The Journal of Antibiotics, Год журнала: 2020, Номер 73(8), С. 504 - 525
Опубликована: Июнь 8, 2020
Язык: Английский
Natural Product Reports, Год журнала: 2021, Номер 38(2), С. 362 - 413
Опубликована: Янв. 1, 2021
This review covers the literature published in 2019 for marine natural products (MNPs), with 719 citations (701 period January to December 2019) referring compounds isolated from microorganisms and phytoplankton, green, brown red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves other intertidal plants microorganisms. The emphasis is on new (1490 440 papers 2019), together relevant biological activities, source organisms country of origin. Pertinent reviews, biosynthetic studies, first syntheses, syntheses that led revision structures or stereochemistries, have been included. Methods used study fungi their chemical diversity also discussed.
Язык: Английский
Процитировано
300
Frontiers in Marine Science, Год журнала: 2021, Номер 8
Опубликована: Март 16, 2021
Coastal countries have traditionally relied on the existing marine resources (e.g., fishing, food, transport, recreation, and tourism) as well tried to support new economic endeavors (ocean energy, desalination for water supply, seabed mining). Modern societies lifestyle resulted in an increased demand dietary diversity, better health well-being, biomedicines, natural cosmeceuticals, environmental conservation, sustainable energy sources. These societal needs stimulated interest of researchers diverse underexplored environments promising sources biomolecules biomass, they are addressed by emerging field (blue) biotechnology. Blue biotechnology provides opportunities a wide range initiatives commercial pharmaceutical, biomedical, cosmetic, nutraceutical, feed, agricultural, related industries. This article synthesizes essence, opportunities, responsibilities, challenges encountered outlines attainment valorization directly derived or bio-inspired products from organisms. First, concept bioeconomy is introduced. Then, diversity bioresources including overview most prominent organisms their potential biotechnological uses described. followed introducing methodologies exploration these main use case scenarios food agronomy, bioremediation climate change, materials, healthcare, well-being sectors. The key aspects fields legislation funding provided, with emphasis importance communication stakeholder engagement at all levels development. Finally, vital overarching concepts, such quadruple helix Responsible Research Innovation principle highlighted important follow within field. authors this review collaborating under European Commission-funded Cooperation Science Technology (COST) Action Ocean4Biotech – transdisciplinary networking platform focus study state affairs.
Язык: Английский
Процитировано
147
Natural Product Reports, Год журнала: 2021, Номер 39(3), С. 560 - 595
Опубликована: Окт. 9, 2021
The mangrove forests are a complex ecosystem occurring at tropical and subtropical intertidal estuarine zones nourish variety of fungi that produce 1387 secondary metabolites with the feature source, chemical bioactive diversity.
Язык: Английский
Процитировано
127
Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products, Год журнала: 2023, Номер unknown, С. 1 - 546
Опубликована: Янв. 1, 2023
Язык: Английский
Процитировано
50
Food Production Processing and Nutrition, Год журнала: 2023, Номер 5(1)
Опубликована: Март 20, 2023
Green seaweed, as the most abundant species of macroseaweeds, is an important marine biological resource. It a rich source several amino acids, fatty and dietary fibers, well polysaccharides, polyphenols, pigments, other active substances, which have crucial roles in various processes such antioxidant activity, immunoregulation, anti-inflammatory response. In recent years, attention to resources has accelerated exploration utilization green seaweeds for greater economic value. This paper elaborates on main nutrients substances present different provides review their activities applications high-value utilization.
Язык: Английский
Процитировано
49
Bioresource Technology, Год журнала: 2021, Номер 329, С. 124895 - 124895
Опубликована: Фев. 27, 2021
Язык: Английский
Процитировано
105
Marine Life Science & Technology, Год журнала: 2021, Номер 3(4), С. 488 - 518
Опубликована: Май 19, 2021
Abstract Natural products derived from marine microorganisms have received great attention as a potential resource of new compound entities for drug discovery. The unique environment brings us large group sulfur-containing natural with abundant biological functionality including antitumor, antibiotic, anti-inflammatory and antiviral activities. We reviewed all the 484 (non-sulfated) isolated microorganisms, which 59.9% are thioethers, 29.8% thiazole/thiazoline-containing compounds 10.3% sulfoxides, sulfones, thioesters many others. A selection 133 was further discussed on their structure–activity relationships, mechanisms action, biosynthesis, druggability. This is first systematic review conducted January 1987, when one reported, to December 2020.
Язык: Английский
Процитировано
95
Organic Chemistry Frontiers, Год журнала: 2021, Номер 8(9), С. 2019 - 2058
Опубликована: Янв. 1, 2021
In this review, we focus in all aspects of NMR simulation natural products, from the fundamentals to new computational toolboxes available, combining advanced quantum chemical calculations with upstream data processing and machine learning.
Язык: Английский
Процитировано
81
Natural Product Reports, Год журнала: 2020, Номер 38(7), С. 1235 - 1242
Опубликована: Дек. 9, 2020
Marine natural products depend on a long research pipeline, starting with taxonomy; to avoid future global crises we must invest in discovery-driven prepare novel solutions unimagined problems.
Язык: Английский
Процитировано
72
Natural Product Reports, Год журнала: 2021, Номер 38(12), С. 2145 - 2153
Опубликована: Янв. 1, 2021
The recent achievements in the transfer of biosynthetic pathways plant natural products heterologous organisms offer new perspectives towards supply these compounds through metabolic engineering approaches.
Язык: Английский
Процитировано
72