Clinical Considerations in the Treatment of Idiopathic Hypersomnia

Sleep Medicine, Год журнала: 2024, Номер 119, С. 488 - 498

Опубликована: Май 7, 2024

Idiopathic hypersomnia typically is a chronic and potentially debilitating neurologic sleep disorder, characterized by excessive daytime sleepiness. In addition to sleepiness, idiopathic symptoms can include severe inertia; long, unrefreshing naps; long time; cognitive dysfunction. Patients with may experience significant impact on their quality of life, work or school performance, earnings, employment, overall health. Given the complex range associated array treatments available, there need provide guidance treatment clinically relevant recommendations that enhance effective disease management. Identifying appropriate options for requires timely accurate diagnosis, consideration individual patient factors, frequent reassessment symptom severity. 2021, low-sodium oxybate was first receive approval US Food Drug Administration in adults. However, many off-label continue be used. Adjunct nonpharmacologic therapies, including good hygiene, education counseling, use support groups, should recognized recommended when appropriate. This narrative review describes optimal strategies take into account patient-specific as well unique characteristics each medication evolution patient's response treatment. Perspectives measurement management, potential future are also offered.

Язык: Английский

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The association between attention deficit hyperactivity disorder and pregnancy, delivery and neonatal outcomes—an evaluation of a population database

BMC Pregnancy and Childbirth, Год журнала: 2024, Номер 24(1)

Опубликована: Май 15, 2024

Abstract Background Attention deficit hyperactivity disorder (ADHD) is one of the more common neuropsychiatric disorders in women reproductive age. Our objective was to compare perinatal outcomes between with an ADHD diagnosis and those without. Methods A retrospective population-based cohort study utilizing Healthcare Cost Utilization Project, Nationwide Inpatient Sample (HCUP-NIS) United States database. The included all who either delivered or experienced maternal death from 2004 2014. Perinatal were compared ICD-9 Results Overall, 9,096,788 met inclusion criteria. Amongst them, 10,031 had a ADHD. Women ADHD, without, likely be younger than 25 years age; white; smoke tobacco during pregnancy; use illicit drugs; suffer chronic hypertension, thyroid disorders, obesity ( p < 0.001 for all). group, higher rate hypertensive pregnancy (HDP) (aOR 1.36, 95% CI 1.28–1.45, 0.001), cesarean delivery 1.19, 1.13–1.25, chorioamnionitis 1.34, 1.17–1.52, infection 1.33, 1.19–1.5, 0.001). Regarding neonatal outcomes, patients small-for-gestational-age neonate (SGA) 1.3, 1.17–1.43, congenital anomalies 2.77, 2.36–3.26, Conclusion incidence myriad complications, including delivery, HDP, SGA neonates.

Язык: Английский

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Association of socioeconomic status with unintended pregnancy and induced abortion in married couples: An analysis of the 2021 national survey data in Japan

Clinical Epidemiology and Global Health, Год журнала: 2024, Номер 30, С. 101814 - 101814

Опубликована: Окт. 6, 2024

BackgroundAn association of the major indicators socioeconomic status with unintended pregnancy and induced abortion in married couples has not been investigated Japan, we it using recent nationwide survey data Japan.MethodsData from National Fertility Survey 2021 which evaluated outcomes intentions previous pregnancies couples, were used. Number pregnancies, abortions, ending used as outcomes, number was analyzed among who experienced an pregnancy. Associations current educational attainment, employment status, household income Poisson regression analysis. A complete-case analysis conducted for dealing missing data, well multiple imputation.ResultsAverage per junior high school graduates highest attainments wives husbands. The adjusted showed that graduate husbands significantly associated higher regardless methods. In addition, or training abortions. significant between observed.ConclusionThis study a lower attainment husband abortions Japan.

