Coordination Chemistry Reviews, Год журнала: 2025, Номер 535, С. 216641 - 216641
Опубликована: Март 30, 2025
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 269, С. 132113 - 132113
Опубликована: Май 6, 2024
Язык: Английский
Процитировано
37
Coordination Chemistry Reviews, Год журнала: 2024, Номер 516, С. 215986 - 215986
Опубликована: Июнь 2, 2024
Язык: Английский
Процитировано
21
Chemical Engineering Journal, Год журнала: 2024, Номер 488, С. 151039 - 151039
Опубликована: Апрель 5, 2024
Язык: Английский
Процитировано
14
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 275, С. 133599 - 133599
Опубликована: Июль 1, 2024
Язык: Английский
Процитировано
12
Advanced Functional Materials, Год журнала: 2024, Номер 34(26)
Опубликована: Фев. 23, 2024
Abstract Endometriosis is a prevalent gynecological disorder characterized by the presence of endometrial‐like tissue outside uterus, causing chronic pelvic pain, painful periods, and infertility. Despite common use hormone therapy surgical lesion excision in its treatment, there remain significant postoperative risks potential side effects, with high recurrence rate. An efficient nonsurgical treatment for this condition therefore urgently needed. In study, an interventional hydrogel microsphere near‐infrared (NIR)‐controlled curcumin release developed non‐invasive thermal endometriosis. The microspheres demonstrate good biocompatibility photothermal activities, death endometrial stromal cells under NIR controlled (Cur) release. When injected into endometriotic lesions stimulated light, (Cur‐FeHMPs) can raise temperature to 43.65 °C, inducing elimination. Furthermore, from inhibits proinflammatory environment Cur‐FeHMPs combination present novel strategy endometriosis treatment.
Язык: Английский
Процитировано
10
Applied Materials Today, Год журнала: 2024, Номер 38, С. 102215 - 102215
Опубликована: Май 3, 2024
Язык: Английский
Процитировано
9
Advanced Science, Год журнала: 2023, Номер 11(8)
Опубликована: Ноя. 9, 2023
Abstract Near‐infrared (NIR) light is well‐suited for the optical imaging and wireless phototherapy of malignant diseases because its deep tissue penetration, low autofluorescence, weak scattering, non‐invasiveness. Rare earth nanoparticles (RENPs) are promising NIR‐responsive materials, owing to their excellent physical chemical properties. The 4f electron subshell lanthanides, main group rare elements, has rich energy‐level structures. This facilitates broad‐spectrum light‐to‐light conversion other forms energy, such as thermal energies. In addition, abundant loadable modifiable sites on surface offer favorable conditions functional expansion RENPs. this review, authors systematically discuss processes mechanisms underlying response RENPs NIR summarize recent advances in applications imaging, photothermal therapy, photodynamic photoimmunotherapy, optogenetics, light‐responsive drug release. Finally, challenges opportunities application under activation considered.
Язык: Английский
Процитировано
22
Advanced Healthcare Materials, Год журнала: 2024, Номер 13(17)
Опубликована: Март 14, 2024
The Golgi apparatus (GA) is central in shuttling proteins from the endoplasmic reticulum to different cellular areas. Therefore, targeting GA precisely destroy its through local heat could induce apoptosis, offering a potential avenue for effective cancer therapy. Herein, GA-targeted photothermal agent based on protein anchoring introduced enhanced therapy of tumor modification near-infrared molecular dye with maleimide derivative and benzene sulfonamide. can actively target covalently anchor sulfhydryl proteins, thereby increasing retention within GA. Under laser irradiation, generated by efficiently disrupts situ, leading dysfunction ultimately inducing cell apoptosis. In vivo experiments demonstrate that treat tumors significantly reduce side effects.
Язык: Английский
Процитировано
6
Advanced Functional Materials, Год журнала: 2024, Номер 34(37)
Опубликована: Май 15, 2024
Abstract Carrier‐free nanodrugs that integrate chemodrugs and other therapeutic agents demonstrate good efficacy minimized side effects, showing promise for combined therapy. However, a key challenge lies in enhancing the bioavailability potential of through controllable assembly process. Herein, carrier‐free photothermal nanodrug (ZPQ NPs) is constructed flavonol‐driven with amine‐substituted perylene diimide enhanced chemo‐photothermal cancer The flavonol, particularly quercetin, facilitates J‐aggregation derivatives within contributes to multiple improvements, including red‐shifted absorption, fluorescence intensity, improved conversion efficiency as well excellent photostability. Moreover, also demonstrates cellular uptake intracellular reactive oxygen species scavenging capability. combination quercetin effect effectively kills cells, alleviates inflammation following Guided by vivo imaging, application ZPQ NPs results complete tumor elimination inhibits recurrence This work presents straightforward strategy constructing exhibit simultaneous enhancements both photophysical properties biological activity.
Язык: Английский
Процитировано
6
Bioactive Materials, Год журнала: 2024, Номер 41, С. 271 - 292
Опубликована: Июль 24, 2024
Periodontitis is an inflammatory disease caused by bacterial biofilms, which leads to the destruction of periodontal tissue. Current treatments, such as mechanical cleaning and antibiotics, struggle effectively address persistent inflammation, tissue damage. A new approach involves developing a Janus nanomotor (J-CeM@Au) coating cerium dioxide-doped mesoporous silica (CeM) with gold nanoparticles (AuNPs). This exhibits thermophoretic motion when exposed near-infrared (NIR) laser light due temperature gradient produced photothermal effects asymmetrically distributed AuNPs. The NIR provides energy for propulsion activates nanomotor's antibacterial properties, allowing it penetrate biofilms kill bacteria. Additionally, ability scavenge reactive oxygen species (ROS) can modulate immune response create regenerative environment, promoting healing Overall, this multifunctional offers promising treating periodontitis simultaneously addressing biofilm management modulation autonomous movement.
Язык: Английский
Процитировано
6