reactive oxygen species their molecular initiating event, leading such growth inhibition behavior alteration through stress cascades inflammatory responses. Application data related showed its responding pathways, including responses, could play role events. However insufficient information prevented precise definitions this level. To overcome gap, further mammalian model epidemiological studies are necessary support development construction detailed focus.

Language: Английский

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