Abstract
Reactive
oxygen
species
play
a
crucial
role
in
cell
signaling
pathways
during
wound
healing
phases.
Treatment
strategies
to
balance
the
redox
level
deep
tissue
are
emerging
for
management.
In
recent
years,
reactive
scavenging
agents
including
natural
antioxidants,
(ROS)
nanozymes,
and
antioxidant
delivery
systems
have
been
widely
employed
inhibit
oxidative
stress
promote
skin
regeneration.
Here,
importance
of
different
phases
is
critically
analyzed.
Various
cutting‐edge
bioactive
ROS
nanoscavengers
platforms
discussed.
This
review
also
highlights
future
directions
therapies
via
scavenging.
comprehensive
offers
map
research
on
scavengers
with
balancing
mechanisms
action
process,
which
benefits
development
clinical
applications
next‐generation
scavenging‐based
nanomaterials
Journal of Nanobiotechnology,
Год журнала:
2023,
Номер
21(1)
Опубликована: Июль 24, 2023
Abstract
The
stimuli-responsive
nanofibers
prepared
by
electrospinning
have
become
an
ideal
material
due
to
their
large
specific
surface
area
and
porosity,
which
can
respond
extremely
quickly
external
environmental
incitement.
As
intelligent
drug
delivery
platform,
efficiently
load
drugs
then
be
stimulated
conditions
(light,
temperature,
magnetic
field,
ultrasound,
pH
or
ROS,
etc.)
achieve
slow,
on-demand
targeted
release,
showing
great
potential
in
areas
such
as
delivery,
tumor
therapy,
wound
dressing,
tissue
engineering.
Therefore,
this
paper
reviews
the
recent
trends
of
electrospun
platforms
field
biomedicine.
Biomaterials Science,
Год журнала:
2023,
Номер
11(9), С. 3051 - 3076
Опубликована: Янв. 1, 2023
This
review
offers
systematic
considerations
of
material
design
principles
and
fabrication
techniques
for
biomimetic
skin
tissue
engineering
scaffolds.
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(10)
Опубликована: Янв. 2, 2024
The
presence
of
bacteria
in
diabetic
wounds
not
only
leads
to
the
formation
biofilms
but
also
triggers
oxidative
stress
and
inflammatory
responses,
which
hinder
wound-healing
process.
Therefore,
it
is
imperative
formulate
a
comprehensive
strategy
that
can
proficiently
eliminate
enhance
wound
microenvironment.
Herein,
this
work
develops
multifunctional
metal-phenolic
nanozymes
(TA-Fe/Cu
nanocapsules),
wherein
one-pot
coordination
tannic
acid
(TA)and
Fe
Macromolecular Bioscience,
Год журнала:
2022,
Номер
23(2)
Опубликована: Ноя. 21, 2022
The
development
of
tissue
engineering
scaffolds
is
great
significance
for
the
repair
and
regeneration
damaged
tissues
organs.
Silk
fibroin
(SF)
a
natural
protein
polymer
with
good
biocompatibility,
biodegradability,
excellent
physical
mechanical
properties
processability,
making
it
an
ideal
universal
scaffold
material.
Nanofibers
prepared
by
electrospinning
have
attracted
extensive
attention
in
field
due
to
their
properties,
high
specific
surface
area,
similar
morphology
as
extracellular
matrix
(ECM).
combination
silk
promising
strategy
preparation
scaffolds.
In
this
review,
research
progress
electrospun
nanofibers
skin,
vascular,
bone,
neural,
tendons,
cardiac,
periodontal,
ocular
other
discussed
detail.
Journal of Energy Storage,
Год журнала:
2023,
Номер
68, С. 107660 - 107660
Опубликована: Май 17, 2023
This
study
aimed
to
introduce
a
smart
multifunctional
textile
composed
of
phase
change
material,
i.e.,
polyethylene
glycol
(PEG),
with
potential
for
thermo-regulative
biomedical
application.
PEG
was
efficiently
form-stabilized
polycaprolactone,
and
the
nanofibers
mats
were
developed
by
electrospinning
overcome
leakage
issue
during
process.
Gelatin
curcumin
also
incorporated
enable
performance
textiles.
The
results
revealed
that
electrospun
possessed
randomly
oriented
morphology,
sufficient
water
absorption
capability,
good
mechanical
properties,
excellent
performance.
fibers'
diameter
varied
from
220
nm
370
nm,
tensile
strength
ranging
10
30
MPa.
Furthermore,
fabricated
latent
heat
61.7
J/g
reliable
energy
absorption-release
cyclability
over
100
heating-cooling
cycles.
curcumin-loaded
textiles
an
initial
burst
release
followed
sustained
one
week.
They
further
presented
significant
antioxidant
activity
81.23.7
±
3.08
%
after
24
h,
introducing
great
application
as
dressing
diminish
inflammation
cooling
effect.
