Lateral Spacing of TiO2 Nanotube Coatings Modulates In Vivo Early New Bone Formation DOI Creative Commons
Andreea Mariana Negrescu, Iuliana Ionașcu,

Madalina Georgiana Necula

и другие.

Biomimetics, Год журнала: 2025, Номер 10(2), С. 81 - 81

Опубликована: Янв. 28, 2025

Due to the bio-inert nature of titanium (Ti) and subsequent accompanying chronic inflammatory response, an implant’s stability function can be significantly affected, which is why various surface modifications have been employed, including deposition oxide (TiO2) nanotubes (TNTs) onto native through anodic oxidation method. While influence nanotube diameter on cell behaviour osteogenesis very well documented, information regarding effects lateral spacing in vivo new bone formation process insufficient hard find. Considering this, present study’s aim was evaluate mechanical properties osteogenic ability two types TNTs-based pins with different spacing, e.g., 25 nm 92 (spTNTs). The TNT-coated implants were characterised from a morphological point view (tube diameter, tube length) using scanning electron microscopy (SEM). In addition, chemical composition evaluated X-ray photoelectron spectroscopy, while roughness topography atomic force (AFM). Finally, implants’ hardness elastic modulus investigated nanoindentation measurements. histologically (haematoxylin eosin—HE staining) at 6 30 days post-implantation rat model. Mechanical characterisation revealed that morphologies presented similar strength, but, terms roughness, spTNTs exhibited higher average roughness. microscopic examination 1 month (57.21 ± 34.93) capable promoting early tissue greater extent than TNTs-coated (24.37 6.5), difference thickness newly formed ~32.84 µm, thus highlighting importance this parameter when designing future dental/orthopaedic implants.

Язык: Английский

Lateral Spacing of TiO2 Nanotube Coatings Modulates In Vivo Early New Bone Formation DOI Creative Commons
Andreea Mariana Negrescu, Iuliana Ionașcu,

Madalina Georgiana Necula

и другие.

Biomimetics, Год журнала: 2025, Номер 10(2), С. 81 - 81

Опубликована: Янв. 28, 2025

Due to the bio-inert nature of titanium (Ti) and subsequent accompanying chronic inflammatory response, an implant’s stability function can be significantly affected, which is why various surface modifications have been employed, including deposition oxide (TiO2) nanotubes (TNTs) onto native through anodic oxidation method. While influence nanotube diameter on cell behaviour osteogenesis very well documented, information regarding effects lateral spacing in vivo new bone formation process insufficient hard find. Considering this, present study’s aim was evaluate mechanical properties osteogenic ability two types TNTs-based pins with different spacing, e.g., 25 nm 92 (spTNTs). The TNT-coated implants were characterised from a morphological point view (tube diameter, tube length) using scanning electron microscopy (SEM). In addition, chemical composition evaluated X-ray photoelectron spectroscopy, while roughness topography atomic force (AFM). Finally, implants’ hardness elastic modulus investigated nanoindentation measurements. histologically (haematoxylin eosin—HE staining) at 6 30 days post-implantation rat model. Mechanical characterisation revealed that morphologies presented similar strength, but, terms roughness, spTNTs exhibited higher average roughness. microscopic examination 1 month (57.21 ± 34.93) capable promoting early tissue greater extent than TNTs-coated (24.37 6.5), difference thickness newly formed ~32.84 µm, thus highlighting importance this parameter when designing future dental/orthopaedic implants.

Язык: Английский

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