Advances in Microbiome‐Based Therapeutics for Dermatological Disorders: Current Insights and Future Directions

Experimental Dermatology, Год журнала: 2024, Номер 33(12)

Опубликована: Дек. 1, 2024

ABSTRACT The human skin hosts an estimated 1000 bacterial species that are essential for maintaining health. Extensive clinical and preclinical studies have established the significant role of microbiome in dermatological disorders such as atopic dermatitis, psoriasis, diabetic foot ulcers, hidradenitis suppurativa cancers. In these conditions, is not only altered but, some cases, implicated disease pathophysiology. Microbiome‐based therapies (MBTs) represent emerging category live biotherapeutic products with tremendous potential a novel intervention platform diseases. Beyond using wild‐type strains native to skin, can be enhanced express targeted therapeutic molecules, offering more tailored treatment approaches. This review explores various common disorders, particular focus on development MBTs treating conditions.

Язык: Английский

Multi-omics analysis of outer membrane vesicles from P. goldsteinii in a psoriasis mouse model

Life Sciences, Год журнала: 2025, Номер unknown, С. 123776 - 123776

Опубликована: Май 1, 2025

Язык: Английский

The Causal Effect Between Human Microbiota and Scabies: A Study from the Genetic Perspective

Clinical Cosmetic and Investigational Dermatology, Год журнала: 2024, Номер Volume 17, С. 2803 - 2812

Опубликована: Дек. 1, 2024

Previous studies have indicated that human flora may affect the development of scabies, however, no proven a causal relationship between and which would be detrimental to future in-depth on scabies.

Язык: Английский