EEG during dynamic facial emotion processing reveals neural activity patterns associated with autistic traits in children
Cerebral Cortex,
Год журнала:
2025,
Номер
35(2)
Опубликована: Янв. 22, 2025
Altered
brain
connectivity
and
atypical
neural
oscillations
have
been
observed
in
autism,
yet
their
relationship
with
autistic
traits
nonclinical
populations
remains
underexplored.
Here,
we
employ
electroencephalography
to
examine
functional
connectivity,
oscillatory
power,
broadband
aperiodic
activity
during
a
dynamic
facial
emotion
processing
task
101
typically
developing
children
aged
4
12
years.
We
investigate
associations
between
these
electrophysiological
measures
of
dynamics
as
assessed
by
the
Social
Responsiveness
Scale,
2nd
Edition
(SRS-2).
Our
results
revealed
that
increased
processing-related
across
theta
(4
7
Hz)
beta
(13
30
frequencies
correlated
positively
higher
SRS-2
scores,
predominantly
right-lateralized
(theta)
bilateral
(beta)
cortical
networks.
Additionally,
steeper
1/f-like
slope
(spectral
exponent)
fronto-central
electrodes
was
associated
scores.
Greater
aperiodic-adjusted
alpha
power
further
both
scores
slopes.
These
findings
underscore
important
links
children.
Future
work
could
extend
assess
electroencephalography-derived
markers
potential
mechanisms
underlying
behavioral
difficulties
autism.
Язык: Английский
Behavioural stochastic resonance across the lifespan
Cognitive Affective & Behavioral Neuroscience,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Abstract
Stochastic
resonance
(SR)
is
the
phenomenon
wherein
introduction
of
a
suitable
level
noise
enhances
detection
subthreshold
signals
in
non
linear
systems.
It
manifests
across
various
physical
and
biological
systems,
including
human
brain.
Psychophysical
experiments
have
confirmed
behavioural
impact
stochastic
on
auditory,
somatic,
visual
perception.
Aging
renders
brain
more
susceptible
to
noise,
possibly
causing
differences
SR
between
young
elderly
individuals.
This
study
investigates
motion
accuracy
throughout
lifespan,
with
214
participants
ranging
age
from
18
82.
Our
objective
was
determine
optimal
induce
an
SR-like
response
both
old
populations.
Consistent
existing
literature,
our
findings
reveal
diminishing
advantage
age,
indicating
that
efficacy
addition
progressively
diminishes.
Additionally,
as
individuals
peak
performance
achieved
lower
levels
noise.
provides
first
insight
into
how
changes
lifespan
healthy
adults
establishes
foundation
for
understanding
pathological
alterations
perceptual
processes
associated
aging.
Язык: Английский
EEG During Dynamic Facial Emotion Processing Reveals Neural Activity Patterns Associated with Autistic Traits in Children
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 28, 2024
Abstract
Altered
brain
connectivity
and
atypical
neural
oscillations
have
been
observed
in
autism,
yet
their
relationship
with
autistic
traits
non-clinical
populations
remains
underexplored.
Here,
we
employ
electroencephalography
(EEG)
to
examine
functional
connectivity,
oscillatory
power,
broadband
aperiodic
activity
during
a
dynamic
facial
emotion
processing
(FEP)
task
101
typically
developing
children
aged
4-12
years.
We
investigate
associations
between
these
electrophysiological
measures
of
dynamics
as
assessed
by
the
Social
Responsiveness
Scale,
2nd
Edition
(SRS-2).
Our
results
revealed
that
increased
FEP-related
across
theta
(4-7
Hz)
beta
(13-30
frequencies
correlated
positively
higher
SRS-2
scores,
predominantly
right-lateralized
(theta)
bilateral
(beta)
cortical
networks.
Additionally,
steeper
1/
f
-like
slope
(spectral
exponent)
fronto-central
electrodes
was
associated
scores.
Greater
aperiodic-adjusted
alpha
power
further
both
scores
slopes.
These
findings
underscore
important
links
children.
Future
work
could
extend
assess
EEG-derived
markers
potential
mechanisms
underlying
behavioural
difficulties
autism.