Язык: Английский

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A Comparative Analysis of Artificial Intelligence Platforms: ChatGPT-4o and Google Gemini in Answering Questions About Birth Control Methods

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Background Birth control methods (BCMs) are often underutilized or misunderstood, especially among young individuals entering their reproductive years. With the growing reliance on artificial intelligence (AI) platforms for health-related information, this study evaluates performance of ChatGPT-4o and Google Gemini in addressing commonly asked questions about BCMs. Methods Thirty questions, derived from American College Obstetrics Gynecologists (ACOG) website, were posed to both AI platforms. Questions spanned four categories: general contraception, specific contraceptive types, emergency other topics. Responses evaluated using a five-point rubric assessing Relevance, Completeness, Lack False Information (RCL). Overall scores calculated by averaging scores. Statistical analysis, including Wilcoxon Signed-Rank test, Friedman Kruskal-Wallis was performed compare metrics. Results provided high-quality responses birth control-related queries, with overall 4.38 ± 0.58 4.37 0.52, respectively, categorized as "very good" "excellent." demonstrated higher lack false based descriptive statistics (4.70 0.60 vs. 4.47 0.73), while outperformed relevance, statistically significant difference (4.53 0.57 4.30 0.70, p = 0.035, large effect size). Completeness comparable (p 0.655). analyses revealed no differences 0.548), though potential trend stronger "Other Topics" category. Within-model variability showed had more pronounced metrics (moderate size, Kendall's W 0.357), exhibited smaller (Kendall's 0.165). These findings suggest that offer reliable complementary tools knowledge gaps nuanced strengths warrant further exploration. Conclusions accurate BCM-related slight strengths. underscore tools, public health information needs, particularly seeking guidance contraception. Further studies larger datasets may elucidate between

Язык: Английский

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Predictors of Fetal Attachment, Anxiety, Stress, and Worry in Unintended Pregnancies in the Primary Care Center in Southern Iran

Iranian Journal of Nursing and Midwifery Research, Год журнала: 2025, Номер 30(1), С. 97 - 102

Опубликована: Янв. 1, 2025

Despite the prevalence of unintended pregnancies, little is known about connections between psychosocial and sociodemographic characteristics. This study explored predictors fetal attachment, worry, anxiety, stress in pregnancies. descriptive, cross-sectional was conducted on 229 father mother pairs from two primary healthcare centers Fars province southern Iran. Data were collected a face-to-face survey using Parents Fetal Attachment Scale, Spielberger State-Trait Anxiety Inventory (STAI), Cambridge Worry Scale (CWS), Perceived Stress (PSS), Parental Scale. The participants selected two-stage random cluster sampling method November 2022 to February 2023. analyzed SPSS software binary logistic multiple linear regression tests. According findings, education level previous parenting experience found have statistically significant effect attachment levels mothers (F4,224 = 5.14; p < 0.05). However, there no difference perceived fathers (p > Previous significantly affected mothers' anxiety (odd ratio: 3.20; age variable had relationship with results, unwanted pregnancy stress, worry. It recommended that enhance mental health couples who experienced pregnancy, platform should be provided for development their environment.

Язык: Английский

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Association of contraception use and pregnancy intention with perinatal depression risk among Omani mothers—a longitudinal cohort study

Frontiers in Global Women s Health, Год журнала: 2025, Номер 6

Опубликована: Янв. 31, 2025

Unplanned pregnancy is significantly associated with an increased risk of perinatal depression (antenatal and postnatal depression), emphasizing its prevalence potentially detrimental effects on both maternal child health. This study aimed to investigate the association contraception use intention among Omani mothers. A prospective longitudinal design was employed in mothers attending antenatal health care services Oman. Perinatal assessed using Edinburgh Postpartum Depression Scale during third trimester postpartum visits. Multiple linear regression analyses were utilized explore relationships between pregnancy-related factors, use, sociodemographic variables. The involved 300 participants a mean age 30.8 years (SD = 5.47). majority reported planned (74.0%), no (66.0%), being multiparous (72.7%). higher proportion (87.8%) women pregnancies primiparous (p < 0.001). Besides family structure (core family, p 0.025) monthly income (1,000 OMR or below, 0.021), who pregnant for first time 0.001), those 0.001) did not contraception. models showed significant scores 0.001, 95% CI 0.401-0.603) according Scale. findings suggest that unplanned warrant attention early detection preventive interventions, irrespective their emotional stance. Incorporating routine mental screening into can facilitate detection, targeted contributing improved well-being.

