ChemCatChem,
Journal Year:
2023,
Volume and Issue:
15(21)
Published: Aug. 16, 2023
Abstract
Visible
light‐induced
photocatalysis
has
been
widely
investigated,
which
offers
exciting
opportunities
to
build
new
catalytic
platforms
that
are
unattainable
under
ground
state
conditions.
Asymmetric
a
longstanding
challenge
due
the
high
reactivity
of
photogenerated
intermediates
leading
strong
background
reaction.
Carbonyl
group
is
an
important
fundamental
scaffold
in
organic
synthesis.
The
photocatalytic
asymmetric
transformations
carbonyl
compounds
for
synthesizing
enantioenriched
secondary
and
tertiary
alcohols
significant
value
but
remain
problematic.
Even
so,
series
intriguing
works
concerning
this
topic
have
reported
recent
year.
This
review
summarizes
advances
area,
mainly
dividing
into
single
synergetic
catalyst
systems,
mechanism
each
reaction
discussed.
Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(10), P. 4129 - 4136
Published: Jan. 1, 2023
A
green
and
efficient
procedure
for
photoinduced
generation
of
ketyl
radicals
with
no
use
any
external
photocatalyst
is
demonstrated,
enabling
a
series
important
C–C
coupling
reactions
in
synthetic
chemistry.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(18), P. 9994 - 10000
Published: May 1, 2023
Herein,
we
report
the
synthesis
of
a
bifunctional
photocatalyst,
Zr-OTf-EY,
through
sequential
modifications
metal
cluster
nodes
in
metal-organic
layer
(MOL).
With
eosin
Y
and
strong
Lewis
acids
on
nodes,
Zr-OTf-EY
catalyzes
cross-coupling
reactions
between
various
C-H
compounds
electron-deficient
alkenes
or
azodicarboxylate
to
afford
C-C
C-N
coupling
products,
with
turnover
numbers
up
1980.
In
Zr-OTf-EY-catalyzed
reactions,
acid
sites
bind
increase
their
local
concentrations
electron
deficiency
for
enhanced
radical
additions,
while
EY
is
stabilized
by
site
isolation
MOL
long-lived
catalyst
hydrogen
atom
transfer.
The
proximity
photostable
enhances
catalytic
efficiency
approximately
400
times
over
homogeneous
counterpart
reactions.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(21), P. 3847 - 3852
Published: May 22, 2023
A
new
method
for
conducting
a
reductive
alkylation/arylation
of
1,2-diketones
using
visible
light
and
unactivated
organic
halides
is
presented
in
this
article.
This
technique
does
not
require
photocatalyst
employs
Et3N,
tertiary
amine,
as
promoter.
amine
aids
generating
ketyl
radical
an
α-aminoalkyl
radical,
which
engages
C-X
bond
activation
via
halogen
atom
transfer
process
(XAT).
approach's
success
hinges
on
utilizing
Et3N
the
article's
mild
straightforward
protocol
allows
significantly
expanding
halide
substrates,
including
primary,
secondary,
aromatic
various
functional
groups.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(18), P. 10314 - 10321
Published: April 26, 2023
Samarium
diiodide
(SmI2)
mediated
reductive
coupling
reactions
are
powerful
methods
for
the
construction
of
carbon-carbon
bond
in
organic
synthesis.
Despite
extensive
development
recent
decades,
successful
examples
corresponding
asymmetric
remained
scarce,
probably
due
to
involvement
highly
reactive
radical
intermediates.
In
this
Article,
we
report
an
enantioselective
dearomatization
indoles
via
SmI2-mediated
intermolecular
with
ketones.
The
utilization
samarium
reductant
supported
by
chiral
tridentate
aminodiol
ligands
allows
facile
synthesis
indoline
molecules
bearing
two
contiguous
stereogenic
centers
high
yields
(up
99%)
and
stereoselectivity
99:1
er
>20:1
dr).
Combined
experimental
computational
investigations
suggested
that
parallel
single-electron
transfer
each
substrate
from
radical-radical
recombination
manner,
which
is
a
unique
mechanistic
scenario
reactions.
ChemCatChem,
Journal Year:
2023,
Volume and Issue:
15(21)
Published: Aug. 16, 2023
Abstract
Visible
light‐induced
photocatalysis
has
been
widely
investigated,
which
offers
exciting
opportunities
to
build
new
catalytic
platforms
that
are
unattainable
under
ground
state
conditions.
Asymmetric
a
longstanding
challenge
due
the
high
reactivity
of
photogenerated
intermediates
leading
strong
background
reaction.
Carbonyl
group
is
an
important
fundamental
scaffold
in
organic
synthesis.
The
photocatalytic
asymmetric
transformations
carbonyl
compounds
for
synthesizing
enantioenriched
secondary
and
tertiary
alcohols
significant
value
but
remain
problematic.
Even
so,
series
intriguing
works
concerning
this
topic
have
reported
recent
year.
This
review
summarizes
advances
area,
mainly
dividing
into
single
synergetic
catalyst
systems,
mechanism
each
reaction
discussed.
