Functionalized Quantum Dots as Antimicrobial Agents DOI
Namrata Singh,

Rajeshree Shinde,

Bhanushree Gupta

et al.

Published: Jan. 1, 2024

It can be challenging to treat disorders linked infectious immunodeficiency when bacteria develop antibiotic resistance. Nanomaterials with dedicated antibacterial properties have played a promising role in treating bacterial infections. In comparison traditional antibiotics, quantum dots (QDs) exhibit not only exceptional structural stability but also photoluminescence characteristics for imaging and photodynamic therapy. Excessive use of QDs biomedical research is related their low toxicity. To boost antimicrobial efficacy, normally are functionalized, this chapter will summarize various QD functionalization effective against agents. Emphasis given carbon as they proved possess good bacteriostatic bactericidal properties. Graphene (GQDs) stand out among other graphene derivatives because the amazing optical, electrical, electrochemical therefore provide greater potential application than nanoparticles, challenges under physiological conditions often ignored. Herein, we discuss associated parallel activity. A variety functionalized mechanism discussed.

Language: Английский

Comprehensive Overview of Controlled Fabrication of Multifunctional Fluorescent Carbon Quantum Dots and Exploring Applications DOI
Lijuan Yang,

Yibo An,

Dazhuang Xu

et al.

Small, Journal Year: 2024, Volume and Issue: 20(29)

Published: Feb. 11, 2024

Abstract In recent years, carbon dots (CDs) have garnered increasing attention due to their simple preparation methods, versatile performances, and wide‐ranging applications. CDs can manifest various optical, physical, chemical properties including quantum yield (QY), emission wavelength (Em), solid‐state fluorescence (SSF), room‐temperature phosphorescence (RTP), material‐specific responsivity, pH sensitivity, anti‐oxidation oxidation, biocompatibility. These be effectively regulated through precise control of the CD process, rendering them suitable for diverse However, lack consideration given each feature during process poses a challenge in obtaining requisite features This paper is analyze existing research present novel concepts ideas creating with different distinct The synthesis methods are discussed first section, followed by comprehensive overview important modification strategy. Subsequently, application reviewed. Finally, outlines current challenges controlling applications, discusses potential solutions, offers suggestions future research.

Language: Английский

Citations

18

Carbon-in-carbon: Hybrid carbonized nanomaterials with multifunctional activities for the treatment of endophthalmitis DOI

Hong‐Jyuan Jian,

Yi‐Ru Chiou,

Anisha Anand

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 491, P. 151997 - 151997

Published: May 7, 2024

Language: Английский

Citations

11

Biofilm Inhibition on Medical Devices and Implants Using Carbon Dots: An Updated Review DOI
Eepsita Priyadarshini, Rohit Kumar,

Kalpana Balakrishnan

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(5), P. 2604 - 2619

Published: April 16, 2024

Biofilms are an intricate community of microbes that colonize solid surfaces, communicating via a quorum-sensing mechanism. These microbial aggregates secrete exopolysaccharides facilitating adhesion and conferring resistance to drugs antimicrobial agents. The escalating global concern over biofilm-related infections on medical devices underscores the severe threat human health. Carbon dots (CDs) have emerged as promising substrate combat disrupt biofilm matrices. Their numerous advantages such facile surface functionalization specific properties, position them innovative anti-biofilm Due their minuscule size, CDs can penetrate cells, inhibiting growth cytoplasmic leakage, reactive oxygen species (ROS) generation, genetic material fragmentation. Research has demonstrated efficacy in biofilms formed by key pathogenic bacteria

Language: Английский

Citations

8

Multifunctional Self-Healing Carbon Dot–Gelatin Bioadhesive: Improved Tissue Adhesion with Simultaneous Drug Delivery, Optical Tracking, and Photoactivated Sterilization DOI
Maansi Aggarwal, Harekrishna Panigrahi, Dinesh K. Kotnees

et al.

Biomacromolecules, Journal Year: 2024, Volume and Issue: 25(5), P. 3178 - 3189

Published: April 17, 2024

Bioadhesives with all-inclusive properties for simultaneous strong and robust adhesion, cohesion, tracking, drug delivery, self-sterilization, nontoxicity are still farfetched. Herein, a carbon dot (CD) is made to infuse each of the above-desired aspects gelatin, an inexpensive edible protein. The CD derived through controlled hydrothermal pyrolysis dopamine terephthaldehyde retained –NH2, –OH, –COOH, and, most importantly, –CHO functionality on surface efficient skin adhesion cross-linking. Facile fabrication CD–gelatin bioadhesive covalent conjugation –NH2 gelatin Schiff base formation was accomplished. This imparts remarkable self-healing attributes as well excellent cohesion evident from physicomechanical analysis in porcine model. Improved porosity allows loading hemin model whose disembarkment tracked intrinsic photoluminescence. In significant achievement, antibiotic-free self-sterilization demonstrated visible light (white LED, 23 W)-irradiated photosensitization produce reactive oxygen species annihilation both Gram-positive Gram-negative bacteria exceptional efficacy (99.9%). Thus, comprehensive superficial localized wound management reported promising step transformation domain nanotization futuristic clinical translations.

