Depressive Symptoms and Mortality Among US Adults

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(10), P. e2337011 - e2337011

Published: Oct. 9, 2023

Depression is a common mental health disorder in the US. Depressive symptoms have been associated with increased cardiovascular disease incidence and mortality, but studies largely focused on narrow population subgroups.To examine association between depressive mortality large, diverse, nationally representative sample of US adults, to how lifestyle factors mediate this association.This was prospective cohort study adults using National Health Nutrition Examination Survey 2005 2018 data linked Death Index through 2019 for aged 20 years older. Data were analyzed March 1 May 26, 2023.All-cause, disease, ischemic heart mortality. defined by Patient Questionnaire-9 scores categorized as none or minimal, mild, moderate severe. Secondarily, we assessed degree mediation factors.A total 23 694 participants included (unweighted n = 11 862 male [weighted 49.8%]; mean [SE] age, 44.7 [0.24] years). Prevalences mild severe depression 14.9% 7.2%, respectively. For all-cause hazard ratios 1.35 (95% CI, 1.07-1.72) vs 1.62 1.24-2.12) none. The corresponding 1.49 1.11-2.00) 1.79 1.22-2.62) 0.96 0.58-1.60) 2.21 1.24-3.91) associations consistent across subgroups. Approximately 11.0% 16.1% could be explained factors. Feeling tired having little energy, poor appetite overeating, interest doing things independently not mortality.In there graded positive Public efforts improve awareness treatment risk support comprehensive, nationwide strategy reduce burden depression.

Language: Английский

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Dietary Nutrient Deficiencies and Risk of Depression (Review Article 2018–2023)

Nutrients, Journal Year: 2023, Volume and Issue: 15(11), P. 2433 - 2433

Published: May 23, 2023

Depression is classified as one of the most common mental disorders. Its prevalence has recently increased, becoming a growing public health threat. This review focuses on clarifying role and importance individual nutrients in diet impact nutrient deficiencies risk depression. Deficiencies such protein, B vitamins, vitamin D, magnesium, zinc, selenium, iron, calcium, omega-3 fatty acids have significant brain nervous system function, which can affect appearance depressive symptoms. However, it important to remember that itself not only factor influencing or helping treat There are many other aspects, physical activity, sleep, stress management, social support, also play an maintaining health. The data observed available analyses based cross-sectional studies. Further studies, including prospective cohort, case-control recommended draw more reliable conclusions.

Language: Английский

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Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry

Cells, Journal Year: 2024, Volume and Issue: 13(10), P. 790 - 790

Published: May 7, 2024

Translational research in neurological and psychiatric diseases is a rapidly advancing field that promises to redefine our approach these complex conditions [...]

Language: Английский

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A Comprehensive Analysis of Mental Health Problems in India and the Role of Mental Asylums

Cureus, Journal Year: 2023, Volume and Issue: unknown

Published: July 27, 2023

This review article provides a comprehensive overview of the current state mental health in India, highlighting challenges faced, existing initiatives, and future directions for improving healthcare delivery. India is grappling with high prevalence disorders, including depression, anxiety bipolar disorder, schizophrenia, substance use disorders. The burden issues on individuals, families, society immense, leading to reduced quality life, impaired functioning, significant economic social consequences. Various cultural factors, such as stigma, discrimination, gender inequalities, poverty, rapid urbanization, beliefs surrounding illness, further exacerbate addressing problems. Access remains concern, considerable gaps access treatment limited availability professionals, especially rural areas. Inadequate infrastructure, lack awareness, insufficient integration into primary systems hinder appropriate care. historical development asylums examined, their establishment, purpose, evolution over time. Critiques associated are discussed, stigmatization, human rights concerns, absence center approaches, care, need alternative approaches healthcare.

Language: Английский

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Editorial: Towards a mechanistic understanding of depression, anxiety, and their comorbidity: perspectives from cognitive neuroscience

Frontiers in Behavioral Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Aug. 15, 2023

EDITORIAL article Front. Behav. Neurosci., 15 August 2023Sec. Emotion Regulation and Processing Volume 17 - 2023 | https://doi.org/10.3389/fnbeh.2023.1268156

Language: Английский

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A comprehensive examination of mental health in patients with head and neck cancer: systematic review and meta-analysis

JNCI Cancer Spectrum, Journal Year: 2024, Volume and Issue: 8(3)

Published: April 30, 2024

Abstract Background Patients with head and neck cancer present particularly considerable levels of emotional distress. However, the actual rates clinically relevant mental health symptoms disorders among this population remain unknown. Methods A Preferred Reporting Items for Systematic Review Meta-Analyses Meta-analyses Observational Studies in Epidemiology–compliant systematic review quantitative random-effects meta-analysis was performed to determine suicide incidence prevalence depression, anxiety, distress, posttraumatic stress, insomnia population. MEDLINE, Web Science, Cochrane Central Register, KCI Korean Journal database, SciELO, Russian Science Citation Index, Ovid-PsycINFO databases were searched from database inception August 1, 2023 (PROSPERO: CRD42023441432). Subgroup analyses meta-regressions investigate effect clinical, therapeutical, methodological factors. Results total 208 studies (n = 654 413; median age 60.7 years; 25.5% women) identified. Among patients, 19.5% reported depressive (95% confidence interval [CI] 17% 21%), 17.8% anxiety CI 14% 34.3% distress 29% 39%), 17.7% 6% 41%), 43.8% 35% 52%). Diagnostic criteria assessments revealed lower disorders: 10.3% depression 7% 13%), 5.6% 2% 10%), 9.6% 1% 40%), stress 0% 84.5%). Suicide pooled 161.16 per 100 000 individuals year 82 239). Meta-regressions found a statistically significant higher patients undergoing primary chemoradiation compared surgery increased smokers advanced tumor staging. European samples exhibited Conclusions presented notable concerns all domains. remains highly concern. The criteria-meeting is significantly than symptoms. Investigating effectiveness targeted symptomatic essential.

