Photocatalytic multi-component synthesis of ester-containing quinoxalin-2(1H)-ones using water as the hydrogen donor DOI
Qiang Feng,

Jindong Hao,

Ya Wei Hu

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110582 - 110582

Published: Nov. 1, 2024

Language: Английский

Photochemical Trifluoromethylative Difunctionalization of Styrenes and Phenylacetylenes via a Catalytic EDA Platform DOI

Seshadri Reddy Nasireddy,

Ganesh Chandra Upreti,

Anand Singh

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(17)

Published: March 19, 2024

Abstract Herein we report a visible‐light‐induced trifluoromethylative difunctionalization of styrenes and phenylacetylenes using trifluoromethyl thianthrenium triflate (TT‐CF 3 + OTf − ). The transformation was enabled by the discovery photoactive catalytic EDA complex formed between carbazolyl dithiocarbamate TT‐CF . This three‐component reactivity platform establishes new paradigm for , significantly expanding its repertoire photochemically trifluoromethylation reactions.

Language: Английский

Citations

3
Photocatalytic synthesis of polyfluoroalkylated dihydropyrazoles and tetrahydropyridazines DOI

Ling-Li Liu,

Chengli Xiang,

Changduo Pan

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(77), P. 10764 - 10767

Published: Jan. 1, 2024

A photocatalytic trifluoromethylation/cyclization reaction of

Language: Английский

Citations

3
Electrochemical Quinuclidine-mediated Minisci-type Acylation of N-Heterocycles with Aldehydes DOI
Yongmei Li,

Liangbo Sun,

Sheng-Yang Huang

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(48), P. 6174 - 6177

Published: Jan. 1, 2024

The electro-generation of acyl radicals from both aromatic and aliphatic aldehydes is a synthetic challenge. We addressed this challenge by merging electro-oxidation quinuclidine-mediated HAT strategy.

Language: Английский

Citations

2
Unusual Regio‐ and Chemoselectivity in Oxidation of Pyrroles and Indoles Enabled by a Thianthrenium Salt Intermediate DOI Creative Commons
Jodie L. Hann, Catherine L. Lyall, Gabriele Kociok‐Köhn

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: unknown

Published: June 3, 2024

A dearomative oxidation of pyrroles to Δ

Language: Английский

Citations

2
The merger of electro-reduction and hydrogen bonding activation for a radical Smiles rearrangement DOI Creative Commons

Liyuan Lan,

Kun Xu, Cheng‐Chu Zeng

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(33), P. 13459 - 13465

Published: Jan. 1, 2024

An unprecedented radical smiles rearrangement of N -arylpropiolamides was realized by merging electro-reduction with hydrogen bonding activation. Enabled this dual activation strategy, the reduction potential shifted positively 218 mV.

Language: Английский

Citations

2
Visible-Light Photoredox-Catalyzed Difunctionalization of Alkynes with Quinoxalin-2(1H)-Ones, P4S10, and Alcohols DOI

Lianhui Song,

Chao Ma,

Jian Huang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(15), P. 10974 - 10986

Published: July 24, 2024

Visible-light photoredox-catalyzed method has been developed for the synthesis of quinoxalin-2(1H)-one-containing vinyl phosphorodithioates via direct difunctionalization alkynes with quinoxalin-2(1H)-ones, P4S10 and alcohols. This four-component reaction could be carried out under metal-free mild conditions, affording a number in moderate to good yields Z-isomers as major products. Photocatalytic radical mechanism is proposed based on results trapping fluorescence quenching experiments.

Language: Английский

Citations

2
Efficient synthesis of SCF3-containing 3-alkenylquinoxalinones via three-component radical cascade reaction DOI
Siyu Wang,

Chu L,

Wei Yang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(18), P. 3740 - 3745

Published: Jan. 1, 2024

An efficient and practical method for the synthesis of 3-alkenylquinoxalinones containing SCF

Language: Английский

Citations

1
Photocatalyst-free Light-Mediated Three-Component Alkoxy-, Hydroxy-, and Azidotrifluoromethylation of Alkenes DOI Creative Commons
Yingmin Ji, Aida Jaafar, Carolina Gimbert‐Suriñach

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(23), P. 6660 - 6665

Published: Jan. 1, 2024

A photocatalyst-free method enables efficient alkene difunctionalization in CF 3 -rich organic environments using accessible starting materials. This protocol is applicable for the synthesis of alkoxy, hydroxy, and azido derivatives.

Language: Английский

Citations

1
Photocatalytic Three‐Component α‐Trifluoroalkyl‐β‐heteroarylation of Unactivated Alkenes with Trifluoroacetates DOI
Yang He, Wenlin Wang, Yuanyuan An

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(27)

Published: May 23, 2024

Abstract We herein disclose a direct and practical photocatalytic three‐component α‐trifluoroalkyl‐β‐heteroarylation of various unactivated alkenes with trifluoroacetates quinoxalin‐2(1 H )‐ones. The reaction takes place via photoinduced LMCT process, allowing efficient synthesis variety 3‐fluoroalkylated )‐one derivatives in moderate to excellent yields under mild conditions.

Language: Английский

Citations

1
Electrochemical Trifluoromethylation of Alkynes: The Unique Role of DMSO as a Masking Auxiliary DOI Creative Commons
Ji‐Hoon Jang, Ho Seong Hwang,

Haeryeong Jeong

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

An electrochemical trifluoromethylation method for terminal alkynes has been developed, facilitating the synthesis of CF 3 -alkynes with DMSO as a masking auxiliary.

Language: Английский

Citations

1