Polymers,
Journal Year:
2023,
Volume and Issue:
15(21), P. 4199 - 4199
Published: Oct. 24, 2023
Molecularly
imprinted
polymers
(MIPs)
and
the
imprinting
technique
provide
polymeric
material
with
recognition
elements
similar
to
natural
antibodies.
The
template
of
choice
(i.e.,
antigen)
can
be
almost
any
type
smaller
or
larger
molecule,
protein,
even
tissue.
There
are
various
formats
MIPs
developed
for
different
medical
purposes,
such
as
targeting,
imaging,
assay
diagnostics,
biomarker
detection.
Biologically
applied
widely
used
currently
applications,
targeting
antigen
also
help
in
personalized
medicine.
synthetic
sites
tailor-made
function
analytics,
drug
delivery
systems.
This
review
will
cover
promising
clinical
applications
MIP
systems
recently
disease
diagnosis
treatment.
Chemosensors,
Journal Year:
2025,
Volume and Issue:
13(1), P. 11 - 11
Published: Jan. 8, 2025
Dual-
or
multi-template
molecularly
imprinted
polymers
have
been
an
attractive
research
field
for
many
years
as
they
allow
simultaneous
detection
of
more
than
one
target
with
high
selectivity
and
sensitivity
by
creating
template-specific
recognition
sites
multiple
targets
on
the
same
functional
monomer.
Dual/multi-template
molecular
imprinting
techniques
applied
to
identify,
extract,
detect
targets,
from
heavy
metal
ions
viruses,
different
methods,
such
high-performance
liquid
chromatography
(HPLC),
chromatography–mass
spectrometry
(LC-MS),
piezoelectric,
optical,
electrochemical
methods.
This
article
focuses
sensors
based
dual/multi-template
detecting
a
wide
range
Furthermore,
this
work
highlights
use
these
point-of-care
applications,
their
commercialization
integration
microfluidic
systems.
Chirality,
Journal Year:
2025,
Volume and Issue:
37(2)
Published: Feb. 1, 2025
ABSTRACT
An
enantioselective
voltammetric
sensor
(EVS)
comprising
a
paste
electrode
made
of
graphitized
thermal
Carboblack
C
(CBPE)
modified
with
Ni(II)
complex
based
on
(
S
)‐(2‐aminomethyl)pyrrolidine
and
3,5‐di‐
tert
‐butylsalicylaldehyde
was
developed
for
the
recognition
determination
naproxen
(Nap)
enantiomers.
The
proposed
characterized
by
scanning
electron
microscopy
(SEM),
energy‐dispersive
X‐ray
spectroscopy
(EDS‐SEM),
Fourier‐transform
infrared
(FT‐IR),
molecular
dynamics
quantum
chemical
simulations,
electrochemical
impedance
(EIS),
cyclic
voltammetry
(CV)
methods.
Using
differential
pulse
(DPV),
CBPE@(
)‐
Ni
found
to
have
good
selectivity
Nap
enantiomers
i
p1
/
R
=
1.43,
p2
1.27
first/second
peaks,
respectively).
demonstrates
highest
sensitivity
)‐Nap
(6.44
6.90
μA/mM
first
second
peaks).
linear
concentration
range
is
from
5.0
×
10
−5
1
−3
M
2.0
−4
)‐Nap,
respectively,
where
detection
limits
peaks
are
5.31
−7
4.96
7.40
6.79
)‐Nap.
suggested
successfully
tested
in
mixtures,
biological
fluids,
medicinal
drug
forms.
In
all
cases,
relative
standard
deviation
(RSD)
does
not
exceed
4.7%;
recovery
percentage
99.2%–101.3%.
The Analyst,
Journal Year:
2023,
Volume and Issue:
148(16), P. 3827 - 3834
Published: Jan. 1, 2023
A
novel
electrochemical
detection
method
based
on
a
nickel
ferrite@graphene
(NiFe2O4@Gr)
nanocomposite-containing
molecularly
imprinted
polymer
(MIP)
was
developed
for
the
sensitive
determination
of
butylated
hydroxyanisole
(BHA).
