Fabrication of β-TCP ceramic scaffold with hierarchical pore structure using 3D printing and porogen: Investigation of osteoinductive and bone defects repair properties

Applied Materials Today, Год журнала: 2024, Номер 40, С. 102351 - 102351

Опубликована: Июль 27, 2024

Язык: Английский

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Natural Loofah Sponge Inspired 3d Printed Bionic Scaffolds Promote Personalized Bone Defect Regeneration

Опубликована: Янв. 1, 2024

Язык: Английский

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Enzyme-delivery metal-organic framework composite coatings for restoration of hyperglycemia-damaged osteoblast differentiation

Biomaterials Advances, Год журнала: 2024, Номер 166, С. 214055 - 214055

Опубликована: Сен. 25, 2024

Язык: Английский

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Culturing 3D chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds in a dynamic environment enhances osteochondral reconstruction

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 283, С. 137892 - 137892

Опубликована: Ноя. 22, 2024

Язык: Английский

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3D Printing of Polyester Scaffolds for Bone Tissue Engineering: Advancements and Challenges

Advanced Materials Technologies, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 27, 2024

Abstract Polyesters have garnered significant attention in bone tissue engineering (BTE) due to their tunable degradation rates, biocompatibility, and convenient processing. This review focuses on recent advancements challenges the 3D printing of polyester‐based scaffolds for BTE. Various techniques, such as fused deposition modeling (FDM), selective laser sintering (SLS), vat photopolymerization (VP), Wet‐spun additive manufacturing, are explored, emphasizing ability construct with precise architectural control. The main printed polyester limited mechanical properties, lack inherent bioactivity, release acidic byproducts during biodegradation. Strategies enhance scaffold performance, incorporating bioactive ceramics growth factors, discussed, focusing improving osteoconductivity, osteoinductivity, strength. Recent studies integrating these components into techniques optimize porosity biodegradability presented. Finally, addresses ongoing issues, difficulty some biomolecules bioceramics improved clinical translation. comprehensive overview aims provide insight future directions potential solutions overcoming limitations 3D‐printed

Язык: Английский

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3D Printed Calcium Phosphate Physiochemically Dual-Regulating Pro-Osteogenesis and Antiosteolysis for Enhancing Bone Tissue Regeneration

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(28), С. 37007 - 37016

Опубликована: Июль 2, 2024

Osteoblasts and osteoclasts are two of the most important types cells in bone repair, their bone-forming bone-resorbing activities influence process repair. In this study, we proposed a physicochemical bidirectional regulation strategy via ration by physically utilizing hydroxyapatite nanopatterning to recruit induce MSCs osteogenic differentiation chemically inhibiting osteolysis activity through loaded zoledronate. The nanorod-like coating was fabricated modified hydrothermal while zoledronic acid chelation within calcium ions. fabrication hydroxyapatite/zoledronic composite biomaterial. This biomaterial promotes tissue regeneration vitro results tested on RAW 246.7 indicated that enhanced cells' physical sensing system, therefore enhancing osteogenesis. At same time inhibited downregulating RANK-related genes. research provides promising for contributes field orthopedic implants.

Язык: Английский

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