A novel and versatile cough simulator for respiratory disease studies DOI Creative Commons

Zackary Van Zante,

Tanya Purwar,

Soohyeon Kang

и другие.

Physics of Fluids, Год журнала: 2024, Номер 36(12)

Опубликована: Дек. 1, 2024

The COVID-19 pandemic has highlighted the critical need for comprehensive studies on respiratory diseases, particularly those focusing human coughs as a primary mode of transmission. Traditional experimental methods studying cough dynamics often fall short in replicating complexity coughs, limiting our understanding virus This study introduces novel and versatile simulator capable wide range jet profiles with high accuracy repeatability. device employs synthetic actuator driven by signals derived from parameters, paired an aerosol chamber interchangeable mouthpieces. was characterized using particle image velocimetry flow visualization techniques, demonstrating its ability to generate jets peak velocities ranging approximately 3–39 m/s velocity times 8.75 60.00 ms. simulated exhibit characteristic starting-jet interrupted-jet stages observed coughs. Calibration maps were developed allow precise tuning enhancing device's versatility. simulator's reproducibility validated through repeated trials, showing consistent characteristics despite turbulent nature jets. pulsatile provides reliable adaptable platform cough-generated aerosols, contributing better disease transmission development effective mitigation strategies.

Язык: Английский

Impinging jet ventilation: Mitigating influenza transmission through partition and exhaust layout optimization DOI Open Access
Puyang Zhang, Xinchao Su, Jane W. Z. Lu

и другие.

Physics of Fluids, Год журнала: 2025, Номер 37(1)

Опубликована: Янв. 1, 2025

This paper investigates the transmission characteristics of cough droplets from infected individuals in office environments under influence an impinging jet ventilation (IJV) system based on Eulerian–Lagrangian model. The accuracy dispersed phase model and IJV simulation was validated by analyzing a single droplet evaporation model, publicly available experimental results, previously simulated results. effects different exhaust locations, relative positioning to individual, application partitions spatial propagation are explored. results indicate that exhibit significant ability obstruct capture droplets. Under static conditions, they capable capturing over 36% generated coughing, although this efficiency may be slightly influenced system. notably affects movement, with progressively converging toward upper-left corner room as airflow develops. exhausts, combination system, is crucial impeding removing Taking into account variations individual's position, centrally located arrangement might provide more effective inhibition virus dispersion.

Язык: Английский

Процитировано

2

Infectious cough droplet dynamics in a makeshift hospital isolation ward DOI
Leslie Kojo Norvihoho, Yi Liu, Jing Yin

и другие.

Physics of Fluids, Год журнала: 2025, Номер 37(2)

Опубликована: Фев. 1, 2025

The COVID-19 pandemic highlighted the need for rapidly deployable healthcare facilities, leading to increased use of modular construction methods. Nonetheless, knowledge about airflow patterns and spread bioaerosols in these wards remains insufficient, potentially heightening risk cross-infection among workers patients. This paper presents a ventilation design negative-pressure ward aimed at reducing infectious particles. We investigate effects various designs, patient postures (sitting supine), air changes per hour (ACH) on cough droplets an airborne infection isolation room using large eddy simulation Eulerian–Lagrangian model. Findings show that ceiling exhaust grilles (design 2) resulted lowest radial dispersion (3.64 m) 12 ACH, while sidewall exhausts (baseline) performed best higher ACH levels. Seated patients had quicker droplet evaporation compared those supine position. setups survival included bed's bottom ceiling, maintaining minimum ACH. Cases 5 13, with over patient's head bottom, showed concentrations DPM, under 0.008 km−3 near source less than 0.001 mid-room. Sitting posture consistently led lower DPM concentrations. research emphasizes critical role placement re-circulation transmission risks, ultimately contributing improved strategies control AII rooms.

Язык: Английский

Процитировано

0

The effects of ventilation layout on cough droplet dynamics relating to seasonal influenza DOI
Leslie Kojo Norvihoho, Jing Yin,

Xin-Gang Zhu

и другие.

