Hydroxypropyl methylcellulose reinforced collagen/PVA composite hydrogel wound dressing with self-adaptive, hemostasis and antibacterial ability for wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 304, С. 140811 - 140811

Опубликована: Фев. 12, 2025

Язык: Английский

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Chitosan-modified molybdenum selenide mediated efficient killing of Helicobacter pylori and treatment of gastric cancer

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 275, С. 133599 - 133599

Опубликована: Июль 1, 2024

Язык: Английский

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“Release-Occupy” strategy to fabricate an integrally formed Janus adhesive hydrogel for wearable sensor

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159540 - 159540

Опубликована: Янв. 1, 2025

Язык: Английский

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C-phycocyanin and quaternized chitosan based antibiotic-free hydrogels with antioxidant and antibacterial activity for wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140647 - 140647

Опубликована: Фев. 1, 2025

Язык: Английский

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Procoagulant, antibacterial and antioxidant high-strength porous hydrogel adhesives in situ formed via self-gelling hemostatic microsheets for emergency hemostasis and wound repair

Biomaterials, Год журнала: 2024, Номер 315, С. 122936 - 122936

Опубликована: Окт. 31, 2024

Язык: Английский

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Facile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium‐Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 31, 2025

Multifunctional hydrogels hold significant promise for promoting the healing of infected wounds but often fall short in inhibiting antibiotic-resistant pathogens, and their clinical translation is limited by complex preparation processes high costs. In this study, a multifunctional hydrogel developed combining metal-phenolic networks (MPNs) formed tannic acid (TA) gallium ions (Ga3⁺) with chitosan (CS) through simple one-step method. The resulting CS-TA-Ga3⁺ (CTG) cost-effective exhibits desirable properties, including injectability, self-healing, pH responsiveness, hemostasis, antioxidant, anti-inflammatory, antibacterial activities. Importantly, CTG are effective against pathogens due to unique mechanism Ga3⁺. vivo studies demonstrate that promotes follicle formation collagen deposition, accelerating blood loss, suppressing bacterial growth, modulating inflammatory microenvironment. These findings highlight hydrogel's potential as an advanced translational dressing enhancing wounds.

Язык: Английский

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Material Design, Fabrication Strategies, and the Development of Multifunctional Hydrogel Composites Dressings for Skin Wound Management

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Фев. 17, 2025

The skin is fragile, making it very vulnerable to damage and injury. Untreated wounds can pose a serious threat human health. Three-dimensional polymer network hydrogels have broad application prospects in wound dressings due their unique properties structure. therapeutic effect of traditional limited, while multifunctional composite show greater potential. Multifunctional regulate moisture through formula adjustment. Moreover, be combined with bioactive ingredients improve performance healing applications. Stimulus-responsive respond specifically the environment meet needs different stages. This review summarizes material types, structure, properties, design considerations, formulation strategies for hydrogel used healing. We discuss various types recently developed dressings, highlights importance tailoring physicochemical addresses potential challenges preparing dressings.

Язык: Английский

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Self‐Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Hydrogels are soft, tissue-like materials that have great potential as wound dressings. However, most hydrogels unsatisfactory in achieving whole-layer regeneration of diabetic wounds due to the complex pathological microenvironment and irregular shapes. Here, a glucose-responsive self-adaptive phenylboronic acid (PBA) hydrogel solubilized strong antioxidant flavonoids (Gel-Flavonoids) is developed via dynamic borate bonds. The Gel-Flavonoids system can spontaneously confirm shape release high-glucose effectively eliminate reactive oxygen species (ROS). optimized demonstrate remarkable efficacy inhibiting inflammation activating fibroblasts endothelial cells through CD36-activated lipid metabolism macrophages significantly superior commercial dressings (3M) healing rate (> 93%, 14 days) effect. This study obtained multidimensional repair wounds, reveal underlying therapeutic mechanisms, offering promising insight guide development medical treat wounds.

Язык: Английский

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Calcium-ion-driving assembly of polysaccharide deriving from Zizyphus jujuba to hemostatic hydrogel for treating diabetic wound

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141896 - 141896

Опубликована: Март 1, 2025

Язык: Английский

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An Integrated Janus Patch with Asymmetric Tissue Adhesion for Enhanced Postoperative Adhesion Prevention

Polymer science & technology., Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

Язык: Английский

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