Designing osteogenic interfaces on 3D-Printed thermoplastic bone scaffolds DOI
Ankita Negi,

Kajal Goswami,

Himanshi Diwan

et al.

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102635 - 102635

Published: March 13, 2025

Language: Английский

Chitosan-based scaffolds as drug delivery systems in bone tissue engineering DOI

R Bharathi,

S. Shree Ganesh,

Ganesh Harini

et al.

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 222, P. 132 - 153

Published: Sept. 13, 2022

Language: Английский

Citations

78

DLC coatings in biomedical applications – Review on current advantages, existing challenges, and future directions DOI
Raj Shah, Nikhil Pai,

Rahul Khandekar

et al.

Surface and Coatings Technology, Journal Year: 2024, Volume and Issue: 487, P. 131006 - 131006

Published: June 13, 2024

Language: Английский

Citations

19

Recent Advancements in the Surface Modification of Additively Manufactured Metallic Bone Implants DOI Creative Commons

Jianhui Li,

Haitao Fan,

Hui Qiang Li

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 200195 - 200195

Published: Jan. 1, 2025

Language: Английский

Citations

2

Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications DOI Creative Commons
Francesca Accioni, Juan Vázquez, Manuel Merinero

et al.

Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(2), P. 455 - 455

Published: Feb. 21, 2022

An increase in the world population and its life expectancy, as well ongoing concern about our physical appearance, have elevated relevance of dental implantology recent decades. Engineering strategies to improve survival rate implants been widely investigated, focusing on implant material composition, geometry (usually guided reduce stiffness), interface surrounding tissues. Although efforts develop different surface modifications are being applied commercial prostheses today, inclusion coatings has gained special interest, they can be tailored efficiently enhance osseointegration, bacterial-related infection, minimizing peri-implantitis appearance associated risks. The use biomaterials replace teeth highlighted need for development reliable analytical methods assess therapeutic benefits implants. This literature review considers state-of-the-art modification or coating methodologies increasing restoration.

Language: Английский

Citations

63

Silver─Gallium Nano‐Amalgamated Particles as a Novel, Biocompatible Solution for Antibacterial Coatings DOI Creative Commons
Tien Thanh Nguyen, Pengfei Zhang,

Jingwei Bi

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(31)

Published: Nov. 5, 2023

Abstract Bacterial infections account for countless deaths globally. Antibiotics are the primary countermeasure; however, alarming spread of antibiotic‐resistant strains necessitates alternative solutions. Silver and silver compounds have emerged as promising antibacterial agents. However, issues related to cytotoxicity genotoxicity remain concern. To overcome these challenges, this proposes an easy‐to‐control straightforward method synthesize novel Silver─gallium (Ag─Ga) nano‐amalgamated particles. Gallium liquid metal (GaLM) is used facilitate galvanic deposition nanocrystals (Ag) on oxide layer. The GaLM not only serves a carrier through replacement process, but also provides controlled‐release mechanism silver, in way improving biocompatibility, reducing inflammation, stimulating bone growth. Notably, Ag─Ga suspensions can be conveniently deposited by spray‐coating range devices material surfaces, effectively eliminating pathogenic bacteria with efficacy comparable that ions. In vivo studies rat models affirm capabilities, especially against methicillin‐resistant Staphylococcus aureus Escherichia coli , when placed implants such titanium rods magnesium discs. Furthermore, promotes matrix formation collagen growth without eliciting inflammatory response, indicating major promise coatings wide variety biomedical materials.

Language: Английский

Citations

41

Decoding bone-inspired and cell-instructive cues of scaffolds for bone tissue engineering DOI Creative Commons
Zahid Hussain, Shah Mehmood, Xingzhu Liu

et al.

