Near-Infrared Fluorescent Turn-On Probe for Selective Detection of Hypochlorite in Aqueous Medium and Live Cell Imaging DOI
Anwesha Maiti, Saikat Kumar Manna, Satyajit Halder

et al.

Chemical Research in Toxicology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Hypochlorite, as an important reactive oxygen species (ROS), plays a vital role in many physiological and pathological processes, but excess concentration of hypochlorite (ClO

Language: Английский

A naphthalimido-based fluorescent probe for HOCl sensing with excellent lysosome-targeted performance DOI
Nuo Li,

Qiuyan Tan,

Qing Wang

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141393 - 141393

Published: Jan. 1, 2025

Language: Английский

Citations

2
A “turn-on” fluorescence probe based on a novel hypochlorous acid-induced cyclization response mechanism, and its applications in real water samples and bioimaging in vitro and in vivo DOI
Qian Han,

Zhuye Shang,

Tingwei Zhang

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1318, P. 139361 - 139361

Published: July 22, 2024

Language: Английский

Citations

6
Fast and easy detection of hypochlorite by a smartphone-based fluorescent turn-on probe: Applications to water samples, zebrafish and plant imaging DOI
Sooseong Lee, Jae Jun Lee, Sumin Jung

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 317, P. 124418 - 124418

Published: May 7, 2024

Language: Английский

Citations

5
Fluorescent probe-mediated labeling and real-time tracking of lipid droplet dynamics in foam cells formation DOI
Jiandong Liu,

Xingfang Wang,

Jingyi Yu

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 414, P. 135942 - 135942

Published: May 8, 2024

Language: Английский

Citations

5
A FRET/TICT based multifunctional fluorescent probe for the monitoring of SO2 derivatives and viscosity in living cells and real samples DOI
Jianfeng Wang, Xiaoling Cui,

Shenghui Lun

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 325, P. 125074 - 125074

Published: Aug. 31, 2024

Language: Английский

Citations

5
Unraveling Ferroptosis Mechanisms: Tracking Cellular Viscosity with Small Molecular Fluorescent Probes DOI
Niharika Pareek,

Sana Mendiratta,

Nripankar Kalita

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: 19(8)

Published: March 2, 2024

Ferroptosis is a recently identified form of regulated cell death characterized by iron accumulation and lipid peroxidation. Numerous functions for ferroptosis have been in physiological as well pathological processes, most notably the treatment cancer. The intricate balance redox homeostasis profoundly altered during ferroptosis, leading to alteration cellular microenvironment. One such microenvironment viscosity among others pH, polarity, temperature. Therefore, understanding dynamics associated levels within organelles crucial. To date, there are very few reviews that detects assessing reactive species. In this review, we summarized organelle's specific fluorescent probes microviscosity ferroptosis. Also, offer readers an insight their design strategy, photophysics bioimaging concluding with future perspective challenges related field.

Language: Английский

Citations

4
Molecular probes for tracking lipid droplet membrane dynamics DOI Creative Commons

Lingxiu Kong,

Qingshun Bai,

Cuicui Li

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 31, 2024

Lipid droplets (LDs) feature a unique monolayer lipid membrane that has not been extensively studied due to the lack of suitable molecular probes are able distinguish this from LD core. In work, we present three-pronged probe design strategy combines lipophilicity-based organelle targeting with microenvironment-dependent activation and an labeling pro-probe called LDM. Upon by HClO/ClO− microenvironment surrounds LDs, LDM releases LDM-OH binds proteins thus enabling visualization ring-like membrane. By utilizing LDM, identify dynamic mechanism contacts their protein accumulation parameters. Taken together, represents first for imaging membranes in live cells best our knowledge, attractive tool further investigations into specific regulatory mechanisms LD-related metabolism diseases drug screening. play essential roles many biological processes, but LDs probes. Here, authors report labelling which, upon undergoes color change proteins.

Language: Английский

Citations

4
Polarity, pH and HClO triple-response fluorescent probe and its application in inflammation models DOI

Ying Liu,

Weiling Yan,

Jingyu Li

et al.

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 126953 - 126953

Published: Jan. 1, 2025

Language: Английский

Citations

0
Unique isophorone-based NIR fluorescent probe with a high fluorescence quantum yield and larger stokes shift for Al3+ and Zn2+ level simultaneous monitoring in biological system DOI

Ya-Tong Liu,

Qianqian Zhang,

Si-Yi Yao

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 335, P. 126001 - 126001

Published: March 6, 2025

Language: Английский

Citations

0
Dual-Color Visualization of Hepatic Fibrosis and Multidimensional Assessment of Therapeutic Drugs by a Multifunctional Single-Molecular Fluorescent Probe DOI

Jiale Ou,

Min Fang, Man Chen

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

There is a high relevance between changes in ClO- levels/mitochondrial morphology and the development of hepatic fibrosis; however, efficient tools that are capable real-time monitoring both them exploring their interrelations extremely rare. Herein, we developed multifunctional fluorescent probe based on "three-in-one" strategy, named Mito-XS, which firmly anchored mitochondria, allowing for ratiometric detection accurate analysis mitochondrial morphology. Probe Mito-XS can sensitively capture levels mitochondria successfully achieve simultaneous during oxidative stress. Utilizing evaluations three therapeutic drugs (silymarin, methyl ferulic acid, puerarin) protecting cells from CCl4-induced damage were visualized by assessing capabilities inhibiting maintaining Furthermore, dual-color imaging fibrosis mice models revealed exacerbation fibrosis, effect puerarin be tracked fluctuation levels. Therefore, an effective tool to monitor at same time has potential work as evaluation screen treatment.

Language: Английский

Citations

0