Adaptability of Polish Red cows to extensive conditions DOI Creative Commons
Witold Chabuz, Paweł Żółkiewski, Wioletta Sawicka-Zugaj

et al.

BMC Veterinary Research, Journal Year: 2025, Volume and Issue: 21(1)

Published: May 9, 2025

This study assessed the adaptive capacity of Polish Red cattle, one oldest indigenous dual-purpose breeds in Europe, to extensive environmental conditions north-eastern Poland. Twenty-two pregnant cows (average lactation number: 4.6) were divided into two groups: maintained a highly 'bale grazing' system (EXT), and other under traditional housing for suckler (TRAD). The experiment was conducted from onset winter through end subsequent pasture season. Parameters included changes body weight condition score (BCS), calf growth performance, milk yield, haematological biochemical blood indices. Statistical analysis performed using independent-samples t-tests Mann-Whitney U test (p ≤ 0.05, p 0.01). Despite challenging EXT group, including no shelter exposure variable climatic factors, health comparable TRAD group. While group calves showed superior (29 kg higher weight, 0.01), exhibited remarkable resilience by supporting survival with minimal loss 4.4 loss, less than 1% initial weight). Blood parameters remained within physiological ranges both groups, confirming breed's adaptability. These findings provide first experimental evidence adaptability cattle farming systems, highlighting their potential as valuable genetic resource sustainable livestock production increasing variability. conclusion has significant implications conservation biodiversity development climate-resilient breeding Europe.

Language: Английский

Dissecting genomes of multiple yak populations: unveiling ancestry and high-altitude adaptation through whole-genome resequencing analysis DOI Creative Commons
Sheikh Firdous Ahmad,

Munish Gangwar,

Amit Kumar

et al.

BMC Genomics, Journal Year: 2025, Volume and Issue: 26(1)

Published: March 3, 2025

The present study was undertaken to elucidate the population structure and differentiation of Indian yak from Chinese wild cohorts on genome-wide scale by identifying selection sweeps genomic basis their adaptation across different comparisons while analyzing whole genome sequencing (WGS) data using latest bioinformatics tools. included 105 individuals three distinct populations i.e., (n = 29); 61) 15), hypothesized be related along evolutionary timescale. Efficient variant calling quality control in GATK PLINK programs resulted around 1 million (1,002,970) high-quality (LD-independent) SNPs with an average genotyping rate 96.55%. PCA, ADMIXTURE TREEMIX analysis revealed stratification groups into clusters. empirical distribution pattern minor allele frequency (MAF) also elucidated for revealing unique five bins. signature candidate genes that are important against harsh environmental conditions habitats. Under iHS analysis, several were identified under pressure including ABCA12, EXOC1, JUNB, KLF1, PRDX2, NANOS3, RFX1, RFX2, CACNG7. On other hand, like NR2F2, OSBPL10, CIDEC, WFIKKN2, ADCY, THSD7A, ADGRB3, TRPC1, VASH2, ABHD5 part selective these comparisons. A total 53 found common between intra- inter-population yak. Notably, harbouring significant traits lipidogenesis, energy metabolism, thermogenesis, hair follicle formation, oxidation–reduction reactions, hypoxia reproduction. These may evaluated as livestock further research application era climate change.

Language: Английский

Citations

0
Effects of Heat Shock Protein 70 Gene Polymorphism on Heat Resistance in Beef and Dairy Calves Based on Proliferation and Heat Shock Protein 70 Gene Expression in Peripheral Blood Mononuclear Cells and Hair Follicles DOI Creative Commons

Won Seob Kim,

Yong-Ho Jo, Jalil Ghassemi Nejad

et al.

Animals, Journal Year: 2025, Volume and Issue: 15(4), P. 475 - 475

Published: Feb. 7, 2025

The study objectives were to investigate the heat resistance using peripheral blood mononuclear cells (PBMCs) and hair follicles in beef dairy calves based on shock protein (HSP) 70 genetic polymorphisms. follicle samples from sixty (6 months old; 30 Korean native Holstein calves) collected for DNA extraction. HSP70 single nucleotide polymorphism (SNP) was genotyped a 5′-exonuclease activity (TaqMan) assay. In Study 1, PBMCs isolated 20 categorized by their genotypes during thermoneutral period: 10 (B-CC B-C/-type) (D-CC, D-C/-type). then exposed stress at 37 °C (control, CON) 42 (heat stress, HS) 3 h. Following this, returned incubator 0, 3, 6, 12 h further recovery analysis. 2, (six times every days; threshold, mild, moderate levels) gene expression measured. Data analyzed via two-way analysis of variance (ANOVA) Tukey’s honestly significant difference (HSD) test. cell proliferation D-C/-group significantly higher (p < 0.05) than D-CC B-C/-groups 0 1 after HS mRNA greater 0.01) all groups compared CON exposure. B-CC immediately (0 h) following HS. group also B-C/-group. increased more level that threshold level. addition, overexpression noted D-C/-groups B-C/-groups. conclusion, our results indicate breeds polymorphisms exhibit distinctive pattern immune profiles. Additionally, may serve as an indicator across different breeds, making it potential novel barometer

Language: Английский

Citations

0
Association of two missense mutations in the MSS51 and KAT6B genes with body weight at different ages in cows of the Yaroslavl breed DOI Creative Commons
Alexander V. Igoshin, N. S. Yudin, Denis M. Larkin

et al.

