Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown, С. 111 - 120
Опубликована: Май 7, 2024
Abstract
‘A
conceptual
theory
of
the
Goal
Inhibition
System’
(GIS)
presents
an
updated
version
what
was
known
previously
as
Behavioural
System.
It
emphasizes
some
minor,
mostly
terminological
differences,
that
can
have
a
major
impact
on
interpretation.
summarizes
key
conclusions
four
previous
chapters.
The
ethoexperimental
analysis
Chapter
2
elucidates
differences
between
fear
and
anxiety
from
stimulus
perspective
but
learning
3
makes
cognitive/functional
more
attractive.
Importantly,
derived
in
3,
attraction
result
gain
or
omission
loss,
repulsion
loss
gain,
goal
conflict
concurrent
incompatible
repulsion.
is
sensitive
to
anxiolytic
drugs,
defining
GIS
accounting
for
its
outputs
inhibition,
arousal,
attention,
risk
assessment.
A
modular
diagram
whole
pointers
neural
basis
are
provided.
Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 7, 2024
Abstract
The
Neuropsychology
of
Anxiety
first
appeared
in
1982
as
the
volume
Oxford
Psychology
Series,
and
it
quickly
established
itself
classic
work
on
subject.
It
second
edition
(appearing
2000)
have
been
cited
at
a
steadily
increasing
rate
passing
500/year
2017.
field
has
continued
to
expand
last
quarter
century
necessitating
this
third
edition.
This
completely
updated
revised
(with
many
figures
converted
colour)
retains
original
core
concepts
while
expanding
often
simplifying
details.
includes
new
chapter
prefrontal
cortex,
which
integrates
frontal
hippocampal
views
anxiety
an
extensively
modified
personality
providing
basis
for
further
developments
Reinforcement
Sensitivity
Theory.
book
is
essential
postgraduate
students
researchers
experimental
psychology
neuroscience,
well
all
clinical
psychologists
psychiatrists.
Frontiers in Neuroscience,
Год журнала:
2024,
Номер
18
Опубликована: Апрель 8, 2024
Periaqueductal
gray
(PAG),
an
integration
center
for
neuronal
signals,
is
located
in
the
midbrain
and
regulates
multiple
physiological
pathological
behaviors,
including
pain,
defensive
aggressive
anxiety
depression,
cardiovascular
response,
respiration,
sleep-wake
behaviors.
Due
to
different
neuroanatomical
connections
functional
characteristics
of
four
columns
PAG,
subregions
PAG
synergistically
regulate
various
instinctual
In
current
review,
we
summarized
role
possible
neurobiological
mechanism
regulation
anxiety,
depression
from
perspective
up-down
circuits
PAG.
Furthermore,
proposed
potential
clinical
applications
Knowledge
these
aspects
will
give
us
a
better
understanding
key
behaviors
provide
directions
future
treatments.
Journal of Neuroscience,
Год журнала:
2024,
Номер
44(17), С. e1538232024 - e1538232024
Опубликована: Апрель 24, 2024
Pain
is
considered
a
multidimensional
experience
that
embodies
not
merely
sensation,
but
also
emotion
and
perception.
As
appropriate
for
this
complexity,
pain
represented
processed
by
an
extensive
matrix
of
cortical
subcortical
structures.
Of
these
structures,
the
cerebellum
gaining
increasing
attention.
Although
association
between
both
acute
chronic
have
been
extensively
detailed
in
electrophysiological
neuroimaging
studies,
deep
understanding
what
functions
are
mediated
associations
lacking.
Nevertheless,
available
evidence
implies
lobules
IV–VI
Crus
I
especially
pertinent
to
processing,
anatomical
studies
reveal
regions
connect
with
higher-order
structures
sensorimotor,
emotional,
cognitive
function.
Therefore,
we
speculate
exerts
modulatory
role
via
its
communication
sites
executive,
reward,
limbic
On
basis,
review,
propose
numerous
ways
which
might
contribute
pain,
drawing
particular
attention
emotional
elements
pain.
In
addition,
emphasise
importance
advancing
our
knowledge
about
relationship
discussing
novel
therapeutic
opportunities
capitalize
on
association.
Cortex,
Год журнала:
2024,
Номер
173, С. 175 - 186
Опубликована: Фев. 15, 2024
The
amygdala
and
cerebellum
are
both
evolutionary
preserved
brain
structures
containing
cortical
as
well
subcortical
properties.
For
decades,
the
has
been
considered
fear-center
of
brain,
but
recent
advances
have
shown
that
acts
a
critical
hub
between
systems
shapes
social
affective
behaviors
beyond
fear.
