Vitamin D: An overview of vitamin D status and intake in Europe

Nutrition Bulletin, Journal Year: 2014, Volume and Issue: 39(4), P. 322 - 350

Published: Sept. 30, 2014

Abstract In recent years, there have been reports suggesting a high prevalence of low vitamin D intakes and deficiency or inadequate status in E urope. Coupled with growing concern about the health risks associated status, this has resulted increased interest topic from healthcare professionals, media public. Adequate key role skeletal health. Prevention well‐described disorders rickets osteomalacia are clearly important, but may also be an implication bone loss, muscle weakness falls fragility fractures older people, these highly significant public issues terms morbidity, quality life costs to services Although is no agreement on optimal plasma levels , it apparent that blood 25‐hydroxyvitamin [25( OH ) ] often below recommended ranges for general population particularly some subgroups population, such as those institutions who housebound non‐ W estern immigrants. Reported estimates within different uropean countries show large variation. However, comparison studies across urope limited by their use methodologies. The [often defined 25( )D <25 nmol/l] more common populations higher proportion at‐risk groups, and/or consumption foods rich (naturally fortified) supplements. definition adequate determining recommendations intake will enable satisfactory maintained all year round, including winter months. most countries, seems shortfall achieving current recommendations. An exception F inland, where dietary survey data indicate national policies include fortification supplementation, coupled habitual oil‐rich fish, increase intakes, not suitable strategy populations. ongoing standardisation measurements research facilitate stronger evidence base which can determined. These promotion recommendations, food fortification, supplementation judicious sun exposure, should take into account national, cultural habits. For nations policies, important relevant parties ensure uptake vulnerable groups population.

Language: Английский

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Nordic Nutrition Recommendations 2023

Nordic Council of Ministers eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 1, 2023

Pulses/legumes Nuts and seeds Fish seafood Red meat White Milk dairy products Eggs Fats

Language: Английский

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Vitamin D – a systematic literature review for the 5th edition of the Nordic Nutrition Recommendations

Food & Nutrition Research, Journal Year: 2013, Volume and Issue: 57(1), P. 22671 - 22671

Published: Jan. 1, 2013

Background: The present literature review is part of the NNR5 project with aim reviewing and updating scientific basis 4th edition Nordic Nutrition Recommendations (NNR) issued in 2004. Objectives: overall was to recent data on requirements health effects vitamin D report it Working Group, who responsible for current dietary reference values valid countries. Methods: electronic databases MEDLINE Swemed were searched. We formulated eight questions which used search. search terms related status intake different outcomes as well effect sources status. done two batches, first covering January 2000 March 2010 second 2009 February 2011. In search, we focused only systematic reviews (SLRs) SLRs randomized control trials (RCTs) published after 2009. Furthermore, snowballing IRCTs between 2011 May 2012. abstracts selected full-text papers evaluated pairs. Results: found 1,706 studies searches 28 included our review. 7 more by snowballing, thus 35 total. Of these studies, 31 4 RCTs. generally good or fair quality, whereas that varied from poor. heterogeneity large made difficult interpret results provide single summary statements. One factor increasing variation assays assessing 25-hydroxyvitamin concentration [25(OH)D], marker have reviewed conclude evidence a protective conclusive concerning bone health, total mortality risk falling. Moreover, often seen persons low basal 25(OH)D concentrations. addition, most intervention leading conclusions combined calcium not alone gives benefits. It establish an optimal based SLRs, but there are ≥50 nmol/l could be optimal. doseresponse relating (fortification supplementation) S-25(OH)D suggested 1-2.5 μg/day will increase serum 1-2 this dependent response being greater when low. Conclusion: Data show 50 would reflect sufficient Results support recommendation NNR 2004 needs re-evaluated increased all age groups beyond 2 years age. refer food supplements, given minimal sun exposure. Limited sunshine, however, does situation majority population summertime. should also emphasized differences depending assay methods laboratories measuring 25(OH)D, adding uncertainty determining appropriate target concentration. 25(OH)D-concentrations established concentrations, sunshine exposure intake. advise uncertainties taken into account setting final recommendations. Keywords: D; requirements; review; health; (Published: 3 October 2013) Citation: Food & Research 2013. 57: 22671 - http://dx.doi.org/10.3402/fnr.v57i0.22671 Access Appendices article – see Supplementary material under Article Tools online. Special Issue: This paper project. More issue can at http://www.foodandnutritionresearch.net

Language: Английский

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Scientific opinion on the tolerable upper intake level for vitamin B6

EFSA Journal, Journal Year: 2023, Volume and Issue: 21(5)

Published: May 1, 2023

Abstract Following a request from the European Commission, EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver scientific opinion tolerable upper intake level (UL) for vitamin B6. Systematic reviews of literature were conducted by contractor. The relationship between excess B6 intakes development peripheral neuropathy is well established critical effect which UL based. A lowest-observed-effect-level (LOAEL) could not be based human data. reference point (RP) 50 mg/day identified case–control study, supported data case reports vigilance An uncertainty factor (UF) 4 applied RP account inverse dose time onset symptoms limited available. latter covers uncertainties as that would represent LOAEL. This leads 12.5 mg/day. From subchronic study in Beagle dogs, LOAEL mg/kg body weight (bw) per day can identified. Using an UF 300, default bw 70 kg, 11.7 calculated. midpoint range these two ULs rounding down, 12 adults (including pregnant lactating women). infants children are derived using allometric scaling: 2.2–2.5 (4–11 months), 3.2–4.5 (1–6 years), 6.1–10.7 (7–17 years). Based available data, EU populations unlikely exceed ULs, except regular users food supplements containing high doses