Язык: Английский
Testing retrogenesis and physiological explanations for tract-wise white matter aging: links to developmental order, fibre calibre, and vascularization
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 22, 2024
To
understand
the
consistently
observed
spatial
distribution
of
white-matter
(WM)
aging,
developmentally
driven
theories
termed
"retrogenesis"
have
gained
traction,
positing
that
order
WM
tract
development
predicts
declines.
Regions
develop
first
are
expected
to
deteriorate
last,
i.e.
"last-in-first-out".
Alternatively,
regions
which
most
rapidly
may
also
decline
in
or
"gains-predict-loss".
The
validity
such
remains
uncertain,
part
due
lack
clarity
on
definition
developmental
order.
Importantly,
our
recent
findings
suggest
aging
is
associated
with
physiological
parameters
as
perfusion,
be
linked
fibre
metabolic
need,
turn
varies
size.
Here
we
address
extent
degree
determined
by
trajectory
(i.e.
retrogenesis)
and/or
state.
We
obtained
microstructural
and
perfusion
measures
using
data
from
Human
Connectome
Project
Aging
(HCP-A),
complemented
a
meta-analysis
involving
maps
calibre
macrovascular
volume.
Our
results
(1)
while
tracts
appear
last
finish
myelinating
display
slowest
pattern
not
fully
explained
retrogenesis;
fact,
time
courses
emergence
myelination
give
rise
opposite
associations
decline;
(2)
earlier
higher
mean
axon
lower
degrees
aging;
(3)
tend
exhibit
relatively
sustained
CBF
rate
lengthening
arterial
transit
times
(ATT),
suggestive
collateral
blood
supply.
These
were
sex
dependent
tract-specific
manner.
Future
work
will
investigate
whether
these
ultimately
influenced
each
tract's
demand
role
flow.
Язык: Английский
The development of aperiodic and periodic resting-state power between early childhood and adulthood: new insights from optically pumped magnetometers
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Май 14, 2024
Abstract
Neurophysiological
signals,
comprised
of
both
periodic
(e.g.,
oscillatory)
and
aperiodic
non-oscillatory)
activity,
undergo
complex
developmental
changes
between
childhood
adulthood.
With
much
the
existing
literature
primarily
focused
on
features
brain
function,
our
understanding
signals
is
still
in
its
infancy.
Here,
we
are
first
to
examine
age-related
(peak
frequency
power)
(slope
offset)
activity
using
optically
pumped
magnetometers
(OPMs),
a
new,
wearable
magnetoencephalography
(MEG)
technology
that
particularly
well-suited
for
studying
development.
We
examined
these
spectral
sample
(
N
=65)
toddlers
(1-3
years),
children
(4-5
young
adults
(20-26
(27-38
years).
Consistent
with
extant
literature,
found
significant
decreases
slope
offset,
peak
power
were
frequency-specific;
show
effect
sizes
also
varied
across
regions.
This
work
not
only
adds
growing
body
highlighting
advantages
OPMs,
especially
development,
but
contributes
novel
information
regarding
variation
neurophysiological
age
brain.
Язык: Английский
Head And Shoulders - The Impact Of An Extended Head Model On The Simulation And Optimization Of Transcranial Electric Stimulation
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 30, 2024
Abstract
Electric
field
calculations
are
increasingly
used
for
dose
characterization
of
transcranial
electrical
stimulation
(tES),
but
existing
open-source
head
models
inaccurate
extracephalic
montages
that
include
electrodes
placed
on
the
neck
or
shoulder.
We
introduce
“Ernie
Extended”
model,
an
MRI-
and
CT-derived
model
extending
to
upper
shoulder
region.
Simulations
tES
targeting
cerebellum
supplementary
motor
area
show
significant
differences
in
electric
fields
when
using
Ernie
Extended
compared
non-extended
model.
Additionally,
we
propose
electrode
layout
complements
electroencephalography
10–
20
system
with
positions.
demonstrate
use
this
optimizing
multi-electrode
cerebellar
stimulation,
enhancing
focality
reducing
off-target
particularly
spinal
cord.
Our
results
highlight
practical
value
accurately
characterizing
doses
produced
by
more
caudal
brain
regions.
Язык: Английский