After
successful
completion
nanocomposite
production
under
hydrothermal
conditions,
NiFe2O4@Gr
and
sensor
were
characterized
using
microscopic,
spectroscopic
techniques.
According
to
characterization
results,
synthesis
core-shell
type
with
high
purity
efficiency
has
been
proved
be
successful.
modification
cleaned
glassy
carbon
electrode
(GCE)
nanocomposite,
analytical
applications
started
prepared
BHA
printed
GCE.
This
BPA
demonstrated
linearity
1.0
×
10-11-1.0
10-9
M
low
limit
(LOD,
3.0
10-12
M).
In
addition,
also
exhibited
excellent
selectivity,
stability,
reproducibility
reusability
performances
in
flour
analysis.
Critical Reviews in Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 20
Published: Jan. 22, 2024
Molecularly
imprinted
polymers
(MIPs)
have
become
more
prevalent
in
fabricating
sensor
applications,
particularly
medicine,
pharmaceuticals,
food
quality
monitoring,
and
the
environment.
The
ease
of
their
preparation,
adaptability
templates,
superior
affinity
specificity,
improved
stability,
possibility
for
downsizing
are
only
a
few
benefits
these
sensors.
Moreover,
from
medical
perspective,
monitoring
therapeutic
medications
determining
pharmaceutical
compounds
forms
biological
systems
is
very
important.
Additionally,
because
hazardous
to
environment,
effective,
quick,
affordable
determination
surrounding
environment
major
importance.
Concerning
variety
performance
criteria,
including
sensitivity,
low
detection
limits,
affordability,
MIP
sensors
outperform
other
published
technologies
analyzing
drugs.
have,
therefore,
been
widely
used
as
one
most
crucial
techniques
pharmaceuticals.
first
part
this
review
provides
detailed
explanation
many
polymerization
that
were
employed
create
high-performing
In
subsequent
section
review,
utilization
MIP-based
quantifying
drugs
specimens,
environmental
samples
covered
depth.
Finally,
critical
evaluation
potential
future
research
paths
clarifies
use
fields.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
921, P. 171169 - 171169
Published: Feb. 23, 2024
The
widespread
presence
of
pharmaceuticals
in
wastewater
effluents
after
treatment
stands
as
a
significant
challenge
faced
the
field
management
and
public
health.
Governments
scientific
community
have
worked
to
meet
this
urgent
need
for
effective
solutions.
Nevertheless,
development
detection
strategies
pharmaceutical
monitorization
capable
delivering
rapid,
on-site,
sensitive
responses
remains
an
ongoing
necessity.
In
work,
performance
previously
developed
molecularly
imprinted
polymer
(MIP)
based
electrochemical
sensor
detecting
atorvastatin
(ATV)
surface
waters
is
presented.
A
simple
preconcentration
method
followed
by
measurements
differential
pulse
voltammetry
(DPV)
0.1
M
phosphate
buffer
(pH
=
7),
was
implemented.
analytical
results
were
validated
with
those
obtained
on
set
16
water
samples
ultra-high
liquid
chromatography
coupled
tandem
mass
spectrometry
(UHPLC-MS/MS).
Additionally,
life
cycle
assessment
(LCA)
conducted
compare
environmental
impact
both
methodologies.
demonstrated
that
ATV
using
MIP-sensor
reliable
when
compared
found
UHPLC-MS/MS
presenting
robust
linear
correlation
coefficient
0.843.
LCA
show
novel
technique
has
lower
associated
impacts
than
UHPLC-MS/MS,
current
protocol
applied.
These
findings
highlight
potential
eco-friendly
tool
routine
analysis
point-of-care
monitoring
WWTP
samples.
