International Journal of Environmental Research and Public Health,
Год журнала:
2020,
Номер
17(15), С. 5467 - 5467
Опубликована: Июль 29, 2020
It
is
established
that
inflammation
involved
in
the
pathogenesis
of
Type
2
Diabetes
Mellitus
(T2DM)
by
promoting
insulin
resistance
and
impaired
beta
cell
function
pancreas.
Among
hypothesized
independent
risk
factors
implicated
pathogenetic
basis
disease,
periodontal
infection
has
been
proposed
to
promote
an
amplification
magnitude
advanced
glycation
end
product
(AGE)-mediated
upregulation
cytokine
synthesis
secretion.
These
findings
suggest
interrelationship
between
disease
type
diabetes,
describing
poor
metabolic
control
subjects
with
periodontitis
as
compared
nondiabetic
more
severe
T2DM
a
healthy
population,
significant
positive
correlation
inflammatory
parameters
glycated
hemoglobin
level.
Results
from
clinical
trials
show
treatment
able
improve
glycemic
diabetes.
Many
therapeutic
strategies
have
developed
conditions
conjunction
conventional
treatment,
among
which
ozone
(O3)
specific
concern.
The
principal
aim
this
trial
was
compare
effectiveness
intensive
intervention
consisting
gas
therapy
reducing
level
diabetic
patients
standard
treatment.This
study
12-month
unmasked
randomized
included
100
aged
40-74
years
older,
diabetes
mellitus
diagnosed.
All
received
or
randomly
assigned
order
(1:1).
primary
outcome
measure
at
3,
6,
9
12
months
randomization.
Secondary
outcomes
were
changes
parameters.At
months,
did
not
differences
than
decreasing
(HbA1C)
lack
balance
evident.Although
change
significant,
gaseous
tended
reduce
levels
hemoglobin.
shows
benefit
traditional
treatment.
Journal Of Clinical Periodontology,
Год журнала:
2018,
Номер
45(S20)
Опубликована: Июнь 1, 2018
Abstract
A
classification
scheme
for
periodontal
and
peri‐implant
diseases
conditions
is
necessary
clinicians
to
properly
diagnose
treat
patients
as
well
scientists
investigate
etiology,
pathogenesis,
natural
history,
treatment
of
the
conditions.
This
paper
summarizes
proceedings
World
Workshop
on
Classification
Periodontal
Peri‐implant
Diseases
Conditions.
The
workshop
was
co‐sponsored
by
American
Academy
Periodontology
(AAP)
European
Federation
(EFP)
included
expert
participants
from
all
over
world.
Planning
conference,
which
held
in
Chicago
November
9
11,
2017,
began
early
2015.
An
organizing
committee
AAP
EFP
commissioned
19
review
papers
four
consensus
reports
covering
relevant
areas
periodontology
implant
dentistry.
authors
were
charged
with
updating
1999
developing
a
similar
Reviewers
workgroups
also
asked
establish
pertinent
case
definitions
provide
diagnostic
criteria
aid
use
new
classification.
All
findings
recommendations
agreed
consensus.
introductory
presents
an
overview
conditions,
along
condensed
each
workgroup
sections,
but
readers
are
directed
thorough
discussion
rationale,
criteria,
interpretation
proposed
Changes
highlighted
discussed.
Although
intent
base
strongest
available
scientific
evidence,
lower
level
evidence
opinion
inevitably
used
whenever
sufficient
research
data
unavailable.
scope
this
align
update
current
understanding
schematic
tables
briefly
highlights
changes
made
It
cannot
present
wealth
information
reviews,
definition
papers,
that
has
guided
development
classification,
reference
its
either
management
or
investigation.
Therefore,
it
strongly
recommended
reader
introduction
these
subjects.
Accessing
publication
online
will
allow
links
view
source
(Table
).
Journal Of Clinical Periodontology,
Год журнала:
2018,
Номер
45(S20)
Опубликована: Июнь 1, 2018
Abstract
A
new
periodontitis
classification
scheme
has
been
adopted,
in
which
forms
of
the
disease
previously
recognized
as
“chronic”
or
“aggressive”
are
now
grouped
under
a
single
category
(“periodontitis”)
and
further
characterized
based
on
multi‐dimensional
staging
grading
system.
