Research Progress of Osteoarthritis Treatment by Low Intensity Pulsed Ultrasound

Smart Medicine, Год журнала: 2025, Номер 4(2)

Опубликована: Май 16, 2025

With the intensification of global population aging, osteoarthritis (OA) has emerged as a major socioeconomic burden requiring urgent therapeutic interventions. Low-intensity pulsed ultrasound (LIPUS), non-invasive physical therapy modality, delivers acoustic energy to target tissues with negligible thermal effects. Accumulating evidence from preclinical studies and randomized controlled trials demonstrated its potential decelerate OA progression. This systematic review synthesizes current knowledge on LIPUS-mediated management, elucidates mechanistic pathways through biomechanical molecular analyses, strategies combining LIPUS biomaterials improve efficacy, evaluates clinical translation challenges, proposes standardized treatment protocols optimize outcomes.

Язык: Английский

P13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction

Biochemical Genetics, Год журнала: 2025, Номер unknown

Опубликована: Май 27, 2025

Язык: Английский