Recent advances in conductive hydrogels: classifications, properties, and applications

Chemical Society Reviews, Год журнала: 2022, Номер 52(2), С. 473 - 509

Опубликована: Дек. 9, 2022

Hydrogel-based conductive materials for smart wearable devices have attracted increasing attention due to their excellent flexibility, versatility, and outstanding biocompatibility. This review presents the recent advances in multifunctional hydrogels electronic devices. First, with different components are discussed, including pure single network based on polymers, additional additives (i.e., nanoparticles, nanowires, nanosheets), double additives. Second, a variety of functionalities, self-healing, super toughness, self-growing, adhesive, anti-swelling, antibacterial, structural color, hydrophobic, anti-freezing, shape memory external stimulus responsiveness introduced detail. Third, applications flexible illustrated strain sensors, supercapacitors, touch panels, triboelectric nanogenerator, bioelectronic devices, robot). Next, current challenges facing summarized. Finally, an imaginative but reasonable outlook is given, which aims drive further development future.

Язык: Английский

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PEDOT:PSS‐Based Bioelectronic Devices for Recording and Modulation of Electrophysiological and Biochemical Cell Signals

Advanced Healthcare Materials, Год журнала: 2021, Номер 10(11)

Опубликована: Май 10, 2021

To understand the physiology and pathology of electrogenic cells corresponding tissue in their full complexity, quantitative investigation transmission ions as well release chemical signals is important. Organic (semi-) conducting materials particular organic electrochemical transistor are gaining importance for electrophysiological recently biochemical due to synthetic nature thus diversity modifiability, biocompatible compliant properties, mixed electronic ionic conductivity featuring ion-to-electron conversion. Here, aim summarize recent progress on development bioelectronic devices utilizing polymer polyethylenedioxythiophene: poly(styrene sulfonate) (PEDOT:PSS) interface electronics biological matter including microelectrode arrays, neural cuff electrodes, transistors, PEDOT:PSS-based biosensors, ion pumps. Finally, material summarized improvement conductivity, stretchability, higher transconductance, or extend field application such cation sensing metabolite recognition. This survey trends PEDOT:PSS sensors highlights potential this multifunctional revolve current technology enable long-lasting, multichannel probes simultaneous recordings from cells.

Язык: Английский

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Microneedle system for tissue engineering and regenerative medicine

Exploration, Год журнала: 2023, Номер 3(1)

Опубликована: Янв. 21, 2023

Abstract Global increasing demand for high life quality and length facilitates the development of tissue engineering regenerative medicine, which apply multidisciplinary theories techniques to achieve structural reconstruction functional recovery disordered or damaged tissues organs. However, clinical performances adopted drugs, materials, powerful cells in laboratory are inescapably limited by currently available technologies. To tackle problems, versatile microneedles developed as new platform local delivery diverse cargos with minimal invasion. The efficient delivery, well painless convenient procedure endow good patient compliance clinic. In this review, we first categorize different microneedle systems models, then summarize their applications medicine mainly involving maintenance rehabilitation end, discuss advantages, challenges, prospects depth future translations.

Язык: Английский

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EDOT-based conjugated polymers accessed via C–H direct arylation for efficient photocatalytic hydrogen production

Chemical Science, Год журнала: 2022, Номер 13(6), С. 1725 - 1733

Опубликована: Янв. 1, 2022

The excellent reactivity toward C–H direct arylation, water wettability and O–C p–π conjugation endow EDOT to be an attractive electron donor unit for CP photocatalysts, yielding unprecedented hydrogen evolution rate up 0.95 mmol h −1 /6 mg catalyst.

Язык: Английский

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Skin-inspired soft bioelectronic materials, devices and systems

Nature Reviews Bioengineering, Год журнала: 2024, Номер 2(8), С. 671 - 690

Опубликована: Июнь 17, 2024

Язык: Английский

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Conductive Polymer‐Coated 3D Printed Microneedles: Biocompatible Platforms for Minimally Invasive Biosensing Interfaces

Small, Год журнала: 2023, Номер 19(14)

Опубликована: Янв. 3, 2023

Conductive polymeric microneedle (MN) arrays as biointerface materials show promise for the minimally invasive monitoring of analytes in biodevices and wearables. There is increasing interest microneedles electrodes biosensing, but efforts have been limited to metallic substrates, which lack biological stability are associated with high manufacturing costs laborious fabrication methods, create translational barriers. In this work, additive manufacturing, provides user design flexibility upscale employed fabricate acrylic-based devices. These devices used platforms produce intrinsically-conductive, polymer-based surfaces based on polypyrrole (PPy) poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS). entirely solid act dry conductive while omitting requirement a seed layer. Two distinct coating methods 3D-printed microneedles, situ polymerization drop casting, enable functionality. The penetrate ex vivo porcine skin grafts without compromising conductivity or morphology demonstrate durability over multiple penetration cycles. non-cytotoxic nature evaluated using human fibroblast cells. proposed strategy offers compelling approach that can be further exploited biosensing.