S
taging
is
largely
dependent
upon
severity
at
presentation
well
complexity
management,
while
provides
supplemental
information
about
biological
features
including
history‐based
analysis
rate
progression;
assessment
risk
for
possible
poor
outcomes
treatment;
that
its
treatment
may
negatively
affect
general
health
patient.
Necrotizing
periodontal
diseases,
whose
characteristic
clinical
phenotype
includes
typical
(papilla
necrosis,
bleeding,
pain)
associated
with
host
immune
response
impairments,
remain
distinct
category.
Endodontic‐periodontal
lesions,
defined
by
pathological
communication
between
pulpal
tissues
given
tooth,
occur
either
an
acute
chronic
form,
classified
according
to
signs
symptoms
have
direct
impact
their
prognosis
treatment.
Periodontal
abscesses
lesions
localized
accumulation
pus
within
gingival
wall
pocket/sulcus,
rapid
tissue
destruction
systemic
dissemination.
Journal Of Clinical Periodontology,
Год журнала:
2018,
Номер
45(S20)
Опубликована: Июнь 1, 2018
Abstract
Background
Authors
were
assigned
the
task
to
develop
case
definitions
for
periodontitis
in
context
of
2017
World
Workshop
on
Classification
Periodontal
and
Peri‐Implant
Diseases
Conditions.
The
aim
this
manuscript
is
review
evidence
rationale
a
revision
current
classification,
provide
framework
definition
that
fully
implicates
state‐of‐the‐art
knowledge
can
be
adapted
as
new
emerges,
suggest
system
implemented
clinical
practice,
research
epidemiologic
surveillance.
Methods
Evidence
gathered
four
commissioned
reviews
was
analyzed
interpreted
with
special
emphasis
changes
regards
understanding
available
prior
1999
classification.
systems
employed
variety
chronic
diseases
identified
key
criteria
classification/case
periodontitis.
Results
discusses
merits
based
Staging
Grading
proposes
framework.
Stage
I
IV
defined
severity
(primarily
periodontal
breakdown
reference
root
length
periodontitis‐associated
tooth
loss),
complexity
management
(pocket
depth,
infrabony
defects,
furcation
involvement,
hypermobility,
masticatory
dysfunction)
additionally
described
extent
(localized
or
generalized).
Grade
estimated
direct
indirect
progression
rate
three
categories:
slow,
moderate
rapid
(Grade
A‐C).
Risk
factor
analysis
used
grade
modifier.
Conclusions
paper
describes
simple
matrix
stage
appropriately
define
an
individual
patient.
proposed
extends
beyond
description
include
characterization
biological
features
disease
represents
first
step
towards
adoption
precision
medicine
concepts
It
also
provides
necessary
introduction
biomarkers
diagnosis
prognosis.
Journal Of Clinical Periodontology,
Год журнала:
2018,
Номер
45(S20)
Опубликована: Июнь 1, 2018
Abstract
Background
A
variety
of
systemic
diseases
and
conditions
can
affect
the
course
periodontitis
or
have
a
negative
impact
on
periodontal
attachment
apparatus.
Gingival
recessions
are
highly
prevalent
often
associated
with
hypersensitivity,
development
caries
non‐carious
cervical
lesions
exposed
root
surface
impaired
esthetics.
Occlusal
forces
result
in
injury
teeth
Several
developmental
acquired
prostheses
may
predispose
to
periodontium.
The
aim
this
working
group
was
review
update
1999
classification
regard
these
conditions,
develop
case
definitions
diagnostic
considerations.
Methods
Discussions
were
informed
by
four
reviews
1)
manifestions
conditions;
2)
mucogingival
around
natural
teeth;
3)
traumatic
occlusal
trauma;
4)
dental
tooth
related
factors.
This
consensus
report
is
based
results
expert
opinion
participants.
