The Impact of the Physical Activity Level on Sarcopenic Obesity in Community-Dwelling Older Adults

Healthcare, Journal Year: 2024, Volume and Issue: 12(3), P. 349 - 349

Published: Jan. 30, 2024

Previous studies have reported that low levels of physical activity result in sarcopenic obesity (SO). However, the effects specific intensities on SO and optimal amount for lowering prevalence not been well studied. This study aimed to identify intensity related a lower SO. cross-sectional used data from nationwide Korean Frailty Aging Cohort Study (KFACS), which included 2071 older adults (1030 men, 1041 women). was defined according criteria European Society Clinical Nutrition Metabolism (ESPEN) Association Obesity (EASO). Multivariate logistic regression analysis performed investigate association between level The high group had significantly than non-high (low moderate activity) group. On other hand, moderate-intensity associated with A total energy expenditure > 3032 kcal/week (433 kcal/day) men 2730 (390 women reduced described above may be beneficial reducing

Language: Английский

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A Comprehensive Risk Factor Exploration: Korean Nationwide Cross-Sectional Study of Sarcopenia Obesity in Young-Old Males—Investigating the Prevalence, Somatometric, Biochemical, and Behavioral Traits

Healthcare, Journal Year: 2024, Volume and Issue: 12(6), P. 700 - 700

Published: March 21, 2024

Sarcopenic obesity refers to the coexistence of sarcopenia and obesity. This study assessed prevalence risk factors for sarcopenic in community-dwelling older males Korea. cross-sectional analyzed data from 1060 participants. The participants were screened examined various factors, composed somatometric, biochemical, behavioral traits, including age; height; weight; body mass index; waist circumference; skeletal muscle fasting glucose, triglycerides, cholesterol levels; systolic diastolic blood pressure; smoking drinking traits. men had a weighted value 9.09% (95% CI: 7.20–11.41). clinical included short height, as well high weight, index, circumference, triglyceride levels, pressure, pressure. Specific found among men. These findings may be beneficial primary care clinicians healthcare professionals identifying individuals with referring them early detection treatment.

Language: Английский

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Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation

International Immunopharmacology, Journal Year: 2022, Volume and Issue: 111, P. 109083 - 109083

Published: July 30, 2022

Overnutrition-induced hypothalamic inflammation greatly disturbs feeding behavior and energy homeostasis as well the pathogenesis of obesity. Butyrate, a short-chain fatty acid, reportedly participates in regulation immune response metabolism body. However, role butyrate overnutrition-induced microglial activation remains unclear. In present study, we established high-fat diet (HFD)-induced model mice. Oral supplementation with sodium (NaB) significantly reduced HFD-induced microgliosis, inflammatory cytokine expression, endoplasmic reticulum (ER) stress, neuronal apoptosis, neuropeptide Y (NPY) expression mouse hypothalamus. Utilizing high-glucose (HG)-stimulated vitro, found that NaB inhibited HG-induced factor IL-1β. Moreover, exerted an antioxidant effect by balancing HO-1 NOX4 thus preventing reactive oxygen species (ROS) production HG-treated microglia. Interestingly, treatment promoted process formation extension via Akt/Cdc42 pathway under both normal HG-stimulated conditions, indicating resting morphology Taken together, our study revealed for first time anti-inflammatory effects inflammation, which might become potential therapeutic option obesity prevention treatment.

Language: Английский

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Impact of overweight and obesity on the risk of hepatocellular carcinoma: a prospective cohort study in 14.3 million Koreans

British Journal of Cancer, Journal Year: 2022, Volume and Issue: 127(1), P. 109 - 115

Published: March 5, 2022

Language: Английский

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Weight loss and side-effects of liraglutide and lixisenatide in obesity and type 2 diabetes mellitus

Primary care diabetes, Journal Year: 2023, Volume and Issue: 17(5), P. 460 - 465

Published: Aug. 3, 2023

Language: Английский

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Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension

Diabetes & Metabolism Journal, Journal Year: 2022, Volume and Issue: 46(3), P. 355 - 376

Published: May 26, 2022

Carbohydrate-restricted diets and intermittent fasting (IF) have been rapidly gaining interest among the general population patients with cardiometabolic disease, such as overweight or obesity, diabetes, hypertension. However, there are limited expert recommendations for these dietary regimens. This study aimed to evaluate level of scientific evidence on benefits harms carbohydrate-restricted IF make responsible recommendations. A meta-analysis systematic literature review 66 articles 50 randomized controlled trials (RCTs) 10 eight RCTs was performed. Based analysis, following suggested. In adults a moderately-low carbohydrate low diet (mLCD) can be considered regimen weight reduction. type 2 diabetes mellitus, mLCD improving glycemic control reducing body weight. contrast, very-low (VLCD) recommended against in diabetes. Furthermore, no suggested VLCD Here, we describe results our analysis