Language: Английский

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Vitamin B6, B12, and Folate’s Influence on Neural Networks in the UK Biobank Cohort

Nutrients, Journal Year: 2024, Volume and Issue: 16(13), P. 2050 - 2050

Published: June 27, 2024

Background: One-carbon metabolism coenzymes may influence brain aging in cognitively unimpaired adults. Methods: Baseline data were used from the UK Biobank cohort. Estimated intake of vitamin B6, B12, and folate was regressed onto neural network functional connectivity five resting-state networks. Linear mixed models tested coenzyme main effects interactions with Alzheimer’s disease (AD) risk factors. Results: Increased B6 B12 estimated linked less most networks, including posterior portion Default Mode Network. Conversely, higher related to more similar AD family history modulated these associations: positively associated stronger Primary Visual Network Posterior participants an history. In contrast, increased Cerebello–Thalamo–Cortical those without Conclusions: The differential patterns association between B vitamins activity be important understanding AD-related changes brain. Notably, appears play a key role modulating relationships.

Language: Английский

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Nutritional adequacy of diets containing growing up milks or unfortified cow's milk in Irish children (aged 12–24 months)

Food & Nutrition Research, Journal Year: 2013, Volume and Issue: 57(1), P. 21836 - 21836

Published: Jan. 1, 2013

Growing up milks (GUM) are milk-based drinks with added vitamins and minerals intended for children aged 12-36 months. Few data available on the consumption of GUM their role in diets young children.

Language: Английский

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Impact of Regulatory Action on Dose Maximalization for Vitamin B6 Dietary Supplements on the Reporting Pattern for Neuropathy

Pharmacoepidemiology and Drug Safety, Journal Year: 2025, Volume and Issue: 34(2)

Published: Jan. 29, 2025

ABSTRACT Background Vitamin B6 deficiency is linked to neurological disorders. However, supplementation with high doses of vitamin has also been neuropathy as an adverse drug reaction. Review cases from the Dutch Spontaneous Reporting System (SRS) and other data led a regulatory action lower maximum daily dose (DD) in supplements 21 mg/day October 1, 2018. Purpose The aim this study was investigate if there effect 2018 on dosage for reporting pattern SRS Netherlands. Methods We investigated trends number reports received until December 31, 2023, DD mentioned reports, correlation between plasma levels. A change point analysis used get insight into over time. Results Two hundred twenty‐four were included. After maximization 2018, only one report mentions which much higher than recommended mg DD. Only 15% variability levels can be explained by Twelve statistical points noted, especially around some peaks instance second half 2019, per time period no detected. Conclusions Although our limitations, we clearly see reports. describing related are still reported after Therefore, association low‐dose products should studied further.

Language: Английский

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Vitamin D Dietary Intake Questionnaire Validation Conducted among Young Polish Women

Nutrients, Journal Year: 2016, Volume and Issue: 8(1), P. 36 - 36

Published: Jan. 5, 2016

Due to inadequate intake of Vitamin D, identification individuals characterised by the highest risk deficiencies is one more crucial tasks for public health. The aim presented study was assess validity and reproducibility designed D dietary questionnaire based on food frequency assessment--VIDEO-FFQ (VItamin Estimation Only--Food Frequency Questionnaire) in a group Polish women aged 20-30 years. Seventy-five participants kept three-day record filled out VIDEO-FFQ twice (immediately after six weeks). assessment conducted verifying standard errors estimation, median differences, percentages classified into tertiles, correlations Bland-Altman plots. majority surveyed as over 85% them were values lower than 5.0 μg per day. results allowed concluding that high accuracy achieved. required index 5.0% obtained, confirming satisfactory reproducibility. may be deemed convenient practical tool estimation young women.

Language: Английский

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Polyneuropathy due to Vitamin B6 hypervitaminosis: A case series and call for more education

Journal of Neurosciences in Rural Practice, Journal Year: 2025, Volume and Issue: 16, P. 99 - 103

Published: Feb. 14, 2025

Polyneuropathy (PN) due to Vitamin B6 hypervitaminosis is well described in medical literature. However, only little known about this relationship among the general population as under health care professionals. The following describes eight consecutively recruited patients: Seven of whom developed sensorimotor PN uncritical medication, and one patient who experienced a worsening pre-existing another etiology associated with B6. Due fact that B6-induced preventable disease, we strongly advocate for increased awareness education practitioners. It crucial understand taking vitamin supplements not always beneficial can be serious side effects.

Language: Английский

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Assessment of the potential nutritional value of cell-cultured chicken meat in light of European dietary recommendations

Journal of Food Composition and Analysis, Journal Year: 2024, Volume and Issue: 135, P. 106663 - 106663

Published: Aug. 16, 2024

Language: Английский

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