Language: Английский

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Decomposing the rural–urban differences in depression among multimorbid older patients in India: evidence from a cross-sectional study

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 22, 2024

Abstract Background In India, the prevalence of depression among older adults dealing with multiple health conditions varies between rural and urban areas due to disparities in healthcare access cultural factors. The distinct patterns observed underscore necessity for tailored research interventions address mental inequalities multimorbid patients diverse geographic contexts. Methods This study used data from Longitudinal Ageing Study India (LASI) wave 1 (2017–18). A total 7,608 aged ≥ 60 years who were diagnosed two or more chronic (such as hypertension, diabetes, cancer, lung disease, heart diseases, stroke, bone/joint any neurological psychiatric high cholesterol) included this study. Descriptive statistics, bivariate analysis, logistic regression estimates, Fairlie decomposition method accomplish study’s objectives. Results multimorbidity was 9.48% higher (38.33%) than (28.85%).. Older belonging scheduled caste group 40% likely experience depression. Moreover, those form disability activities daily living (ADL) 93% without disability, whereas perceived good general 65% less suffer poor self-perceived health. Additionally, analysis revealed that education (35.99%), status (10.30%), IADL (19.30%), discrimination (24.25%) primary factors contributing differences areas. Conclusions We found significant rural–urban Indians multimorbidity. findings need targeted unique challenges faced by areas, including lack social capital, discrimination, limited resources enable services. Policymakers professionals must collaboratively design implement effective strategies improve overall well-being adults, particularly comorbidities.

Language: Английский

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Sex differences in the inflammation-depression link: A systematic review and meta-analysis

Brain Behavior and Immunity, Journal Year: 2024, Volume and Issue: 121, P. 257 - 268

Published: July 30, 2024

Major Depressive Disorder (MDD) is a heterogeneous disorder that affects twice as many women than men. Precluding advances in more tailored and efficacious treatments for depression the lack of reliable biomarkers. While linked to elevations inflammatory immune system functioning, this relationship not evident among all individuals with may vary based on symptom subtypes and/or sex. This systematic review meta-analysis examined whether peripheral markers are sex-specific. PRISMA guidelines were followed review, comprehensive search strategy identified studies from PubMed PsycInfo was applied. Studies included if they reported C-reactive protein (CRP), interleukin (IL)-6, tumor necrosis factor (TNF)-α IL-1β males females depressed healthy adults. We 23 satisfied these inclusion criteria. Random-effects models fit, measures association summarized between levels circulating inflammation females. Sex-based analyses revealed elevated CRP (Cohen's d = 0.19) relative their counterparts (p 0.02), an effect apparent -0.01). Similarly, IL-6 increased compared controls 0.51; p 0.04), but once again found 0.16). TNF-α 0.01), no statistically significant sex differences found. The resulted only three articles, thus, results presented supplemental section. our understanding unique involvement biomarkers men women, which help inform sex-specific treatment approaches future.

Language: Английский

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Dirty Environment, Dark Mood: Exploring the Link Between Perceived Environmental Pollution and Depression Risk

Journal of Community Psychology, Journal Year: 2025, Volume and Issue: 53(1)

Published: Jan. 1, 2025

To explore the impact of perceived environmental pollution on individual depression risk and mechanisms involved, particularly mediating roles health level life confidence. Ordinary least squares, Ologit, Oprobit models were employed to analyze data from 2020 China Family Panel Studies test hypothesized relations outlined above. The findings indicate that significantly increases (β = 0.052, p < 0.01). Both confidence serve as mediators in this relationship, forming a serial mediation mechanism. This study reveals negative mental health. It emphasizes importance improving public levels provides an evidence base for related policies.

Language: Английский

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Prevalence of depression and its correlates among undergraduate health science students in Mogadishu, Somalia: a cross-sectional study

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 1, 2025

Abstract Background Depression among undergraduate health science students is increasingly recognized as a significant public issue globally. These face immense academic pressure, often leading to stress and mental exhaustion, particularly for studying in humanitarian crisis situation. However, there scarcity of information this regard higher education institutions Somalia. Hence, investigation was conducted assess the prevalence depression its correlates Methods A cross-sectional study on 321 from some universities Mogadishu, The data collected medicine, nursing midwifery, laboratory at SIMAD university, Banadir Mogadishu university Jamhuriya all located Mogadishu. Simple random sampling based class list used select participants web-based self-administered Patient Health Questionnaire (PHQ-9) screen depression. were cleaned checked completeness before exporting into SPSS version 27 Statistical software analysis, where descriptive statistics well logistic regression analysis done determine independent predictors outcome variable. Significant association determined 95% confidence interval p -value < 0.05. Result 58.6%. total 41.5% (133/321) free (Normal), while 30.8% had mild depression, 27.1% moderate 0.6% severe Analysis between sociodemographic variables depressive state participant showed statistical significance ( = 0.045) course study. Students midwifery highest case with 68.6% (59/86), followed by 66.7% (30/45), 52.3% (34/65), medicine having least number depressed 52.0% (65/125). Similarly, gender also found be statistically 0.001) female 65% which 41.1% studied. Conclusion high positively associated gender, trouble authorities, emotional problems, experience sexual abuse or violence. routine screening monitoring students’ campus providing services necessary address growing problem.

Language: Английский

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