Язык: Английский

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Interest in Contraceptive Information and Initiation Among Adolescents Hospitalized With Psychiatric Disorders

Journal of Adolescent Health, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

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Assessment of maternal healthcare services among the women of reproductive age in the rural municipality of Nepal: a cross-sectional study

BMJ Public Health, Год журнала: 2025, Номер 3(1), С. e000916 - e000916

Опубликована: Фев. 1, 2025

Background Maternal Mortality Ratio is one of the crucial indicators Sustainable Development Goal-3, which to be achieved below 70 per 100 000 live births by 2030. It essential assess current status antenatal care (ANC), uptake skilled birth attendants (SBAs), and postnatal (PNC) improve health a mother child in developing countries like Nepal. This study assesses utilisation factors associated with maternal healthcare services among reproductive-aged women Shubhakalika Rural municipality Methods A cross-sectional using proportionate simple random sampling was performed select 180 participants. Nepali-translated tool based on Andersen’s Behaviour Model service used collect data. ANC services, SBAs, PNC continuum were dependent variables while independent categorised into predisposing, enabling need factors. Bivariate multivariable regression analysis Statistical Package Social Sciences V.20 determine association between variables. All tests set at CI 95%. Results included participants mean (±SD) age 24.3±4.9 years. Women whose husbands completed formal schooling more likely have four visits (adjusted OR (AOR)=3.2, CI=1.0–10.3). planned pregnancy significantly use (AOR=10.3, CI=3.5–30.3), institutional delivery (AOR=3.2, CI=1.1–9.3) (AOR=7.4, CI=1.4–37.8). Ethnicity (AOR=2.4, CI=1.1–5.4), education (AOR=2.7, CI=1.0–7.7), having problems receiving (AOR=4.5, CI=1.5–15.2) distance nearest facilities less than 30 minutes CI=1.0–5.7) delivery. Similarly, who 18 years or above time marriage attend least CI=1.5–6.5) under 18. Meanwhile, insurance visit (AOR=0.3, CI=0.1–0.6) compared those without insurance. Conclusion pregnancies, higher access comprehensive including ANC, PNC. demonstrated proximity facilities, lower ethnic groups deprived services. These results emphasise address socio-demographic disparities accessibility. Since, programmes facilitate efforts should focus expanding coverage reach target population effectively, such as newly married couples.

Язык: Английский

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Adverse childhood experiences and the impact on pregnancy intention, a cross-sectional study

Journal of Psychosomatic Obstetrics & Gynecology, Год журнала: 2025, Номер 46(1)

Опубликована: Фев. 11, 2025

Objectives Adverse Childhood Experiences (ACE) may be associated with unintended pregnancies (UPs). Our aim was to investigate whether there is an association between a history of ACE, type ACE or number and the risk for UPs if this mediated by psychiatric vulnerabilities.

Язык: Английский

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Pregnancy intention, preconception health, health behaviours, and information and health advice seeking among expectant male partners

BMC Primary Care, Год журнала: 2025, Номер 26(1)

Опубликована: Фев. 12, 2025

Attempting pregnancy as a conscious decision (pregnancy intention) can impact the likelihood that future parent receives or seeks preconception health information, initiates discussions with professionals, and ultimately optimises their behaviours in preparation for healthy child. Knowledge about relationship between men's intention is only emerging. This study aimed to describe status, behaviours, information- advice-seeking of male expectant partners, explore differences these factors based on intention. An online retrospective cross-sectional survey was completed by reproductive partners pregnant females. Their assessed using London Measure Unplanned Pregnancy (LMUP). Participants were recruited via social media all variables self-reported partners. Chi-square tests examined LMUP categories (planned ambivalent/unplanned). Of 156 who consented participation, 138 questions included analysis. Most reported partner's current planned (n = 90;65.2%), less than half looking finding information becoming (40.0%). Expectant more often physical exercise three months before compared unplanned/ambivalent (p 0.001). ambivalent/unplanned experienced longstanding illness, disability, infirmity 0.002) disregarded contraception < Despite perceiving good excellent health, undertaking exercise, numerous had overweight. Further research exploring life plan process males chronic illness disability may help promote planning amongst this sub-population. large-scale studies are needed enable clinicians better understand intentions policy makers formulate policies at supporting awareness.

Язык: Английский

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