Likewise,
is
dedicated
control
unit
fine-tunes
motor
behavior
to
fit
contextual
requirements.
There
however
increasing
evidence
strongly
influences
processes
domain.
These
insights
broadened
view
on
cerebellum's
functions
also
include
behavior.
Here
we
explore
how
might
interact
in
shaping
based
their
roles
threat
reactivity
reinforcement
learning.
A
novel
mechanistic
neural
framework
cerebellum-amygdala
interactions
will
be
presented
which
provides
for
testable
hypotheses
future
neuroscientific
research
humans.
Frontiers in Cellular Neuroscience,
Год журнала:
2024,
Номер
18
Опубликована: Май 3, 2024
Research
on
bidirectional
communication
between
the
heart
and
brain
has
often
relied
studies
involving
nonhuman
animals.
Dependance
animal
models
offer
limited
applicability
to
humans
a
lack
of
high-throughput
screening.
Recently,
field
3D
cell
biology,
specifically
organoid
technology,
rapidly
emerged
as
valuable
tool
for
studying
interactions
across
organ
systems,
i.e.,
gut-brain
axis.
The
initial
success
indicates
usefulness
cultures
elucidating
intricate
interactivity
autonomic
nervous
system
overall
health.
This
perspective
aims
explore
potential
advancing
in
vitro
modeling
heart-brain
axis
by
discussing
benefits,
applications,
adaptability
technologies.
We
closely
examine
current
state
organoids
conjunction
with
advancements
cardiac
organoids.
Moreover,
we
use
combined
systems
investigate
pathophysiology
provide
platform
treatment
discovery.
Finally,
address
challenges
that
accompany
an
emphasis
generating
tailored
engineering
strategies
further
refinement
dynamic
.
Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown, С. 371 - 430
Опубликована: Май 7, 2024
Abstract
‘Anxiety
and
personality’
links
the
anxiolytic-derived
state
neuropsychology
of
previous
chapters
to
personality
traits.
Traits
are
seen
as
sensitivities
structures,
goal
control
systems,
more
global
modulators
systems.
It
lays
ground
work
for
seeing
psychiatric
disorders
resulting
from
one
or
extreme
sensitivities.
While
main
focus
is
anxiety,
it
also
discusses
implications
Reinforcement
Sensitivity
Theory
(RST)
with
additional
comment
on
Big
5.
reviews
issues
arising
word
meanings,
evolution,
need
biomarkers,
hierarchical
organization,
continuity
versus
discontinuity
provides
recommendation
application
work,
throughout.
distinguishes
neuroticism
trait
a
new
dopaminergic
neurology
reinforcement
sensitivity,
strongly
reinforcers,
first
anxiety
disorder
biomarker,
identifies
problems
existing
RST
scales,
future
neural
solutions.
Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown, С. 241 - 284
Опубликована: Май 7, 2024
Abstract
‘Fundamentals
of
the
septo-hippocampal
system’
derives
a
range
data
principles
from
an
overview
sept-hippocampal
data.
It
reviews
anxiolytic
action
on
system
and
behaviour;
control
rhythmical
slow
activity
(RSA)/‘theta’
activity;
relationship
to
sensory
processing,
working/active
memory,
conditioning,
emotion.
then
discusses
how
approach
understanding
system,
its
anatomy,
role
in
long-term
memory
via
mismatch
detection.
emphasizes
important
affectively
linked
neuromodulatory
systems
hippocampal
function;
hippocampus
at
least
70
chemical
factors,
including
corticosterone/cortisol.
Its
series
are
solidly
based
available
so
all
theories
should
be
judged
against
them.
While
place
severe
limits
assumptions
machinery
theory,
they
not
sufficient
provide
theory
themselves.
Oxford University Press eBooks,
Год журнала:
2024,
Номер
unknown, С. 167 - 188
Опубликована: Май 7, 2024
Abstract
‘What
do
hippocampal
cell
fields
represent?’
argues
against
the
conventional
idea
of
‘place’
fields.
Clear
eyeblink,
time,
displace,
and
other
‘fields’
argue
place
per
se;
as
failures
most
obvious
to
map
space
either
externally
or
in
brain;
with
‘remapping’
being
inconsistent
any
truly
spatial
metric.
As
visual
firing
is
not
a
good
guide
information
coded.
Hippocampal
easily
understood
receipt
efference
copies
from
distributed
assemblies
that
code
available
goals;
dorsal
ventral
cells
largely
echoing
cortical
trends
‘where’
‘what’
goal,
respectively.
Head
direction
cells,
path
integration,
topographic
mapping
hippocampus
are
also
discussed.