Language: Английский

Citations

8

Unlocking the Potential and Versatility of Quantum Dots: from Biomedical to Environmental Applications and Smart Micro/Nanorobots DOI Creative Commons
Martina Ussia, V. Privitera, Silvia Scalese

et al.

Advanced Materials Interfaces, Journal Year: 2024, Volume and Issue: 11(17)

Published: May 15, 2024

Abstract Quantum dots (QDs) are recognized as the most promising functional nanotechnology, for which its discoverers awarded Nobel Prize in 2023. Their remarkable tunability of optoelectronic properties has attracted significant interest from both researchers and industries, placing QDs at forefront developing cutting‐edge technologies. This comprehensive review aims to explore exciting results terms fundamental science, present forthcoming applications. Beyond their contributions biomedicine, energy, environmental quantum sensing, information processing, have brought important due integration into micro/nanorobotic systems, self‐propelled materials representing state art research micro nanoscale. These hybrid systems demonstrated noteworthy outcomes, unlocking novel possibilities accurately reviewed this article. In conclusion, addresses current challenges, offering insights facilitate further research, stimulate new developments, enhance comprehension full potential QDs.

Language: Английский

Citations

7

Novel, Speedy, and Eco-Friendly Carboxymethyl Cellulose-Nitrogen Doped Carbon Dots Biosensors with DFT Calculations, Molecular Docking, and Experimental Validation DOI Creative Commons

Hebat‐Allah S. Tohamy

Gels, Journal Year: 2024, Volume and Issue: 10(11), P. 686 - 686

Published: Oct. 24, 2024

Carboxymethyl cellulose (CMC) was prepared from sugarcane bagasse (SB) in minutes using a novel microwave method. Additionally, nitrogen-doped carbon dots (N-CDs) were synthesized SB the same technique. These materials crosslinked with CaCl

Language: Английский

Citations

7

An Injectable Chitosan-based Hydrogel Incorporating Carbon Dots with Dual Enzyme-Mimic Activities for Synergistically Treatment of Bacteria Infected Wounds DOI
Han Zhang,

Lu Gao,

Xiaodan Qi

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 241, P. 114006 - 114006

Published: May 29, 2024

Language: Английский

Citations

5

Antibacterial potentials of carbon dots immobilized on chitosan and glass surfaces DOI

Yanar Najmalden Ghaibullah Ghaibullah,

Egemen Foto, Naciye Özdemir

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 257, P. 128586 - 128586

Published: Dec. 4, 2023

Language: Английский

Citations

13

A Facile and Green Approach for the Preparation of Silver Nanoparticles on Graphene Oxide with Favorable Antibacterial Activity DOI Creative Commons
Talía Tene, Stefano Bellucci, Joseth Pachacama

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(17), P. 1455 - 1455

Published: Sept. 7, 2024

Herein, we introduce a simple precipitation method for preparing graphene oxide–silver nanoparticle (GO/AgNP) composites, utilizing Calendula officinalis (C. officinalis) seed extract as both reducing and stabilizing agent. Our research combines the sustainable preparation of oxide (GO) with green synthesis silver nanoparticles (AgNPs), aiming to explore potential obtained composite novel antibacterial material. To establish benchmark, was also performed using sodium citrate, conventional The resultant GO/AgNP composites were characterized through several analytical techniques, including scanning electron microscopy (SEM), transmission (TEM), atomic force (AFM), energy dispersive X-ray spectroscopy (EDS), Raman spectroscopy, diffraction (XRD), infrared (IR) ultraviolet–visible (UV-vis) confirming successful functionalization GO AgNPs. effectiveness systematically assessed against Escherichia coli (E. coli) Staphylococcus aureus (S. aureus), concentrations spanning from 0 250 µg/mL, mostly disk diffusion colony-forming unit (CFU) count assays. AgNPs by size range 15–50 nm. Notably, prepared C. demonstrated superior activity at all tested concentrations, outperforming pure citrate. most pronounced effect observed concentration 32.0 µg/mL. Therefore, this innovative approach may offer valuable contribution development new therapeutic agents combat bacterial infections, suggesting further exploration into coatings or drug development.

Language: Английский

Citations

4

One-step hydrothermal synthesis of F,N,S-doped photoluminescent carbon dots with yellowish-orange emission for sensitive Cu2+ ion detection: Environmental and biomedical applications DOI
Sonaimuthu Mohandoss,

Kuppu Sakthi Velu,

Rizwan Wahab

et al.

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 459, P. 116037 - 116037

Published: Sept. 16, 2024

Language: Английский

Citations

4