Lactoferrin as a Versatile Agent in Nanoparticle Applications: From Therapeutics to Agriculture DOI Creative Commons
Emir Akdaşçi, Furkan Eker, Hatice Duman

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(24), P. 2018 - 2018

Published: Dec. 16, 2024

Nanoparticles (NPs) have emerged as a potent choice for various applications, from drug delivery to agricultural studies, serving an alternative and promising methodology future advancements. They been widely explored in systems, demonstrating immense promise high efficiency the of numerous biomolecules such proteins anticancer agents, either solely or modified with other compounds enhance their capabilities. In addition, utilization NPs extends antimicrobial where they are used develop novel antibacterial, antifungal, antiviral formulations advanced characteristics. Lactoferrin (Lf) is glycoprotein recognized its significant multifunctional properties, antimicrobial, antioxidant, anti-inflammatory, anticancer, neuroprotective effects. Its activity has broad distribution human body, Lf receptors present multiple regions. Current research shows that utilized NP technology surface material, encapsulated biomolecule, even itself. Due abundance regions, can be employed material targeted strategies, particularly crossing BBB targeting specific cancers. Furthermore, synthesized structure, positioning it strong candidate NP-related applications. this article, we explore highlighted underexplored areas applications research.

Language: Английский

Impact of gold nanoparticle exposure on the development pancreas and kidney: Dose-dependent;oxidative stress; miRNA expression and Nrf2/ARE Signalling DOI

Hanan M. A. El Henafy,

Mansour A. Alghamdi, Hind Zafrah

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 152, P. 114409 - 114409

Published: March 11, 2025

Language: Английский

Citations

0
Nanoparticle-Based Delivery Systems for Phytochemicals in Cancer Therapy: Molecular Mechanisms, Clinical Evidence, and Emerging Trends DOI
Mahmoud A.H. Mostafa, Hani M. J. Khojah

Drug Development and Industrial Pharmacy, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 31

Published: March 21, 2025

This review examines recent advancements in nanoparticle-based delivery systems for phytochemicals, focusing on their role overcoming multidrug resistance, improving therapeutic efficacy, and facilitating clinical translation. highlights advances nanoparticle-enabled phytochemical to enhance bioavailability, improve outcomes, enable targeted applications. By comparing various nanoparticle systems, formulation methods, efficacy data, it identifies gaps current research guides the development of more effective, next-generation phytochemical-loaded nanocarriers. A systematic literature published between 2000 2024 was conducted using PubMed, Scopus, Web Science. Articles cancer therapy were included. Compounds such as curcumin, resveratrol, quercetin, epigallocatechin gallate demonstrate enhanced anti-cancer when encapsulated nanoparticles, leading improved increased tumor cell targeting, reduced toxicity. Clinical trials indicate regression fewer adverse effects. Emerging approaches-such nanogels, hybrid combination therapies with immune checkpoint inhibitors-further refine treatment efficacy. Nanoparticle-based significantly potential making them promising candidates safer, effective treatments. However, challenges related regulatory guidelines, scalability, long-term safety must be addressed fully realize potential.

Language: Английский

Citations

0
Eco-friendly Nanoparticle Phytosynthesis via Plant Extracts: Mechanistic Insights, Recent Advances, and Multifaceted Uses DOI Creative Commons
Great Iruoghene Edo, Alice Njolke Mafe,

Ali B.M. Ali

et al.

Nano TransMed, Journal Year: 2025, Volume and Issue: unknown, P. 100080 - 100080

Published: March 1, 2025

Language: Английский

Citations

0
Assessment of nanoparticles and algae as mediators with Trifolium sp. for the assembly of biosolar cells DOI Creative Commons
Ayesha Alam, Arifa Tahir, Faiza Anum

et al.

Next Sustainability, Journal Year: 2025, Volume and Issue: 5, P. 100120 - 100120

Published: Jan. 1, 2025

Language: Английский

Citations

0
Lactoferrin as a Versatile Agent in Nanoparticle Applications: From Therapeutics to Agriculture DOI Creative Commons
Emir Akdaşçi, Furkan Eker, Hatice Duman

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(24), P. 2018 - 2018

Published: Dec. 16, 2024

Nanoparticles (NPs) have emerged as a potent choice for various applications, from drug delivery to agricultural studies, serving an alternative and promising methodology future advancements. They been widely explored in systems, demonstrating immense promise high efficiency the of numerous biomolecules such proteins anticancer agents, either solely or modified with other compounds enhance their capabilities. In addition, utilization NPs extends antimicrobial where they are used develop novel antibacterial, antifungal, antiviral formulations advanced characteristics. Lactoferrin (Lf) is glycoprotein recognized its significant multifunctional properties, antimicrobial, antioxidant, anti-inflammatory, anticancer, neuroprotective effects. Its activity has broad distribution human body, Lf receptors present multiple regions. Current research shows that utilized NP technology surface material, encapsulated biomolecule, even itself. Due abundance regions, can be employed material targeted strategies, particularly crossing BBB targeting specific cancers. Furthermore, synthesized structure, positioning it strong candidate NP-related applications. this article, we explore highlighted underexplored areas applications research.

Language: Английский

Citations

0