Analytical Chemistry,
Год журнала:
2019,
Номер
91(23), С. 14803 - 14807
Опубликована: Сен. 25, 2019
This
study
reports
a
microfluidic
chip-based
wearable
colorimetric
sensor
for
detecting
sweat
glucose.
The
device
consisted
of
five
channels
branching
out
from
the
center
and
connected
to
detection
microchambers.
microchannels
could
route
excreted
epidermis
microchambers,
each
them
was
integrated
with
check
valve
avoid
risk
backflow
chemical
reagents
microchamber.
microchambers
contained
pre-embedded
glucose
oxidase
(GOD)–peroxidase–o-dianisidine
sensing
in
sweat.
It
found
that
color
change
caused
by
enzymatic
oxidation
o-dianisidine
show
more
sensitive
response
than
conventional
GOD–peroxidase–KI
system.
perform
parallel
detections
at
one
time.
obtained
linear
range
0.1–0.5
mM
limit
0.03
mM.
also
used
detect
samples
group
subjects
engaged
both
fasting
postprandial
trials.
results
showed
our
can
reveal
subtle
differences
existing
concentration
after
oral
uptake.
Chemical Reviews,
Год журнала:
2019,
Номер
119(8), С. 5461 - 5533
Опубликована: Янв. 28, 2019
Bio-integrated
wearable
systems
can
measure
a
broad
range
of
biophysical,
biochemical,
and
environmental
signals
to
provide
critical
insights
into
overall
health
status
quantify
human
performance.
Recent
advances
in
material
science,
chemical
analysis
techniques,
device
designs,
assembly
methods
form
the
foundations
for
uniquely
differentiated
type
technology,
characterized
by
noninvasive,
intimate
integration
with
soft,
curved,
time-dynamic
surfaces
body.
This
review
summarizes
latest
this
emerging
field
"bio-integrated"
technologies
comprehensive
manner
that
connects
fundamental
developments
chemistry,
engineering
sensing
have
potential
widespread
deployment
societal
benefit
care.
An
introduction
chemistries
materials
active
components
these
contextualizes
essential
design
considerations
sensors
associated
platforms
appear
following
sections.
The
subsequent
content
highlights
most
advanced
biosensors,
classified
according
their
ability
capture
information.
Additional
sections
feature
schemes
electrically
powering
strategies
achieving
fully
integrated,
wireless
systems.
concludes
an
overview
key
remaining
challenges
summary
opportunities
where
chemistry
will
be
critically
important
continued
progress.
Chemical Society Reviews,
Год журнала:
2018,
Номер
48(6), С. 1566 - 1595
Опубликована: Дек. 6, 2018
Highly
conductive
and
intrinsically
stretchable
electrodes
are
vital
components
of
soft
electronics
such
as
transistors
circuits,
sensors
actuators,
light-emitting
diode
arrays,
energy
harvesting
devices.
Many
kinds
conducting
nanomaterials
with
outstanding
electrical
mechanical
properties
have
been
integrated
elastomers
to
produce
nanocomposites.
Understanding
the
characteristics
these
nanocomposites
assessing
feasibility
their
fabrication
therefore
critical
for
development
high-performance
conductors
electronic
We
herein
summarise
recent
advances
in
based
on
percolation
networks
nanoscale
fillers
elastomeric
media.
After
discussing
material-,
dimension-,
size-dependent
implications,
we
highlight
various
techniques
that
used
reduce
contact
resistance
between
filler
materials.
Furthermore,
categorize
elastomer
matrices
different
stretchabilities
polymeric
chain
structures.
Then,
discuss
toward
use
electronics.
Finally,
provide
representative
examples
device
applications
conclude
review
a
brief
outlook
future
research.
Advanced Functional Materials,
Год журнала:
2018,
Номер
28(35)
Опубликована: Июль 5, 2018
Abstract
Recent
technological
advances
in
nanomaterials
have
driven
the
development
of
high‐performance
light‐emitting
devices
with
flexible
and
stretchable
form
factors.
Deformability
such
is
mainly
achieved
by
replacing
rigid
materials
device
components
their
assemblies
(e.g.,
carbon
nanotubes,
silver
nanowires,
graphene,
quantum
dots)
or
intrinsically
soft
composites
polymers
elastomers).
Downscaling
dimensions
functional
to
nanometer
range
dramatically
decreases
flexural
rigidity,
production
polymer/elastomer
provides
flexibility
stretchability.