Язык: Английский

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Boosting the Performance of PEDOT:PSS Based Electronics Via Ionic Liquids

Advanced Materials, Год журнала: 2024, Номер 36(13)

Опубликована: Янв. 8, 2024

The conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) offers superior advantages in electronics due to its remarkable combination of high electrical conductivity, excellent biocompatibility, and mechanical flexibility, making it an ideal material among electronic skin, health monitoring, energy harvesting storage. Nevertheless, pristine PEDOT:PSS films exhibit limitations terms both low conductivity stretchability; while, conventional processing techniques cannot enhance these properties simultaneously, facing the dilemma that highly conductive interconnected domains are susceptible tensile strain. Via modifying with ionic liquids (ILs), not only a synergistic enhancement can be achieved but also requirements for printable bioelectronic satisfied. In this comprehensive review, task providing thorough examination mechanisms applications ILs as modifiers is undertaken. First, theoretical governing interactions between discussed detail. Then, enhanced elucidation underlying through incorporation reviewed. Next, specific ILs-modified relevant devices presented. Last, there concise summary discussion regarding opportunities challenges exciting field.

Язык: Английский

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Recording Quality Is Systematically Related to Electrode Impedance

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Фев. 14, 2024

Extracellular recordings with planar microelectrodes are the gold standard technique for recording fast action potentials of neurons in intact brain. The introduction microfabrication techniques has revolutionized vivo neuronal activity and introduced high-density, multi-electrode arrays that increase spatial resolution number can be simultaneously recorded. Despite these innovations, there is still debate about ideal electrical transfer characteristics extracellular electrodes. This uncertainty partly due to lack systematic studies comparing electrodes different characteristics, particularly chronically implanted over extended time periods. Here a flexible, thin-film array fabricated tested, containing four distinct electrode types differing surface material topology and, thus, impedance. It found quality strongly related impedance signal amplitude unit yield negatively correlated Electrode impedances stable duration experiment (up 12 weeks) does not deteriorate. findings support expectation from theory will as decreases.

Язык: Английский

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Interfacing with the Brain: How Nanotechnology Can Contribute

ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Interfacing artificial devices with the human brain is central goal of neurotechnology. Yet, our imaginations are often limited by currently available paradigms and technologies. Suggestions for brain-machine interfaces have changed over time, along technology. Mechanical levers cable winches were used to move parts during mechanical age. Sophisticated electronic wiring remote control arisen age, ultimately leading plug-and-play computer interfaces. Nonetheless, brains so complex that these visions, until recently, largely remained unreachable dreams. The general problem, thus far, most technology mechanically and/or electrically engineered, whereas a living, dynamic entity. As result, worlds difficult interface one another. Nanotechnology, which encompasses engineered solid-state objects integrated circuits, excels at small length scales single few hundred nanometers and, thus, matches sizes biomolecules, biomolecular assemblies, cells. Consequently, we envision nanomaterials nanotools as opportunities in alternative ways. Here, review existing literature on use nanotechnology look forward discussing perspectives limitations based authors' expertise across range complementary disciplines─from neuroscience, engineering, physics, chemistry biology medicine, science mathematics, social jurisprudence. We focus but also include information from related fields when useful complementary.

Язык: Английский

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Advances in Soft and Dry Electrodes for Wearable Health Monitoring Devices

Micromachines, Год журнала: 2022, Номер 13(4), С. 629 - 629

Опубликована: Апрель 16, 2022

Electrophysiology signals are crucial health status indicators as they related to all human activities. Current demands for mobile healthcare have driven considerable interest in developing skin-mounted electrodes monitoring. Silver-Silver chloride-based (Ag-/AgCl) wet electrodes, commonly used conventional clinical practice, provide excellent signal quality, but cannot monitor long-term due gel evaporation and skin irritation. Therefore, the focus has shifted dry that can operate without gels extra adhesives. Compared ones offer various advantages terms of ease use, stability, biocompatibility. This review outlines a systematic summary latest research on high-performance soft electrodes. In addition, we summarize recent developments materials, biocompatible manufacturing methods, strategies promote physical adhesion, methods higher breathability, their applications wearable biomedical devices. Finally, discuss developmental challenges while suggesting directions future studies.

Язык: Английский

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