Physics of Fluids, Год журнала: 2024, Номер 36(11)

Опубликована: Ноя. 1, 2024

The primary aim of this paper is to investigate airborne virus transmission in a typical meeting room relating the heating, ventilation, and air conditioning (A.C.) systems. While installation 4-way cassette A.C. systems offices rooms has become increasingly common, their efficiency mitigating short-range spread remains poorly understood. Addressing gap critical post-pandemic era, where understanding limitations various ventilation paramount for public health. We systematically compare performance A.C., configurations mixing displacement systems, natural controlling respiratory viruses. Our research uniquely integrates evaporation models accurately simulate cough clouds' multiphase behavior under both quiescent thermally influenced conditions. study benchmarks these against two widely recognized standards (i.e., 5 changes per hour 10 l/s person), offering evidence-based insights applicable across diverse indoor settings. findings reveal significant thermal effects case, resulting 32.3%, 54.3%, 8.0% axial, vertical, lateral virus-laden droplets, respectively. Notably, 0.5 m/s system demonstrated superior performance, reducing axial by 29.6% compared other mechanical configurations. Furthermore, role exhaust outlets or doors was found be shaping pattern scenarios. This work can offer practical guidance office workers, engineers, health officials on enhancing infection control.

Язык: Английский

Процитировано

1

Numerical simulation of high-concentration droplet flow in an idealized mouth–throat airway model in the influence of environmental temperature and humidity DOI
Yu Liu, Xiaole Chen,

Jun Xie

и другие.

Physics of Fluids, Год журнала: 2024, Номер 36(12)

Опубликована: Дек. 1, 2024

The exchange of water vapor between high-concentration droplets and air significantly influences droplet deposition in the upper airway model during nebulizer use. This study employed a two-way coupled Eulerian–Lagrange method to quantify nebulized evaporation relative humidity (RH) variations within an idealized mouth–throat (MT) model, utilizing validated numerical models. interaction inhaled was computed using multiplier based on particle parcel method. Simulations normal saline flow inhalation MT were conducted under two environmental conditions: indoor (26.5 °C, RH = 50%) warm wet (30 75%), with various rates mirroring previous experiments. Droplet fractions (DFs) patterns recorded. results indicated that DF initially decreased then increased rising rates. largest discrepancy predicted measured DFs 10.86%. These findings support theory balance elevated dictates airway. Additionally, simulations revealed conditions affect DF, up 20.78%. hotspot shifted from anterior posterior pharynx.

Язык: Английский

Процитировано

1

Gravitational Interactions of Two Small Evaporating Drops DOI Creative Commons
Michael Rother

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Фев. 22, 2024

Abstract Relative trajectories are determined for a pair of water drops falling in air with radii between 2 μm and 30 μm. The droplets small enough that diffusion dominates convection evaporation, but significant drop inertia at low Reynolds number is considered. In addition to hydrodynamic lubrication forces, attractive van der Waals forces Maxwell slip taken into account. Because the loss mass not uniform due presence second drop, transfer momentum effectively decoupled, droplet position needs be assessed. Three outcomes compared. isolated result both employed as base case, since constant over each surface. Alternatively, bispherical coordinate solution two evaporating applied, positions 1) fixed by hydrodynamics or 2) allowed move based on nonspherical loss. all three cases, evaporation leads weaker inertial effects stronger effects. single sphere model has largest gap, followed solutions movable center, respectively. Critical horizontal offsets coalescence also calculated finite vertical offset. With molecular slip, approaches lead similar results, making choice method nearly inconsequential. Moderate agreement previous experiments an approximate, generalized form current theory obtained rate drops.

Язык: Английский

Процитировано

0

Gravitational Interactions of Two Small Evaporating Drops DOI
Michael Rother

Aerosol Science and Engineering, Год журнала: 2024, Номер 9(1), С. 52 - 66

Опубликована: Июль 16, 2024

Язык: Английский

Процитировано

0

A novel and versatile cough simulator for respiratory disease studies DOI Creative Commons

Zackary Van Zante,

Tanya Purwar,

Soohyeon Kang

и другие.

Physics of Fluids, Год журнала: 2024, Номер 36(12)

Опубликована: Дек. 1, 2024

The COVID-19 pandemic has highlighted the critical need for comprehensive studies on respiratory diseases, particularly those focusing human coughs as a primary mode of transmission. Traditional experimental methods studying cough dynamics often fall short in replicating complexity coughs, limiting our understanding virus This study introduces novel and versatile simulator capable wide range jet profiles with high accuracy repeatability. device employs synthetic actuator driven by signals derived from parameters, paired an aerosol chamber interchangeable mouthpieces. was characterized using particle image velocimetry flow visualization techniques, demonstrating its ability to generate jets peak velocities ranging approximately 3–39 m/s velocity times 8.75 60.00 ms. simulated exhibit characteristic starting-jet interrupted-jet stages observed coughs. Calibration maps were developed allow precise tuning enhancing device's versatility. simulator's reproducibility validated through repeated trials, showing consistent characteristics despite turbulent nature jets. pulsatile provides reliable adaptable platform cough-generated aerosols, contributing better disease transmission development effective mitigation strategies.

Язык: Английский

Процитировано

0