Results
Key
findings
included
following:
there
mainly
rare
(such
as
Papillon‐Lefevre
Syndrome,
leucocyte
adhesion
deficiency,
others)
major
effect
more
common
diabetes
mellitus)
variable
effects,
well
affecting
apparatus
independently
plaque
biofilm‐induced
inflammation
neoplastic
diseases);
diabetes‐associated
should
not
be
regarded
distinct
diagnosis,
but
recognized
an
important
modifying
factor
clinical
diagnosis
descriptor;
likewise,
tobacco
smoking
–
now
considered
dependence
nicotine
chronic
relapsing
medical
disorder
adverse
effects
supporting
tissues
modifier
importance
gingival
phenotype,
encompassing
thickness
width
context
novel
for
introduced;
5)
no
evidence
that
lead
loss,
lesions,
recessions;
6)
adaptive
mobility
normal
support,
whereas
they
progressive
reduced
usually
requiring
splinting;
7)
term
biologic
replaced
supracrestal
tissue
consisting
junctional
epithelium
connective
tissue;
8)
infringement
restorative
margins
within
and/or
loss
tissue.
However,
it
evident
whether
periodontium
caused
biofilm,
trauma,
toxicity
materials
combination
factors;
9)
anatomical
factors
tissues.
Conclusion
An
updated
manifestations
apparatus,
introduced.
Case
considerations
also
presented.
Periodontology 2000,
Год журнала:
2020,
Номер
83(1), С. 125 - 153
Опубликована: Май 8, 2020
Abstract
Periodontitis
is
a
multifactorial
chronic
inflammatory
disease
associated
with
dysbiotic
plaque
biofilms
and
characterized
by
progressive
destruction
of
the
tooth‐supporting
apparatus.
Globally,
it
estimated
that
740
million
people
are
affected
its
severe
form.
has
been
suggested
to
be
linked
obesity
metabolic
syndrome.
Obesity,
defined
as
excessive
fat
accumulation,
complex
disease,
high
increasing
prevalence.
Metabolic
syndrome
cluster
obesity,
dyslipidemia,
hypertension,
dysglycemia.
periodontitis
among
most
common
non‐communicable
diseases
large
body
evidence
from
epidemiologic
studies
supports
association
between
these
conditions.
Extensive
research
established
plausible
mechanisms
explain
how
conditions
can
negatively
impact
each
other,
pointing
bidirectional
adverse
relationship.
At
present
there
only
limited
available
few
intervention
studies.
Nevertheless,
global
burden
combined
epidemic
important
clinical
public
health
implications
for
dental
team.
In
accordance
risk
factor
approach
tackling
diseases,
proposed
oral
healthcare
professionals
have
an
role
in
promotion
periodontal
general
well‐being
through
facilitation
healthy
lifestyle
behaviours.
Journal Of Clinical Periodontology,
Год журнала:
2019,
Номер
46(4), С. 398 - 405
Опубликована: Март 19, 2019
Implementation
of
the
new
classification
periodontal
diseases
requires
careful
navigation
case
definitions
and
organization
diagnostic
process
along
rationale
easily
applicable
algorithms.
The
aim
this
report
was
to
describe
for
one
such
approach
designed
clinical
practice
education.The
authors
developed
empiric
decision-making
algorithms
based
on
effectively
discriminate
between
key
diagnoses
health,
gingivitis
periodontitis.A
stepwise
is
proposed
that
includes
(a)
a
sensitive
screening
step
able
suspect
periodontitis;
(b)
specific
confirmation
provide
differential
diagnosis
periodontitis
other
conditions
characterized
by
attachment
loss;
(c)
assess
severity
complexity
management
(staging);
(d)
risk
profile
(grading).
Specific
are
described
all
steps
process.The
allows
discrimination
different
health
disease.
accuracy
cost-effectiveness
need
be
validated
in
prospective
trials
generalizable
operators
with
level
expertise,
populations
settings.
Nutrients,
Год журнала:
2020,
Номер
12(5), С. 1471 - 1471
Опубликована: Май 19, 2020
Vitamin
D
(VD)
levels
have
been
gaining
growing
attention
in
Oral
Health.
