Biochemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 8, 2024
Brain
organoid
implications
have
opened
vast
avenues
in
the
realm
of
interdisciplinary
research,
particularly
growing
field
intelligence
(OI).
A
brain
is
a
three-dimensional
(3D),
lab-grown
structure
that
mimics
certain
aspects
human
organization
and
function.
The
integration
technology
with
computational
methods
to
enhance
understanding
behavior
predict
their
responses
various
stimuli
known
as
OI.
ability
organoids
adapt
memorize,
key
area
exploration.
OI
encapsulates
confluence
breakthroughs
stem
cell
technology,
bioengineering,
artificial
(AI).
This
chapter
delves
deep
into
myriad
potentials
OI,
encompassing
an
enhanced
cognitive
functions,
achieving
significant
biological
proficiencies.
Such
advancements
stand
offer
unique
complementarity
conventional
computing
methods.
sphere
signify
transformative
stride
towards
more
intricate
grasp
its
multifaceted
intricacies.
intersection
biology
machine
learning
rapidly
evolving
reshaping
our
life
health.
convergence
driving
numerous
areas,
including
genomics,
drug
discovery,
personalized
medicine,
synthetic
biology.
MedComm,
Journal Year:
2024,
Volume and Issue:
5(10)
Published: Sept. 23, 2024
Bioprinting
is
a
highly
promising
application
area
of
additive
manufacturing
technology
that
has
been
widely
used
in
various
fields,
including
tissue
engineering,
drug
screening,
organ
regeneration,
and
biosensing.
Its
primary
goal
to
produce
biomedical
products
such
as
artificial
implant
scaffolds,
tissues
organs,
medical
assistive
devices
through
software-layered
discrete
numerical
control
molding.
Despite
its
immense
potential,
bioprinting
still
faces
several
challenges.
It
requires
concerted
efforts
from
researchers,
engineers,
regulatory
bodies,
industry
stakeholders
are
principal
overcome
these
challenges
unlock
the
full
potential
bioprinting.
This
review
systematically
discusses
principles,
applications,
future
perspectives
while
also
providing
topical
overview
research
progress
over
past
two
decades.
The
most
recent
advancements
comprehensively
reviewed
here.
First,
printing
techniques
methods
summarized
along
with
related
bioinks
supporting
structures.
Second,
interesting
representative
cases
regarding
applications
biosensing
introduced
detail.
Finally,
remaining
suggestions
for
directions
proposed
discussed.
one
areas
fields.
aims
devices.
perspectives,
which
provides
description
Applied Sciences,
Journal Year:
2025,
Volume and Issue:
15(8), P. 4216 - 4216
Published: April 11, 2025
In
recent
years,
additive
manufacturing
technologies
have
been
employed
for
ecological
projects,
especially
those
connected
with
artificial
reefs.
This
approach
brings
a
lot
of
advantages,
including
the
design
more
complex
structures,
surfaces
fitted
to
needs
water
organisms.
technology
can
effectively
support
and
engineering,
in
restoration
efforts.
The
main
aim
this
article
is
demonstrate
state
art
further
perspectives
development
coral
based
on
critical
analysis
literature,
supported
by
selected
case
studies.
describes
current
used
creation
reefs,
putting
emphasis
manufacturing,
evaluates
currently
materials,
summarizes
influence
ecosystems
through
It
also
discusses
challenges
limitations
3D
printing
reefs
as
well
presents
trends
directions.
most
important
findings
show
that
analyzed
field
promising
interdisciplinary
research
area
practical
implementations
require
collaboration
between
specialists
from
different
branches.
This
perspective
focuses
on
the
potential
of
artificial
intelligence
(AI)
in
craniomaxillofacial
(CMF)
bone
tissue
engineering,
mitigating
current
challenges,
and
driving
development
tailored
biomaterials
clinical
translation.
CMF
engineering
faces
significant
challenges
due
to
complexity
defects,
limitations
traditional
grafting
methods,
need
for
precise
anatomical
reconstruction.
AI
is
revolutionizing
by
leveraging
vast
computational
power
analyze
complex
biological
data,
optimize
treatment
strategies,
enhance
next-generation
regenerative
solutions.
facilitates
customization
scaffolds
patient-specific
enables
implementation
drug
delivery
systems
controlled
therapeutic
release,
drives
innovative
with
improved
biocompatibility,
enhances
reproducibility
precision
scaffold
fabrication,
advances
new
additive
technologies,
such
as
AI-driven
3D
4D
printing,
manufacturing
accuracy
efficiency.
