Aerobic Microbial Transformation of Fluorinated Liquid Crystal Monomer: New Pathways and Mechanism DOI

Xifen Zhu,

Yuanyuan Yu,

Weikun Meng

et al.

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 58(1), P. 510 - 521

Published: Dec. 15, 2023

Fluorinated liquid crystal monomers (FLCMs) have been suggested as emerging contaminants, raising global concern due to their frequent occurrence, potential toxic effects, and endurance capacity in the environment. However, environmental fate of FLCMs remains unknown. To fill this knowledge gap, we investigated aerobic microbial transformation mechanisms an important FLCM, 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3, 5-difluoro-4′-propylbiphenyl (DTMDPB), using enrichment culture termed BG1. Our findings revealed that 67.5 ± 2.1% initially added DTMDPB was transformed 10 days under optimal conditions. A total 14 products obtained a series reactions (e.g., reductive defluorination, ether bond cleavage, demethylation, oxidative hydroxylation aromatic ring opening, sulfonation, glucuronidation, O-methylation, thiolation) were identified. Consortium BG1 harbored essential genes could transform DTMDPB, such dehalogenation-related [e.g., glutathione S-transferase gene (GST), 2-haloacid dehalogenase (2-HAD), nrdB, nuoC, nuoD]; hydroxylating-related hcaC, ubiH, COQ7; opening-related ligB catE; methyltransferase ubiE ubiG. Two DTMDPB-degrading strains isolated, which are affiliated with genus Sphingopyxis Agromyces. This study provides novel insight into FLCMs. The implications for development bioremediation strategies aimed at addressing sites contaminated

Language: Английский

First Report on the Trophic Transfer and Priority List of Liquid Crystal Monomers in the Pearl River Estuary DOI

Yiye Jiang,

Yan‐Hong Zeng, Ling Long

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(36), P. 16131 - 16141

Published: Aug. 27, 2024

Liquid crystal monomers (LCMs) are emerging organic pollutants due to their potential persistence, toxicity, and bioaccumulation. This study first characterized the levels compositions of 19 LCMs in organisms Pearl River Estuary (PRE), estimated bioaccumulation trophic transfer potential, identified priority contaminants. were generally accumulated from sediment, LCM concentrations all ranged 32.35 1367 ng/g lipid weight. The main biphenyls analogues (BAs) (76.6%), followed by cyanobiphenyls (CBAs) (15.1%), least fluorinated (FBAs) (11.2%). most abundant BAs, FBAs, CBAs 1-(4-propylcyclohexyl)-4-vinylcyclohexane 1-ethoxy-2,3-difluoro-4-(4-(4-propylcyclohexyl) cyclohexyl) benzene (EDPBB, 10.1%), 4'-propoxy-4-biphenylcarbonitrile (5.1%), respectively. niche studies indicated that PRE food web was composed terrestrial-based diet marine chains. Most exhibited biodilution chains, except for EDPBB 4,4'-bis(4-propylcyclohexyl) biphenyl (BPCHB). hydrophobicity, position fluorine substitution LCMs, biological habits may be important factors affecting LCMs. BPCHB, 1-(prop-1-enyl)-4-(4-propylcyclohexyl) cyclohexane, as reports processes mechanisms biomonitoring PRE.

Language: Английский

Citations

1
Hepatotoxicity, Developmental toxicity, and Neurotoxicity Risks Associated with Co-exposure of Zebrafish to Fluoroquinolone Antibiotics and Tire Microplastics: An In Silico Study DOI
Jingya Wen, Yajing Liu, Bingjia Xiao

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136888 - 136888

Published: Dec. 15, 2024

Language: Английский

Citations

1
Probing the bioconcentration and metabolism disruption of bisphenol A and its analogues in adult female zebrafish from integrated AutoQSAR and metabolomics studies DOI
Pengyu Chen,

Yuxi Hu,

Geng Chen

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 905, P. 167011 - 167011

Published: Sept. 11, 2023

Language: Английский

Citations

3
Tissue-specific accumulation, depuration and histopathological effects of 3,6-dichlorocarbazole and 2,7-dibromocarbazole in adult zebrafish (Danio rerio) DOI

Mengyao Huang,

Cunchuang Hou,

Qiaoyun Zhang

et al.

Aquatic Toxicology, Journal Year: 2023, Volume and Issue: 266, P. 106803 - 106803

Published: Dec. 13, 2023

Language: Английский

Citations

3
Aerobic Microbial Transformation of Fluorinated Liquid Crystal Monomer: New Pathways and Mechanism DOI

Xifen Zhu,

Yuanyuan Yu,

Weikun Meng

et al.

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 58(1), P. 510 - 521

Published: Dec. 15, 2023

Fluorinated liquid crystal monomers (FLCMs) have been suggested as emerging contaminants, raising global concern due to their frequent occurrence, potential toxic effects, and endurance capacity in the environment. However, environmental fate of FLCMs remains unknown. To fill this knowledge gap, we investigated aerobic microbial transformation mechanisms an important FLCM, 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3, 5-difluoro-4′-propylbiphenyl (DTMDPB), using enrichment culture termed BG1. Our findings revealed that 67.5 ± 2.1% initially added DTMDPB was transformed 10 days under optimal conditions. A total 14 products obtained a series reactions (e.g., reductive defluorination, ether bond cleavage, demethylation, oxidative hydroxylation aromatic ring opening, sulfonation, glucuronidation, O-methylation, thiolation) were identified. Consortium BG1 harbored essential genes could transform DTMDPB, such dehalogenation-related [e.g., glutathione S-transferase gene (GST), 2-haloacid dehalogenase (2-HAD), nrdB, nuoC, nuoD]; hydroxylating-related hcaC, ubiH, COQ7; opening-related ligB catE; methyltransferase ubiE ubiG. Two DTMDPB-degrading strains isolated, which are affiliated with genus Sphingopyxis Agromyces. This study provides novel insight into FLCMs. The implications for development bioremediation strategies aimed at addressing sites contaminated

Language: Английский

Citations

3