Smart Digital Solutions for EARLY Treatment of COGNitive Disability (EARLY-COGN^3): A Study Protocol DOI Creative Commons
Maria Cotelli, Francesca Baglio, Elena Gobbi

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 239 - 239

Published: Feb. 24, 2025

Background: Healthy cognitive functioning is a primary component of well-being, independence, and successful aging. Cognitive deficits can arise from various conditions, such as brain injury, mental illness, neurological disorders. Rehabilitation highly specialized service limited to patients who have access institutional settings. In response this unmet need, telehealth solutions are ideal for triggering the migration care clinics patients’ homes. Objectives: The aim EARLY-COGN^3 will be threefold: (1) test efficacy digital health at-home intervention (tele@cognitive protocol) compared an unstructured rehabilitation in cohort with Chronic Neurological Diseases (CNDs); (2) investigate its effects on biomolecular neurophysiological marker hypothesizing that people CNDs enrolled telerehabilitation program develop changes biological markers cortical subcortical patterns connectivity; (3) analyze potential cognitive, neurobiological, predictors tele@cognitive treatment. Method: single-blind, randomized, controlled pilot study, we assess short- long-term protocol (tele@cognitive) (Active Control Group—ACG) 60 Mild Impairment (MCI), Subjective Complaints (SCCs), or Parkinson’s Disease (PD). All participants undergo clinical, functional, neurocognitive, quality life assessment at baseline (T0), post-treatment (5 weeks, T1), 3-month (T2) follow-up. Neurophysiological data collected T0 T1. Conclusions: project could lead complete paradigm shift traditional therapeutic approach, forcing reassessment how take advantage solution. (clinicaltrials.gov database, ID: NCT06657274)

Language: Английский

Smart Digital Solutions for EARLY Treatment of COGNitive Disability (EARLY-COGN^3): A Study Protocol DOI Creative Commons
Maria Cotelli, Francesca Baglio, Elena Gobbi

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 239 - 239

Published: Feb. 24, 2025

Background: Healthy cognitive functioning is a primary component of well-being, independence, and successful aging. Cognitive deficits can arise from various conditions, such as brain injury, mental illness, neurological disorders. Rehabilitation highly specialized service limited to patients who have access institutional settings. In response this unmet need, telehealth solutions are ideal for triggering the migration care clinics patients’ homes. Objectives: The aim EARLY-COGN^3 will be threefold: (1) test efficacy digital health at-home intervention (tele@cognitive protocol) compared an unstructured rehabilitation in cohort with Chronic Neurological Diseases (CNDs); (2) investigate its effects on biomolecular neurophysiological marker hypothesizing that people CNDs enrolled telerehabilitation program develop changes biological markers cortical subcortical patterns connectivity; (3) analyze potential cognitive, neurobiological, predictors tele@cognitive treatment. Method: single-blind, randomized, controlled pilot study, we assess short- long-term protocol (tele@cognitive) (Active Control Group—ACG) 60 Mild Impairment (MCI), Subjective Complaints (SCCs), or Parkinson’s Disease (PD). All participants undergo clinical, functional, neurocognitive, quality life assessment at baseline (T0), post-treatment (5 weeks, T1), 3-month (T2) follow-up. Neurophysiological data collected T0 T1. Conclusions: project could lead complete paradigm shift traditional therapeutic approach, forcing reassessment how take advantage solution. (clinicaltrials.gov database, ID: NCT06657274)

Language: Английский

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