Chemistry - A European Journal,
Journal Year:
2023,
Volume and Issue:
29(32)
Published: March 30, 2023
Adrenaline,
also
known
as
epinephrine,
is
a
neurotransmitter/hormone
that
an
important
target
in
diagnostics.
Development
of
effective
method
for
detecting
it
the
presence
other
neurotransmitters
challenging
task.
The
electrochemical
and
fluorescent
techniques
commonly
used
have
low
selectivity
distinguishing
among
catecholamines.
Herein,
small-molecule
organic
probe
with
activated
furfural
moiety
reported
to
exploit
nucleophilicity
epinephrine
generate
bright-colored
donor-acceptor
Stenhouse
adduct.
Among
nine
common
or
their
analogues,
only
was
found
unique
colour
change
discernible
naked
eye,
whereas
ones
remain
unaffected.
Under
various
in-field
detection
conditions,
including
solution,
droplet,
paper
strip-based
detection,
were
noticeable.
limit
1.37
nM
quantitation
4.37
achieved
simple
UV/Vis
methods
addition
sub-ppm
level
sensing
under
visual
conditions
eyes.
could
be
practical
colorimetric
measurements
point-of-care
tool
without
any
complex
expensive
machinery,
making
this
approach
accessible
all.
In
addition,
using
smartphone,
determination
concentrations
possible
by
machine-learning
techniques.
Environmental Science Nano,
Journal Year:
2024,
Volume and Issue:
11(3), P. 766 - 796
Published: Jan. 1, 2024
Here
we
made
a
critical
review
on
nanozyme-involved
detection
and
degradation
of
environmental
pollutants,
the
research
progress
achieved
in
last
five
years
was
emphatically
concluded.
Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
95(5), P. 2865 - 2873
Published: Jan. 24, 2023
Nanozymes
can
imitate
the
catalytic
properties
of
natural
enzymes
while
overcoming
limitations
such
as
high
cost,
poor
robustness,
and
difficulty
in
recycling.
However,
rational
design
facile
preparation
nanozymes
are
still
demand.
Inspired
by
chemical
structure
laccase,
we
report
an
amorphous
metal-organic
coordination
nanocomposite
named
CuNAD,
which
is
composed
copper
ions
nicotinamide
adenine
dinucleotide
(NAD+)
via
a
simple
coordinating
coassembly
process.
As
single-site
nanozyme,
CuNAD
exhibits
excellent
robustness
under
extreme
conditions,
significantly
stronger
activity
for
phenolic
compounds,
4.02-fold
higher
sensitivity
epinephrine
detection
than
laccase.
Furthermore,
breaking
through
functional
constraints
also
able
to
activate
H2O2
at
neutral
pH,
benefiting
one-step
chromogenic
platform
cholesterol.
This
approach
demonstrates
potential
develop
biomimicking
may
boost
more
insights
into
structure-function
relationship
nanozymes.