Furthermore,
accelerates
diagnostics
predictive
modeling,
enabling
more
effective
decision-making
planning
improving
long-term
outcomes.
Required
standardized,
updated
protocols
significantly
improve
transparency
effectively
bridge
gap
between
preclinical
research
application,
ensuring
consistent
validation
translation
innovations.
By
integrating
medicine,
paving
way
personalized
efficient
solutions
reconstruction,
offering
transformative
advancements
patient
care
shaping
future
medicine
therapies.
Cyborg and Bionic Systems,
Journal Year:
2025,
Volume and Issue:
6
Published: Jan. 1, 2025
Tissues
larger
than
400
μm
in
size
lacking
microvascular
networks
cannot
survive
for
long
periods
of
time
vitro.
The
development
microfluidic
technology
provides
an
efficient
research
tool
constructing
models
However,
traditional
single-layer
chips
faced
the
limitation
spatial
layout
and
could
not
provide
diverse
fluidic
environments
within
a
single
chip.
In
this
paper,
we
present
novel
chip
design
with
3-layer
configuration
that
utilizes
polycarbonate
(PC)
porous
membrane
to
separate
culture
fluid
channels
from
tissue
chambers,
featuring
flexibly
designable
multitissue
chambers.
PC
membranes
act
as
capillary
vertical
direction,
enabling
precise
hydrogel
patterning
successfully
environment
suitable
growth.
demonstrates
ability
build
different
shapes
such
triangle,
rectangle,
inverted
triangle
on
more
10
days.
cultured
12
days
were
perfused
70-kDa
fluorescein
isothiocyanate,
which
indicated
generated
had
good
barrier
properties.
A
correlation
between
chamber
shape
shear
stress
was
demonstrated
using
COMSOL,
preliminary
validation
flow
direction
interstitial
important
effect
growth
by
vascularization
experiments.
This
flexible
scalable
is
ideal
culturing
multiple
vascularized
organ
tissues
chip,
well
studying
effects
factors
Journal of Applied Polymer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 13, 2025
ABSTRACT
Polypropylene
is
one
of
the
most
widely
used
industrial
thermoplastics,
which,
despite
its
high
consumption
in
various
industries,
especially
packaging,
not
much
emerging
field
3D
printing.
In
this
article,
for
first
time,
PETG
three
weight
percentages
55%,
70%,
and
85%
to
enhance
polypropylene's
printability,
mechanical
properties,
shape
memory
effect.
The
results
properties
showed
that
increase
continuously
with
amount
PETG,
blend
containing
has
highest
tensile
strength
(22.6
MPa)
Young's
modulus
(4.93
GPa).
This
also
a
better
behavior,
recovery
90%
less
than
10
s,
it
suitable,
cheap,
recyclable
option
be
added
4D
printing
library.
On
other
hand,
lowest
(55%)
acceptable
(17.45
(80%)
excellent
formability
(100%
elongation),
which
makes
ideal
applications
such
as
actuators
flexible
textiles.
SEM
DMTA
indicated
biphasic
structure
PETG–PP
blends
good
compatibility.
Also,
printability
all
played
significant
role
achieving
Medicine,
Journal Year:
2025,
Volume and Issue:
104(12), P. e41946 - e41946
Published: March 21, 2025
Three-dimensional
(3D)
printing
technology
has
emerged
as
a
revolutionary
tool
in
orthopedic
trauma
surgery,
offering
unprecedented
opportunities
for
personalized
patient
care.
This
comprehensive
review
explores
the
current
developments
and
applications
of
3D
trauma,
highlighting
its
potential
to
address
complex
surgical
challenges.
We
provide
an
in-depth
analysis
various
technologies
applicable
including
vat
photopolymerization,
material
extrusion,
powder
bed
fusion,
sheet
lamination.
The
examines
use
preoperative
planning,
simulation,
creation
patient-specific
implants
guides.
discuss
across
different
anatomical
regions,
upper
limb,
lower
pelvic
spinal
trauma.
Evidence
from
recent
studies
demonstrates
that
printing-assisted
surgeries
can
lead
reduced
operative
times,
decreased
blood
loss,
improved
fracture
reduction
quality,
potentially
better
clinical
outcomes.
synthesizes
latest
research
experiences,
providing
insights
into
state
future
perspectives.
As
continues
evolve,
holds
promise
increasingly
effective
treatments
care,
transforming
practices
improving