Vavilov Journal of Genetics and Breeding, Journal Year: 2025, Volume and Issue: 29(1), P. 122 - 127

Published: March 4, 2025

The Yaroslavl cattle is a native Russian dairy breed developed in the 19th century from Northern Great cattle, which were adapted to withstand harsh climates and poor forage conditions. Previous studies identified two breed-specific missense mutations MSS51 (Ala415Glu) KAT6B (Val105Met) genes that negatively impact body weight of animals. This study aimed confirm association these genes, along with mutant haplotype containing both mutations, live at various ages using an expanded sample set. We genotyped 113 cows for variants analyzed their associations birth, as well 6, 10, 12, 15, 18 months combined 143 animals, includes earlier data. employed linear regression one-way ANOVA statistical analysis. results indicated significant mutation gene. gene was associated months. Notably, linked across all 6 One-way revealed genotypes only For haplotype, found In tests, most observed rather than individual variants. These findings could be instrumental enhancing beef hybrids utilising breed.

Language: Английский

Citations

0
Rethinking River Buffalo Domestication Through the Lens of Population Genetics Tools: Mehsana Buffalo Is a Unique Population DOI

Rangasai Chandra Goli,

Kiyevi G Chishi,

Karan Mahar

et al.

OMICS A Journal of Integrative Biology, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Riverine buffalo domestication likely occurred around 6300 years ago in Northwestern India. Murrah and Surti are important breeds that originated this region the gene flow from these buffaloes to Mehsana has long been proposed. However, extent which ancestry diffused across not investigated thoroughly. Therefore, we global local of Indian using double digest restriction-site associated DNA sequencing data. Principal component analysis, admixture dating, three population tests revealed with statistical significance is a unique population. Hence, hypothesis crossbreed between supported by findings. noticed some individuals Mehsana, 6 out 15, were admixed having 41% Murrah-specific 11% Surti-specific ancestry. Local post-admixture selection signatures (PASS) PASS genome, is, on Bubalus bubalis autosomes (BBA), 1-23 linked BBA, 24 Murrah. Interestingly, upon functional enrichment signatures, several adaptation-related genes pathways ascertained Surti, while Murrah-derived regions featured involved fatty acid synthesis (Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2)) milk production. Based infer introgression genome into happened recent times ancient generations. The finding an independent highlights importance recognizing distinct genetic lineages domesticated species. This implications for reevaluating origins uniqueness other livestock often assumed be hybrids. Practically, findings open up new avenues selective breeding preserve traits such as disease resistance, adaptability, production efficiency. Further studies larger samples called for.

Language: Английский

Citations

0
Adaptability of Polish Red cows to extensive conditions DOI Creative Commons
Witold Chabuz, Paweł Żółkiewski, Wioletta Sawicka-Zugaj

et al.

BMC Veterinary Research, Journal Year: 2025, Volume and Issue: 21(1)

Published: May 9, 2025

This study assessed the adaptive capacity of Polish Red cattle, one oldest indigenous dual-purpose breeds in Europe, to extensive environmental conditions north-eastern Poland. Twenty-two pregnant cows (average lactation number: 4.6) were divided into two groups: maintained a highly 'bale grazing' system (EXT), and other under traditional housing for suckler (TRAD). The experiment was conducted from onset winter through end subsequent pasture season. Parameters included changes body weight condition score (BCS), calf growth performance, milk yield, haematological biochemical blood indices. Statistical analysis performed using independent-samples t-tests Mann-Whitney U test (p ≤ 0.05, p 0.01). Despite challenging EXT group, including no shelter exposure variable climatic factors, health comparable TRAD group. While group calves showed superior (29 kg higher weight, 0.01), exhibited remarkable resilience by supporting survival with minimal loss 4.4 loss, less than 1% initial weight). Blood parameters remained within physiological ranges both groups, confirming breed's adaptability. These findings provide first experimental evidence adaptability cattle farming systems, highlighting their potential as valuable genetic resource sustainable livestock production increasing variability. conclusion has significant implications conservation biodiversity development climate-resilient breeding Europe.

Language: Английский

Citations

0