Mechanical and Biological Properties of Additive Manufactured Polyester‐Based Scaffolds Treated by Surface Etching DOI Open Access
Xia Gao,

Cong Yang,

Junlin Zhu

и другие.

Macromolecular Chemistry and Physics, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Abstract Currently, material extrusion‐based additive manufacturing (MEAM) technique, also known as fused filament fabrication (FFF) technique has been widely used to prepare customized porous scaffolds for bone tissue engineering. However, often lack desirable osteogenic properties due the poor hydrophilicity of polymer materials FFF technique. In this work, biocompatible suitable are prepared by blending polycaprolactone (PCL), polylactic acid (PLA), and tricalcium phosphate (TCP) at various compositions. These composite subsequently printed into cylindrical with controllable pore sizes ranging from 200–800 µm, regulating infill density during process. The FFF‐printed have highest modulus a PLA/PCL ratio 0.7 size ≈ 200 µm. Furthermore, surface treatment is applied these in sodium hydroxide solution. As result, roughness, serum adsorption significantly enhanced. More importantly, surface‐treated can promote differentiation MC3T3‐E1 cells, comparable commercial Bio‐Oss substitutes. Thus, study offers cost‐effective development bioactive potential engineering applications.

Язык: Английский

Mechanical and Biological Properties of Additive Manufactured Polyester‐Based Scaffolds Treated by Surface Etching DOI Open Access
Xia Gao,

Cong Yang,

Junlin Zhu

и другие.

Macromolecular Chemistry and Physics, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Abstract Currently, material extrusion‐based additive manufacturing (MEAM) technique, also known as fused filament fabrication (FFF) technique has been widely used to prepare customized porous scaffolds for bone tissue engineering. However, often lack desirable osteogenic properties due the poor hydrophilicity of polymer materials FFF technique. In this work, biocompatible suitable are prepared by blending polycaprolactone (PCL), polylactic acid (PLA), and tricalcium phosphate (TCP) at various compositions. These composite subsequently printed into cylindrical with controllable pore sizes ranging from 200–800 µm, regulating infill density during process. The FFF‐printed have highest modulus a PLA/PCL ratio 0.7 size ≈ 200 µm. Furthermore, surface treatment is applied these in sodium hydroxide solution. As result, roughness, serum adsorption significantly enhanced. More importantly, surface‐treated can promote differentiation MC3T3‐E1 cells, comparable commercial Bio‐Oss substitutes. Thus, study offers cost‐effective development bioactive potential engineering applications.

Язык: Английский

Процитировано

0