Furthermore,
monolithic
integration
these
deformable
sensors
furnishes
resulting
display
various
smart
functions
as
force/capacitive
touch‐based
data
input,
personalized
health
monitoring,
interactive
human–machine
interfacing.
These
ultrathin,
lightweight,
optoelectronic
attracted
widespread
interest
from
scientists
engineers.
Here,
a
comprehensive
review
recent
progress
concerning
displays
presented
focus
on
development,
fabrication
techniques,
designs.
Brief
overviews
an
integrated
system
advanced
cutting‐edge
wearable
are
also
presented,
and,
conclude,
discussion
future
research
outlook
given.
Advanced Functional Materials,
Год журнала:
2019,
Номер
29(19)
Опубликована: Фев. 27, 2019
Abstract
Cardiovascular
disease
is
the
leading
cause
of
death
and
has
dramatically
increased
in
recent
years.
Continuous
cardiac
monitoring
particularly
important
for
early
diagnosis
prevention,
flexible
stretchable
electronic
devices
have
emerged
as
effective
tools
this
purpose.
Their
thin,
soft,
deformable
features
allow
intimate
long‐term
integration
with
biotissues,
which
enables
continuous,
high‐fidelity,
sometimes
large‐area
on
skin
and/or
heart
surface.
In
addition
to
monitoring,
contact
also
crucial
high‐precision
therapies.
Combined
tissue
engineering,
soft
bioelectronics
demonstrated
capability
repair
damaged
tissues.
This
review
highlights
advances
wearable
implantable
based
electronics
cardiovascular
therapy.
First,
wearable/implantable
(e.g.,
electrocardiogram,
blood
pressure,
oxygen
saturation
level)
are
reviewed.
Then,
therapy
mesh
pacing,
ablation,
robotic
sleeves,
stents)
discussed.
Finally,
device‐assisted
engineering
functional
scaffolds
vitro
platforms)
Chemical Reviews,
Год журнала:
2020,
Номер
120(8), С. 3852 - 3889
Опубликована: Март 23, 2020
The
ability
to
fabricate
sensory
systems
capable
of
highly
selective
operation
in
complex
fluid
will
undoubtedly
underpin
key
future
developments
healthcare.
However,
the
abundance
(bio)molecules
these
samples
can
significantly
impede
performance
at
transducing
interface
where
nonspecific
adsorption
(fouling)
both
block
specific
signal
(reducing
sensitivity)
and
greatly
reduce
assay
specificity.
Herein,
we
aim
provide
a
comprehensive
review
discussing
concepts
recent
advances
construction
antifouling
sensors
that
are,
through
use
chemical,
physical,
or
biological
engineering,
operating
sample
matrix
(e.g.,
serum).
We
specifically
highlight
range
molecular
approaches
solid
interfaces
(planar
nanoparticulate)
their
characterization
diverse
vitro
vivo
analyte
proteins,
nucleic
acids,
cells,
neuronal
transmitters)
detection
applications
via
derived
optical
electrochemical
strategies.
those
are
media
based
on
novel
architectures/approaches.
Finally,
perspectives
this
rapidly
evolving
field.
Advanced Materials,
Год журнала:
2019,
Номер
32(18)
Опубликована: Ноя. 13, 2019
Abstract
The
wearable
industry
is
on
the
rise,
with
a
myriad
of
technical
applications
ranging
from
real‐time
health
monitoring,
Internet
Things,
and
robotics,
to
name
but
few.
However,
there
saying
“wearable
not
wearable”
because
current
market‐available
sensors
are
largely
bulky
rigid,
leading
uncomfortable
wearing
experience,
motion
artefacts,
poor
data
accuracy.
This
has
aroused
world‐wide
intensive
research
quest
for
novel
materials,
aim
fabricating
next‐generation
ultra‐lightweight
soft
devices.
Such
disruptive
second‐skin‐like
biosensing
technologies
may
enable
paradigm
shift
1.0
future
2.0
products.
Here,
state‐of‐the‐art
progress
made
in
key
phases
technology,
namely,
wear
→
sense
communicate
analyze
interpret
decide,
summarized.
Without
doubt,
materials
innovation
key,
which
main
focus
discussion.
In
addition,
emphasis
also
given
energy,
multicomponent
integration,
wireless
communication.