Engineered Regeneration, Journal Year: 2023, Volume and Issue: 5(1), P. 21 - 44

Published: Oct. 27, 2023

Bone fractures are common occurrence in clinical settings, creating a high demand for effective repair material. Unfortunately, limited graft availability, donor site morbidities, unpredictable outcomes, immunologic reactions, infection risks, and geometrical mismatching concerns hampered tissue use underscored the need scaffolds more bone reconstructions due to their tunable properties. Significant progress has been carried out past decade fields of nanoceramics synthesis, bioconjugate chemistry, composite material processing. This review outlines hierarchical structures biology tissue, materialistic components (bioceramics, polymers, bioactive drugs), featured scaffolding strategies (nanofibers, hydrogels, aerogels, bioprinting, fiber-reinforced composite), emphasis that physiochemical characteristics should be used as an inspiration scaffold design. discussed how differences materiobiological aspects scaffolds, such polymer/bioceramic nanocomposite, mineralized matrix-rich 3D microenvironmental cues, pore space mechanical usage physical stimulation (magnetic, electroactive, photoactivated cues), surface cues (wettability, roughness, textured, charge), biointerface (cell–biomaterial interactions, cell-selective homing, cell regulatory strategies) modulate cellular biological response engineering. study further challenges benefits integrating

Language: Английский

Citations

30

Advances and significances of titaniumin dental implant applications DOI Creative Commons
Nayem Hossain, Mohammad Aminul Islam, Md Mir Shakib Ahmed

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 7, P. 101394 - 101394

Published: Jan. 1, 2024

Titanium has an extensive record of serving as excellent option for the material used in implant construction. It been demonstrated that certain Ti alloys are superior to other types every respect. Better osseointegration is a critical component implants, and titanium's biocompatibility, corrosion tribology, microstructure, cell adhesion mechanism have subject intensive study several years. Significant strides made dental research thanks company's production process, analysis material's properties, creation new innovative alloys. More studies should be done at dentistry site on human bone determine its compatibility with metals In this article, we will discuss latest advancements regarding resistance, mechanical stability, surface chemistry, electromechanical behavior titanium implants. addition that, also recent developments production, such additive manufacturing technology, well characterization techniques, microstructure characterization, testing, biocompatibility tests, clinical use

Language: Английский

Citations

16

RGO@β-CaSiO3:Sm3+ nanocomposites for super capacitors, biosensor and w-LEDs applications DOI
Nandini Robin Nadar,

J. Deepak,

S.C. Sharma

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

9

Nanoparticles of Natural Product-derived Medicines: Beyond the Pandemic DOI Creative Commons
Yedi Herdiana

Heliyon, Journal Year: 2025, Volume and Issue: 11(4), P. e42739 - e42739

Published: Feb. 1, 2025

This review explores the synergistic potential of natural products and nanotechnology for viral infections, highlighting key antiviral, immunomodulatory, antioxidant properties to combat pandemics caused by highly infectious viruses. These often result in severe public health crises, particularly affecting vulnerable populations due respiratory complications increased mortality rates. A cytokine storm is initiated when an overload pro-inflammatory cytokines chemokines released, leading a systemic inflammatory response. Viral mutations limited availability effective drugs, vaccines, therapies contribute continuous transmission virus. The coronavirus disease-19 (COVID-19) pandemic has sparked renewed interest product-derived antivirals. efficacy traditional medicines against infections examined. Their anti-inflammatory, are highlighted. discusses how enhances herbal combating infections.

Language: Английский

Citations

1

Soft and Hard Tissue Integration around Percutaneous Bone-Anchored Titanium Prostheses: Toward Achieving Holistic Biointegration DOI

Sangeeta Shrivas,

Harshita Samaur,

Vinod Yadav

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: 10(4), P. 1966 - 1987

Published: March 26, 2024

A holistic biointegration of percutaneous bone-anchored metallic prostheses with both hard and soft tissues dictates their longevity in the human body. While titanium (Ti) has nearly solved osseointegration, tissue integration is a perennial problem. Unlike firm sealing biological structures (fingernails teeth), foreign body response skin to leads inflammation, epidermal downgrowth inferior peri-implant sealing. This review discusses various implant surface treatments/texturing coatings for integration, against bacterial attachment. microroughness by SLA (sandblasting large grit acid etched) porous calcium phosphate (CaP) improve Ti smooth textured titania nanopores, nanotubes, microgrooves, biomolecular encourage However, compared natural teeth can lead peri-implantitis. Toward this end, application smart multifunctional bioadhesives strong adhesion tissues, mechanical resilience, durability, antibacterial, immunomodulatory properties attachment proposed.

Language: Английский

Citations

7