During
growth
and
adulthood,
VD
deficiency
(VDD)
is
associated
with
a
wide
variety
of
oral
health
disorders,
impaired
synthesis
may
expedite
some
these
conditions.
In
children,
severe
VDD
can
induce
defective
tooth
mineralization,
resulting
dentin
enamel
defects.
As
consequence,
defects
increase
the
risk
onset
progression
dental
caries.
Further,
has
higher
prevalence
periodontitis
gingival
inflammation,
several
recent
preclinical
clinical
studies
unveiled
potential
pathways
through
which
interact
periodontium.
correction
supplementation
contribute
to
successful
treatment
periodontitis;
however,
alveolar
bone
regeneration
procedures
performed
baseline
patients
seem
more
prone
failure.
also
be
linked
pathology
entities
such
as
certain
cancers
events
osteonecrosis
jaw.
This
review
aims
provide
comprehensive
evidence
how
should
considered
promote
good
health,
summarize
hamper
development
its
role
Microorganisms,
Год журнала:
2023,
Номер
11(5), С. 1269 - 1269
Опубликована: Май 11, 2023
Periodontal
diseases
and
dental
caries
are
the
most
common
infectious
oral
impacting
health
globally.
Oral
cavity
is
crucial
for
enhancing
life
quality
since
it
serves
as
entranceway
to
general
health.
The
microbiome
strongly
correlated.
Gram-negative
anaerobic
bacteria
have
been
associated
with
periodontal
diseases.
Due
shortcomings
of
several
antimicrobial
medications
frequently
applied
in
dentistry,
lack
resources
developing
countries,
prevalence
inflammatory
conditions,
rise
bacterial
antibiotic
resistance,
there
a
need
reliable,
efficient,
affordable
alternative
solutions
prevention
treatment
Several
accessible
chemical
agents
can
alter
microbiota,
although
these
substances
also
unfavorable
symptoms
such
vomiting,
diarrhea,
tooth
discoloration.
Natural
phytochemicals
generated
from
plants
that
historically
used
medicines
categorized
prospective
alternatives
due
ongoing
quest
substitute
products.
This
review
concentrated
on
or
herbal
extracts
impact
by
decreasing
formation
biofilms
plaques,
preventing
proliferation
pathogens,
inhibiting
adhesion
surfaces.
Investigations
examining
effectiveness
safety
plant-based
presented,
including
those
conducted
over
past
decade.
Periodontology 2000,
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 14, 2023
Abstract
Periodontal
diseases
include
pathological
conditions
elicited
by
the
presence
of
bacterial
biofilms
leading
to
a
host
response.
In
diagnostic
process,
clinical
signs
such
as
bleeding
on
probing,
development
periodontal
pockets
and
gingival
recessions,
furcation
involvement
radiographic
bone
loss
should
be
assessed
prior
therapy,
following
active
during
long‐term
supportive
care.
addition,
patient‐reported
outcomes
increased
tooth
mobility,
migration,
tilting
also
considered.
More
important
patient,
however,
is
fact
that
assessment
must
followed
an
appropriate
treatment
plan.
Furthermore,
it
realized
diagnosis
based
which
may
not
reflect
disease
but
rather
represent
sequelae
previous
challenge.
Hence,
aim
present
review
provide
summary
criteria
required
classify
patients
with
health
or
disease.
Journal Of Clinical Periodontology,
Год журнала:
2018,
Номер
45(S20)
Опубликована: Июнь 1, 2018
Abstract
While
plaque‐induced
gingivitis
is
one
of
the
most
common
human
inflammatory
diseases,
several
non–plaque‐induced
gingival
diseases
are
less
but
often
major
significance
for
patients.
The
lesions
manifestations
systemic
conditions,
they
may
also
represent
pathologic
changes
limited
to
tissues.
A
classification
proposed,
based
on
etiology
and
includes:
Genetic/Developmental
disorders;
Specific
infections;
Inflammatory
immune
conditions
lesions;
Reactive
processes;
Neoplasms;
Endocrine,
Nutritional
metabolic
diseases;
Traumatic
Gingival
pigmentation.