International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 667, P. 124898 - 124898
Published: Nov. 3, 2024
Language: Английский
Bioengineering, Journal Year: 2025, Volume and Issue: 12(1), P. 38 - 38
Published: Jan. 7, 2025
Bone is a natural mineral-organic nanocomposite protecting internal organs and allowing mobility. Through the ages, numerous strategies have been developed for repairing bone defects fixing fractures. Several generations of repair biomaterials proposed, either based on metals, ceramics, glasses, or polymers, depending clinical need, maturity technologies, knowledge constitution tissue to be repaired. The global trend in implant research shifting toward osteointegrative, bioactive possibly stimuli-responsive and, where possible, resorbable implants that actively promote regeneration tissue. In this mini-review, fundamentals healing materials challenges are summarized commented with regard progressing scientific discoveries. main types bone-healing then reviewed, their specific relevance field reminded, citation reference works. final part, we highlight promise hybrid organic-inorganic ongoing activities development multifunctional implants. This contribution expected serve as introduction ever-progressing trends future-oriented research.
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155139 - 155139
Published: Aug. 24, 2024
Language: Английский
Citations
8
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: July 27, 2024
Abstract Regenerative biomedicine has emerged as a forefront area in medical research, heralding new era of therapeutic strategies. This review delineates the integration 2D materials (2DMs) within biomedical engineering, leveraging their superior physicochemical attributes for enhance outcomes. The synergistic interaction between biomacromolecules and 2DMs is explored, demonstrating potential to mitigate limitations inherent each while simultaneously augmenting beneficial properties. In particular, incorporating into hydrogels highlights capability mechanical strength hydrogels, providing biomimetic scaffold tissue engineering regeneration cancer diagnosis therapy. An overview synthetic methodologies are provided 2DMs, elucidating dynamics with biomacromolecules. primarily concentrates on applications biomacromolecule‐reinforced 2DM across various fields, including bone wound healing, neural cardiac well delivery drugs genes, therapy, biosensing technologies. Finally, discusses existing challenges future outlook developing using underlining transformative regenerative medicine.
Language: Английский
Citations
7
Chemical Communications, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
This review discusses design strategies for external stimuli-driven hydrogels with in situ catalytic processes. It highlights precise control over the properties, elucidating regulatory mechanisms and deepening understanding of applications.
Language: Английский
Citations
0
Rare Metals, Journal Year: 2025, Volume and Issue: unknown
Published: March 14, 2025
Language: Английский
Citations
0
Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114704 - 114704
Published: April 1, 2025
Language: Английский
Citations
0
Bone, Journal Year: 2024, Volume and Issue: 190, P. 117315 - 117315
Published: Nov. 4, 2024
Tissue engineering employs the use of bioactive materials to facilitate filling and acceleration bone defect healing, thereby introducing novel concepts field in situ repair. Some studies have shown that periosteum plays an important role regeneration In this study, biomimetic periosteum-bone scaffolds were prepared by depositing poly-L-lactic acid (PLLA) electrospun fibers on surface gelatin/chitosan cryogel mimic structure, respectively. To improve bioactivity scaffold, morphogenetic protein-2 (BMP-2) was loaded into a loose porous mesh-like cryogel, while platelet-derived growth factor-BB (PDGF-BB) encapsulated core PLLA nanofibers with core-shell structure. Both these two factors released locally at site defect, where they exert synergistic effect osteogenesis, greatly accelerating healing. The vitro experiments demonstrated exhibited favourable biocompatibility osteogenesis ability. Furthermore, vivo indicated composite scaffold repaired rat skull defects more rapid effective manner. conclusion, codelivery BMP-2 PDGF-BB shows significant potential for regeneration.
Language: Английский
Citations
3
International Endodontic Journal, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 6, 2025
Abstract Stimuli‐responsive hydrogels are smart and functional materials that respond to various environmental stimuli, including temperature, light, magnetic field, pH, redox, enzymes glucose. This responsiveness allows for the controlled release of therapeutic agents encapsulated within hydrogels, enhancing treatment precision, improving outcomes minimizing side effects. Such show great potential in root canal disinfection, management dental pulp inflammation regeneration, making them promising candidates more personalized effective endodontic treatments. article provides an overview latest advancements design application stimuli‐responsive endodontics, emphasizing their revolutionize It also addresses current challenges explores future directions aiming inspire motivate researchers further engage or intensify efforts this area research.
Language: Английский
Citations
0
Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Bone defects resulting from trauma, tumors, or other injuries significantly impact human health and quality of life. However, current treatments for bone are constrained by donor shortages immune rejection. tissue engineering has partially alleviated the limitations traditional repair methods. The development smart biomaterials that can respond to external stimuli modulate biofunctions become a prominent area research. Ultrasound technology is regarded as an optimal "remote controller" "trigger" biomaterials. This review reports comprehensive systematic overview ultrasound-responsive It presents fundamental theories repair, definition ultrasound, its applications. Furthermore, summarizes ultrasound effect mechanisms their roles in including detailed studies on anti-inflammation, immunomodulation, cell therapy. Finally, advantages future prospects this field discussed.
Language: Английский
Citations
0
Stomatology, Journal Year: 2024, Volume and Issue: 103(6), P. 58 - 58
Published: Jan. 1, 2024
The review considers methods of manufacturing photopolymerizable compositions for bone tissue repair, as well polymers and photoinitiators used this purpose. Their physical biological properties are described. Examples light-curing in biomedicine engineering given. prospects photopolymerization development the production materials regeneration a promising technology application dentistry, maxillofacial surgery orthopedics considered.
Language: Английский
Citations
0