Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Май 13, 2025

Background and Aims: Pulmonary and/or peripheral venous congestion defines the clinical diagnosis of acute heart failure (HF). However, systolic pulmonary arterial pressure (sPAP) thresholds at which (chest X-ray) inferior vena cava (IVC) occur are not well established. This study aimed to identify a cut-off value sPAP that reliably indicates HF. Methods Results: We retrospectively included 380 consecutive patients hospitalized for HF an Italian referral center, excluding those with severe tricuspid regurgitation. Receiver operating characteristic (ROC) curve analysis Youden’s J statistic identified threshold ≥ 48.75 mmHg as most accurate in predicting both (sensitivity = 89.9%, specificity 73%) 88.3%, 82.5%) fluid overload. The association between this was confirmed by chi-square testing (p < 0.001) multivariate logistic regression 0.001). After adjustment confounders, independently associated all-cause death or hospitalization (HR 1.713; 95% CI 1.127–2.602; p 0.012). Conclusions: Acute decompensation is characterized least moderately elevated values.

Язык: Английский