Nanotechnology and Precision Engineering,
Journal Year:
2024,
Volume and Issue:
8(2)
Published: Oct. 21, 2024
Planar
positioning
systems
are
widely
utilized
in
micro
and
nano
applications.
The
challenges
modeling
control
of
XYΘ
flexure-based
mechanisms
include
hysteresis
the
piezoelectric
actuators,
couplings
among
input
axes,
coupled
linear
angular
motions
end
effector.
This
paper
presents
an
inverse
hysteresis-coupling
hybrid
model
to
account
for
such
couplings.
First,
a
specially
designed
kinematic
chain
is
adopted
transfer
pose
effector
into
at
three
prismatic
joints.
Second,
developed
linearize
decouple
system
via
multilayer
feedforward
neural
network.
A
fractional-order
PID
controller
also
integrated
improve
motion
accuracy
overall
system.
Experimental
results
demonstrate
that
proposed
method
can
accurately
with
improved
robustness.
ACS Applied Nano Materials,
Journal Year:
2024,
Volume and Issue:
7(15), P. 17151 - 17192
Published: July 24, 2024
The
advancement
of
precision
medicine
in
modern
biomedicine
has
been
significantly
propelled
by
the
emergence
micro/nanorobots.
combination
micro/nanorobots
and
offers
unique
advantages
holds
attractive
potential
for
applications.
It
effectively
addresses
challenges
encountered
traditional
robots
areas
such
as
driving,
sensing,
intelligence
other
aspects,
especially
application
cancer
cardiovascular
diseases,
which
is
a
hot
field
interdisciplinary
research
recent
years.
This
review
succinctly
delineates
analyzes
advancements
First,
achievements
years
are
systematically
classified
introduced
from
four
perspectives:
manufacturing
design,
drive
control,
biomedical
degradation.
In
particular,
in-depth
discussions
were
conducted
regarding
solutions
each
stage.
Second,
based
on
latest
results
applications,
development
direction
industrial
applications
key
technical
aspects
that
need
to
be
paid
attention
emphasized.
Finally,
we
discuss
opportunities
future,
it
expected
will
become
more
sophisticated
capable
performing
multiple
medical
functions
tasks.
They
implemented
vivo
assist
doctors
diagnosing
treating
diseases.
shows
significant
medicine.
Cyborg and Bionic Systems,
Journal Year:
2024,
Volume and Issue:
5
Published: Jan. 1, 2024
Magnetic
soft
robots
have
recently
become
a
promising
technology
that
has
been
applied
to
minimally
invasive
cardiovascular
surgery.
This
paper
presents
the
analytical
modeling
of
novel
multi-section
magnetic
robot
(MS-MSR)
with
multi-curvature
bending,
which
is
maneuvered
by
an
associated
collaborative
multirobot
navigation
system
(CMNS)
actuation
and
ultrasound
guidance
targeted
for
intravascular
intervention.
The
kinematic
dynamic
analysis
MS-MSR’s
telescopic
motion
performed
using
optimized
Cosserat
rod
model
considering
effect
external
heterogeneous
field,
generated
mobile
manipulator
adapt
complex
steering
scenarios.
Meanwhile,
extracorporeal
exploited
track
robot’s
distal
tip
realize
closed-loop
control.
We
also
conduct
quadratic
programming-based
optimization
scheme
synchronize
multi-objective
task-space
CMNS
null-space
projection.
It
allows
formulation
comprehensive
controller
priority
collaboration.
Experimental
results
demonstrate
proposed
can
be
successfully
navigated
within
multi-bifurcation
environment
shape
error
3.62±1.28∘1.080.45mm
under
through
in
vitro
ultrasound-guided
vasculature
interventional
tests.
Future Medicinal Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 16
Published: Jan. 30, 2025
Background:
Due
to
the
divers
biological
applications
of
Cu(II)
complexes,
we
in
this
study
reports
various
complexes.
The
aims
synthesize
and
assess
new
complexes
as
powerful
β-glucuronidase
inhibitors.
Methods:
Five
Schiff
base
ligands
their
were
synthesized,
characterized,
screened
against
inhibitory
activity.
Results:
In
series,
compounds
3e,
3c,
2b,
2c
ascribed
inhibition
ranging
from
(IC50
=
3.0
±
0.7
µM)
19.2
0.8
µM).
A
precise
particular
arrangement
atoms
is
suggested
by
triclinic
p-1
space
group
existence
a
single
molecule
an
asymmetric
unit,
which
are
indispensable
for
reactivity
well
stability
compounds.
analysis
Hirshfeld
surface
provides
information
about
hydrogen
intermolecular
π–π
interactions.
Based
on
molecular
docking,
binding
potency
increasing
complexation
3a-e
compared
2a-e
reference
Saccharic
acid
uronic
isofagomine
inhibitor,
suggesting
that
it
may
be
potent
inhibitor
these
receptors.
Conclusion:
work
recognizes
latent
active
novel
β-glucoronidase
inhibitors,
further
support
harnessed
development
drugs.
Mathematics,
Journal Year:
2025,
Volume and Issue:
13(3), P. 433 - 433
Published: Jan. 28, 2025
In
this
work,
it
is
taken
into
account
that
in
nature,
due
to
pressure
and
temperature,
water
drops
general
are
either
spherical
or
ellipsoidal.
Thus,
starting
from
a
more
structure,
3D
elliptical
surface
(oblate
spheroid)
constructed,
which,
by
means
of
parameters,
can
be
turned
shape.
Hexagons
built
on
rectangular
horizontal
plane,
then
plane
passed
through
an
at
height
h,
which
determined
parameter
θ.
As
result
the
cutting
these
surfaces,
curve
obtained,
both
ellipsoidal;
if
hexagons
within
perimeter
ellipse
obtained
as
function
θ,
they
marked
with
N,
outside
perimeter,
E.
Several
frozen
nucleation
centers
established,
same
layer
different
planes,
marking
them
F
their
first
eight
neighbors
B.
The
calculations
based
modified
snowflake
model
carried
out
tile
layer,
governed
thermodynamic
factors
α,
β,
γ,
leading
results
depend
position
nucleator,
symmetrical
asymmetrical
for
than
one
center
external
formed
vapor
functions
membrane.