Language: Английский

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Effect of carbohydrate-restricted diets and intermittent fasting on obesity, type 2 diabetes mellitus, and hypertension management: consensus statement of the Korean Society for the Study of obesity, Korean Diabetes Association, and Korean Society of Hypertension

Clinical Hypertension, Journal Year: 2022, Volume and Issue: 28(1)

Published: June 1, 2022

Carbohydrate-restricted diets and intermittent fasting (IF) have been rapidly gaining interest among the general population patients with cardiometabolic disease, such as overweight or obesity, diabetes, hypertension. However, there are limited expert recommendations for these dietary regimens. This study aimed to evaluate level of scientific evidence on benefits harms carbohydrate-restricted IF make responsible recommendations.

Language: Английский

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Metabolically Healthy Obesity: Epidemiology, Criteria, and Implications in Chronic Kidney Disease

Journal of Obesity & Metabolic Syndrome, Journal Year: 2022, Volume and Issue: 31(3), P. 208 - 216

Published: Sept. 19, 2022

The increasing prevalence of obesity is a worldwide health concern.Although primarily affects the development cardiometabolic disorders, it has also been closely linked to chronic kidney disease (CKD).However, potential causal relationships between and CKD remain unclear, as share number common risk factors.Accordingly, incident in obese people without metabolic abnormalities, called "metabolically healthy obesity" (MHO), matter interest.Recent investigations found that MHO was related increased CKD; however, conclusions were based on static state.According previous publications, approximately one-half initially identified became metabolically unhealthy, while one-tenth reduced their body weight normal range remaining healthy.It essential consider these transitions obese-metabolic status when analyzing obesity-related outcomes.This review discusses research patients with CKD.Furthermore, we summarize recent reports implications discuss possible mechanisms relationship CKD.

Language: Английский

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The Longitudinal Effect of Ultra‐Processed Food on the Development of Dyslipidemia/Obesity as Assessed by the NOVA System and Food Compass Score

Molecular Nutrition & Food Research, Journal Year: 2023, Volume and Issue: 67(20)

Published: Aug. 31, 2023

Ultra-processing food (UPF) has been a nutrition and health interest. This study is aimed to investigate the association between UPF consumption risk of obesity or dyslipidemia.This performed using an ongoing cohort including 17 310 individuals aged ≥40 years in South Korea. categorized by NOVA system FCS, respectively. After average 5-year follow-up, there positive NOVA-defined dyslipidemia. The Q4 group almost 20% higher than that Q1 (men, adjusted HR = 1.209 [95% CI 1.039-1.407], women, 1.195 1.096-1.303]). Consuming high-FCS foods (less processed healthier foods) show lower for dyslipidemia both sexes women compared low-FCS dyslipidemia, 0.857 0.744-0.988]; 0.919 0.850-0.993], obesity, 0.759 0.628-0.916]).Higher intakes assessed FCS are associated with increased incidences obesity. Furthermore, shows statistically significant negative AMED score, indicating poor diet quality.

Language: Английский

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Association of low muscle strength with metabolic dysfunction-associated fatty liver disease: A nationwide study

World Journal of Gastroenterology, Journal Year: 2023, Volume and Issue: 29(45), P. 5962 - 5973

Published: Dec. 1, 2023

There is limited evidence regarding the association between muscle strength and metabolic dysfunction-associated fatty liver disease (MAFLD).To investigate MAFLD in general population Korea.This nationwide representative cross-sectional study included 31649 individuals aged ≥ 19 years who participated Korea National Health Nutrition Examination Survey 2015 2018. Odds ratios (ORs) 95% confidence intervals (95%CIs) for according to sex-specific quartiles of strength, defined by relative handgrip were calculated using multivariable logistic regression analysis. Additionally, analysis was used assess probable fibrosis patients with MAFLD.Of all participants, 29.3% had MAFLD. The prevalence significantly higher lower quartile groups sexes, age (P < 0.001). A 1.92-fold (OR = 1.92, 95%CI: 1.70-2.16) 3.12-fold 3.12, 2.64-3.69) risk observed lowest (Q1) group than other (Q2-Q4) highest (Q4) group, respectively. ORs increased a dose-dependent manner trend These associations persisted both sexes. An inverse subgroups age, obesity, diabetes mellitus. In MAFLD, odds severe Q1 1.83, 1.25-2.69) (Q2-Q4).Among Korean adults, low associated an

Language: Английский

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